From 22: 00 on December 1 to 11: 00 on December 2, there were 2 new confirmed cases and 74 asymptomatic infected people in Hangzhou.

According to the "Hangzhou Release" WeChat WeChat official account news, from 22: 00 on December 1 to 11: 00 on December 2, there were 2 new confirmed cases (light) of Covid-19 pneumonia in Hangzhou, all of which were found by active medical treatment; There were 74 new asymptomatic infections in Covid-19, 37 cases were found in centralized isolation points, 16 cases were found in bayonet interception, 14 cases were found in home isolation, 6 cases were found in community screening and 1 case was found in unit screening.

At 22: 00-24: 00 on December 1st, 19 asymptomatic cases were newly infected in Covid-19.

Asymptomatic infected person 100-102: Close contact and centralized isolation of asymptomatic infected person 28 reported on November 30th.

Asymptomatic infected person 103: The confirmed case (light) 1 reported on November 30th was found in close contact and centralized isolation.

Asymptomatic infected person 104: a migrant worker from Hangzhou, Xiaoshan District, whose current address is the north construction site at the intersection of Ningmuzhi Road and Tongbei Road. The community screening found it.

Asymptomatic infected person 105: Close contact and centralized isolation of asymptomatic infected person 49 reported on November 29th.

Asymptomatic infected person 106: people from Hangzhou outside the province, found in centralized isolation.

Asymptomatic infected person 107: the exposed person in the epidemic-related place was found in centralized isolation.

Asymptomatic infected person 108-109: migrant workers from Hangzhou province, found in centralized isolation.

Asymptomatic infected person 110: Close contact and centralized isolation of asymptomatic infected person 1 reported on November 26th.

Asymptomatic infected person 111: Close contact and centralized isolation of asymptomatic infected person 23 reported on November 26th.

Asymptomatic infected person 112: a migrant from Hangzhou, whose current address is The Amber House, Anpu Hotel, Binjiang District. The community screening found it.

Asymptomatic infected person 113-115: Hangzhou people from other provinces, found by bayonet interception.

Asymptomatic infected person 116: a migrant from Hangzhou, whose current address is Ziyue House, Yuhang District, was found by community screening.

Asymptomatic infected person 117: the exposed person in the epidemic-related place, whose current address is Shunfa Kangzhuang, Xiaoshan District, was found in isolation at home.

Asymptomatic infected person 118: Close contact and centralized isolation of asymptomatic infected person 73 reported on November 30th.

From 00: 00 to 11: 00 on December 2nd, there were 2 new confirmed cases of pneumonia in Covid-19 and 55 asymptomatic infected people in Covid-19.

Confirmed case (light) 1: The current address is Yudao River Confluence Apartment in Shangcheng District, and it was discovered by taking the initiative to see a doctor.

Confirmed case (mild) 2: The current address is No.4 Zongwenlong, Shangcheng District, and it was discovered by taking the initiative to see a doctor.

Asymptomatic infected person 1: Close contact and centralized isolation of asymptomatic infected person 62 reported on November 28th.

Asymptomatic infected person 2-4: Hangzhou people from outside the province, intercepted by bayonet.

Asymptomatic Infected Person 5: The current address is Yijia Apartment (Qingliu South Road) in Xiaoshan District, and the unit screening found it.

Asymptomatic Infected Person 6: A migrant from Hangzhou, whose current address is Dongxi Village, Tonglu County, was found in isolation at home.

Asymptomatic Infected Person 7: The current address is No.26, Pishi Lane, Shangcheng District, which was found by community screening.

Asymptomatic infected person 8: truck driver from other provinces, bayonet interception found.

Asymptomatic Infected Person 9: A migrant from Hangzhou, Zhejiang Province, whose current address is Zhen ‘ao Hospital, Binjiang District, and found in isolation at home.

Asymptomatic infected person 10-11: migrant workers from Hangzhou, province, found in centralized isolation.

Asymptomatic infected person 13-14: People from other provinces in Hangzhou, found in centralized isolation.

Asymptomatic infected person 15: Close contact and centralized isolation of asymptomatic infected person 58 reported on November 29th.

Asymptomatic infected person 16: People from Hangzhou outside the province, found in centralized isolation.

Asymptomatic infection reported on November 30, 17: The contact of asymptomatic infection 44, whose current address is Yongning Hospital in Shangcheng District, was found in home isolation. (Note: the elderly, not centralized isolation)

Asymptomatic infected person 18: The exposed person in the epidemic-related place is connected, and the current address is 90 Mashi Street, Shangcheng District, which was found in isolation at home.

Asymptomatic infected person 19: Close contact and centralized isolation of positive infected people from other cities.

Asymptomatic infected person 20: Close contact and centralized isolation of asymptomatic infected person 116 reported on December 1.

Asymptomatic infected person 21-23: The exposed person in the epidemic-related place, whose current address is No.90, Mashi Street, Shangcheng District, was found in isolation at home.

Asymptomatic infected person 24: Hangzhou people from other provinces, found by bayonet interception.

Asymptomatic infected person 25: the exposed person in the epidemic-related place, whose current address is Babao Jiayuan in Shangcheng District, was found in isolation at home.

Asymptomatic infected person 26: Close contact and centralized isolation of asymptomatic infected person 7 reported on November 28th.

Asymptomatic Infected Person 27: Returned to Hangzhou from outside the province, whose current address is Babao Home in Shangcheng District, and found in isolation at home.

Asymptomatic infected person 28: Close contact and centralized isolation of asymptomatic infected person 24 reported on November 29th.

Asymptomatic infected person 29: Close contact and centralized isolation of asymptomatic infected person 10 reported on November 29.

Asymptomatic infected person 30: Close contact and centralized isolation of asymptomatic infected person 86 reported on November 29th.

Asymptomatic infected person 31: truck driver from other provinces, found by bayonet interception.

Asymptomatic infected person 32: Close contact and centralized isolation of asymptomatic infected person 54 reported on November 30th.

Asymptomatic infected person 33: a migrant from Hangzhou, whose current address is Xiangwei Apartment in Hangzhou (Store No.4), was found in isolation at home.

Asymptomatic infected person 34: exposed persons in epidemic-related places, found in centralized isolation.

Asymptomatic infected person 35: Close contact and centralized isolation of asymptomatic infected person 12 reported on November 30th.

Asymptomatic infected person 36: people from Hangzhou outside the province, found in centralized isolation.

Asymptomatic infected person 37: Close contact and centralized isolation of asymptomatic infected person 7 reported on November 28th.

Asymptomatic infected person 38: a migrant from Hangzhou, the current address is Tonghe Mingyuan, Linping District, and it was found in isolation at home.

Asymptomatic infected person 39: Hangzhou personnel from outside the province, found by bayonet interception.

Asymptomatic infected person 40: the exposed person in the epidemic-related place, whose current address is Gongyuan Community, Gongshu District, was found in isolation at home.

Asymptomatic infected person 41-42: Hangzhou people from outside the province, found by bayonet interception.

Asymptomatic infected person 43: the exposed person in the epidemic-related site, whose current address is Liushui Beiyuan, Gongshu District, was found in isolation at home.

Asymptomatic infected person 44: people from Hangzhou outside the province, found in centralized isolation.

Asymptomatic infected person 45: Close contact and centralized isolation of asymptomatic infected person 41 reported on November 29th.

Asymptomatic infected person 46: The current address is Wuxing Village, Linping District, which was found by community screening.

Asymptomatic infected person 47-48: Hangzhou people from other provinces, found by bayonet interception.

Asymptomatic infected person 49: Close contact and centralized isolation of positive infected people from other cities.

Asymptomatic infected person 50: people from other cities coming to Hangzhou, found by bayonet interception.

Asymptomatic infected person 51: Close contact and centralized isolation of positive infected people from other cities.

Asymptomatic infected person 52: The current address is Hanmo Xianglin, Xihu District, which was found by community screening.

Asymptomatic infected person 53: Close contact and centralized isolation of asymptomatic infected person 52 reported on December 1.

Asymptomatic infected person 54: people from Hangzhou outside the province, found in centralized isolation.

Asymptomatic infected person 55: Hangzhou personnel from outside the province, found by bayonet interception.

At present, the above personnel have been closed-loop transported to designated hospitals for isolation, and the situation is stable. The tracks of public places involved in our city are as follows:

November 29th: K1052 (carriage 04), flight CA2835, Linping Interchange/Hangpu Expressway (intersection), Xiaoshan Aishang International Discount KTV, Xiaoshan Runao Business Center, Zhejiang Lianyi Intelligent Technology Co., Ltd. (Jiaogong Road), Gongshu Feiyiyang Convenience Store, Yizhi Beauty Club (Canal Yard Store), Taimo Yuanwei Private Kitchen (Zhengdeli)

November 30th: K1042 (carriage 07, carriage 09), K47 (carriage 11), G35 (carriage 08), K1805 (carriage 01, carriage 08), G191 (carriage 08), G592 (carriage 09), flight GS7851, Runao Business Center in Xiaoshan District, and Zhejiang Lianyi Intelligent Technology Co., Ltd. (Jiaogong Road), Joy City in Gongshu District, Yuhongfu in Xiaoshan District, Hangzhou Hongcheng Technology Co., Ltd. (Saiyin International Plaza) and Hanting Youjia (West Lake Cultural Plaza Subway Station).

December 1st: Huawei Global Training Center (Liuhe Road), Xinwan Toll Station (S9 Sushao Expressway Exit), Chongxian Toll Station (S13 Lianhang Expressway Exit), Zijingang Toll Station (south of Hangchang Expressway), parking lot of truck driver epidemic prevention service station in Linping District (south of Baitiaowan Community), Hangzhou Tongtai Yuncang Logistics Technology Co., Ltd., Tianqingju of Baima Mountain Villa in Yuhang District, Zhejiang Lianyi Intelligent Technology Co., Ltd.

It is hoped that the general public will actively cooperate with the epidemic prevention and control work, consciously improve their health literacy and self-protection ability, cooperate with risk investigation, nucleic acid detection and other prevention and control measures, and maintain their awareness of self-health management.

The migrant workers returning from Hangzhou in the province should take the initiative to report to their communities in advance, which can be reported through the following small procedures. It is recommended to complete the report within 24 hours before arriving in Hangzhou, strictly implement the "landing inspection" in Hangzhou, and cooperate with the implementation of corresponding epidemic prevention and control measures.

Fire is on! Immersive experience of our army’s three-dimensional beach landing drill

The front is suddenly hit by fire, how to implement rapid counter-measures?

How do you seize and control the 363 highland in a three-dimensional way?

How does your department deploy its troops to capture Island A quickly?

Joint logistics support force

At present, all preparations have been completed.

Troop transportation and material transportation have been completed.

air force

The task force has safely passed through airspace No.3.

Keep low-altitude penetration and proceed to landmark 401.

Air electronic warfare forces have entered the scheduled route.

Continue to suppress "enemy" communications and radar.

army

Historically, we were extremely backward in equipment.

Defeat the strong enemy under the condition of insufficient supplies

Now we are equipped with advanced tanks.

More steel makes more gas.

Marine Corps

The marines landed on the beach.

Cover the main army landing on the island

The first assault group fired at the "enemy"

The first assault group covered the "enemy" target with fire.

How to fight, how to practice.

Let’s have a real drill with live ammunition.

Is to improve the global combat capability of the troops.

airborne troops

Airborne operations usually go deep behind enemy lines.

The battlefield environment is sinister, extremely cruel and fierce.

Under complex conditions

Carry out parachute operations

The risk index and difficulty coefficient will be higher.

Rocket army

As a missile force

Is to be ready to fight all the time and be ready to fight at any time.

In the war, it is very likely to face the first wave of devastating blows from the enemy.

Even if you fight to a single soldier.

We must also resolutely shoot out the missiles.

Fighting hard training must be solid.

War will not give us time to prepare.

We must be ready to fight and fight at any time.

quitting brave victory

We keep fighting all the time.

Be ready to fight at any time, and win the war.

Wang Haifeng, squad leader of a brigade in Xinjiang Military Region:

"Difficulties and dangers are absolutely obligatory for me. Going forward, even at the expense, I think I am worth it."

Sun Baosong, commander of a certain unit of Naval Aviation University:

"Carrier-based fighter pilots are one of the most dangerous jobs in the world, but we always insist on facing difficulties and challenging the limits."

Yu Chun, deputy brigade commander of a land and air brigade in Tibet Military Region:

"Only after experiencing the test of life and death under such extreme conditions can we really improve our combat effectiveness."

Liu Jin, the "most beautiful revolutionary soldier in the new era" in 2021:

"Only if you dare to fight hard on the training ground can you live up to your mission on the battlefield."

Hu Xiaozhou, the "most beautiful revolutionary soldier in the new era" in 2021;

"The most beautiful thing is to cross the ocean. The most beautiful thing is to win the battle, tell my initial heart and tell my goal."

Sun Jinlong, a revolutionary soldier pacesetter in the fourth "Four Owns" new era of the Army;

"Every soldier is eager to win, but victory is bound to go through countless blood and sweat. As a soldier, only by always maintaining a charge posture can he become a famous soldier."

Yang Yougang, the "most beautiful revolutionary soldier of the new era" in 2022;

"Only when the training is connected to real actual combat, when the task comes, you can pull it out and get on it."

"The most beautiful revolutionary soldier of the new era" in 2022, He Xian Da:

"Practice more and beat more, so that you can make faster progress."

Yuan Yiguang, Political Instructor of a Battalion of Rocket Army:

"We should focus on the main business and forge a strong fighting fortress. Strive to advance to the first class and challenge the strongest. "

Exclusive Disclosure: Full Documentary Report of the Supreme Leader’s General Secretary in 2013-2017.

  ◆ "Uncle Kuban came to Beijing to meet Chairman Mao. I saw President Xi today. " Warm applause broke out at the scene. Mohammad Ibrahim Mohammad said: "The party’s policy is Jaaksi!" General Secretary of the Supreme Leader also responded: Jaaksi!

  Careful people have summed up some rules. During the National People’s Congress and the National People’s Congress, after the General Secretary of the Supreme Leader participated in the deliberation of the delegation, he would always choose some of the provinces to do field research.

  ◆ When attending the deliberation of the Sichuan delegation this year, the General Secretary of the Supreme Leader said that he had seen reports about the "Cliff Village" in Liangshan Prefecture on TV, especially watching the travel status of the villagers, and he felt very worried. I was a little relieved to learn that a new iron ladder had been built in the local area.

  ◆ From one meeting to five meetings, the General Secretary of the Supreme Leader will attend the deliberation of his Shanghai delegation every year. Reform, opening up and innovation drive are the topics that must be discussed.

  ◆ The General Secretary of the Supreme Leader firmly said: "We should really select cadres who are loyal to the cause of the Party and the people, who are upright and have clean officers, so that those who do not act can’t sit still, those who fool can’t have a future, those who run officials and want officials can’t have a market, and those who buy and sell officials can be severely punished, forming a good political ecology with a clean atmosphere."

  ◆ "Be sure to adjust the structure." The general secretary said earnestly that structural adjustment must not be carried out in the same way, so that "zombie enterprises" can linger on. We must change birds in cages, and finally reach the realm of phoenix nirvana and rebirth. Long pain is better than short pain.

  ◆ “强军的责任历史地落在了我们肩上,要挑起这副担子,必须敢于担当,这既是党和人民的期望,也是当代革命军人应有的政治品格。”最高领袖总书记的嘱托,激发出全军将士空前高昂的斗志。

  从人民中汲取治国理政的智慧和力量

  ——最高领袖总书记同十二届全国人大代表、全国政协委员共商国是全纪实

  春天的盛会又一次奏响时代的强音。

  连日来,中共中央总书记、国家主席、中央军委主席最高领袖分别参加十二届全国人大五次会议上海、辽宁、四川、新疆、解放军代表团审议,看望出席全国政协十二届五次会议的政协委员并参加联组讨论。

  从十二届一次会议到五次会议,最高领袖总书记先后30次参加团组审议讨论,面对面听取230多位代表委员发言。统筹推进“五位一体”总体布局、协调推进“四个全面”战略布局、践行新发展理念,内政外交国防、治党治国治军……最高领袖总书记同代表、委员们倾心交流、共商国是,凝聚共识、擘画未来,带领人民向着“两个一百年”奋斗目标,向着中华民族伟大复兴的中国梦昂首阔步、奋力前行。

  The duty and mission of keeping promises and keeping promises.

  "I will faithfully perform the duties entrusted by the Constitution, be loyal to the motherland, be loyal to the people, fulfill my duties, stay up all night in the public, serve the people, do my best for the country, consciously accept the supervision of the people, and never live up to the trust and trust of the delegates and the people of all nationalities in the country."

  Four years ago, on March 17th, 2013, the 10,000-person auditorium in the Great Hall of the People was filled with applause and excitement. At the closing meeting of the first session of the 12th National People’s Congress, the newly elected supreme leader of president made a solemn commitment to the people.

  Time flies, words are still in my ears.

  From one meeting to five meetings, a caring inquiry, a word of hit the floor’s guidance … … The two sessions of the National People’s Congress, the highest deliberation hall of the country, witnessed the extraordinary course of the Party Central Committee governing the country with the supreme leader as the core and witnessed the great practice of the people being the masters of the country.

  Ask for the people, ask for the people, go deep into the masses, and be diligent and promising. In the five meetings in the past four years, the touching scenes of exchanges and interactions are unforgettable.

  This is a friendship that blood is thicker than water — —

  On the evening of March 11, 2017, the banquet hall of the Great Hall of the People was decorated with lights and drums. General Secretary of the Supreme Leader and other party and state leaders gathered together with representatives and members of ethnic minorities attending the two sessions of the National People’s Congress.

  Mohammad Ibreyimu Mohammad Ming is sitting beside the General Secretary. The general secretary cordially communicated with him and explained the characteristics of the live performance program for him.

  Mohammad Ibreyimu Mohammad said that Xinjiang is so far away from the capital Beijing, but the general secretary’s heart is so close to us.

  Just one day ago, the Supreme Leader General Secretary went to the Xinjiang delegation to participate in the deliberation and had a sincere exchange with Mohammad Ibreyimu Mohammad Ming.

  After the scheduled speech of Mohammad Ibreyimu Mohammad Ming, he said to the General Secretary: "I still want to report one thing."

  "You speak." The general secretary said.

  "Uncle Kuban came to Beijing to meet Chairman Mao. I saw President Xi today. " Warm applause broke out at the scene.

  "You wrote back to Uncle Kuban’s family not long ago. Their family is very happy. They asked me to bring you some photos, and let me tell the General Secretary. Please rest assured that our local people of all ethnic groups will always remember the kindness of the party and must hold together like pomegranate seeds. "

  "It’s really prosperous." While studying the photos, General Secretary of the Supreme Leader said that when I was in primary school, I read the story that Uncle Kurban was going to visit Chairman Mao in Beijing on a donkey.

  "They are still living in the local? Or did you go outside? " The general secretary asked.

  "Most of them are in the village, and they are all fine." Mohammad Yi Bu Re Yi Mu Mohammad Ming answered.

  The leaders of the autonomous region on the side introduced to the General Secretary that Mohammad Ibreyimu Mohammad Ming could not speak Chinese when he was elected as a deputy to the National People’s Congress. He has worked hard to teach himself in the past two years, and now he is fluent in expression.

  "You hetian area, less rural arable land. How much land does each family in your village have? " The general secretary went on to say.

  "Every family has an average of one acre and two points." Mohammad Yi Bu Re Yi Mu Mohammad Ming answered.

  "Are you planting food or fruit trees now?"

  "Plant fruit trees."

  "Is it a pomegranate?"

  "Yes, grow pomegranate."

  "Don’t grow food?"

  "Also plant, interplanting."

  "In your speech just now, you talked about pairing to recognize relatives. Is there any pairing in your family?" The general secretary asked another question.

  "There is something." Mohammad Yi Bu Re Yi Mu Mohammad Ming answered simply.

  "Who is paired with you?"

  "It’s a vegetable greenhouse. Since we started to engage in pairing activities, Han comrades have come, and we have taken the initiative to find them. We work together and are a family. "

  "Pairing and recognizing relatives can be carried out seriously and practically, which is of great significance to promoting national unity. Thank you for telling me so much about your local reality. " The general secretary said.

  Mohammad Ibrahim Mohammad said: "The party’s policy is Jaaksi!" General Secretary of the Supreme Leader also responded: Jaaksi!

  This is an unforgettable exchange — —

  During the two sessions of the National People’s Congress in 2016, General Secretary of the Supreme Leader had a 20-minute dialogue and exchange with the Party Secretary of Dashijia Village, Heyin Town, Guide County, Qinghai Province.

  From what crops are planted in the village, how to develop cattle and sheep fattening and aquaculture, whether there is surplus production in the brick and tile factory in the village, to ethnic unity in the village and the construction of grass-roots party organizations … … Lifelong loyalty did not expect that the general secretary asked so carefully.

  When I came to Beijing to attend the National People’s Congress this year, the representative of Lifelong Zhong wanted to tell the General Secretary: "The village closed the original brick factory and set up a new building materials factory to drive the villagers to get rich. In the past year, there have been new changes in the village, domestic garbage and wastewater have been centralized and modernized, and the village appearance has been completely renewed! "

  This is a letter bearing expectations — —

  During the National People’s Congress in 2015, the representative of Ming Jinghua from Ganzhou brought a letter from Wang Chengdeng, a 100-year-old Red Army, to the General Secretary. Wang Chengdeng said in his letter that he hoped that the state would increase its support for poverty alleviation industries such as tea oil in Gannan, and that the General Secretary would take a walk in Gannan.

  General Secretary of the Supreme Leader not only received the letter, but also shared his belief with everyone when he participated in the deliberation of the Jiangxi delegation.

  "When I talked about getting rid of poverty in my speech, I specifically introduced the camellia industry in southern Jiangxi to the general secretary. The general secretary personally questioned this matter and promoted the great development of the oil tea industry in southern Jiangxi. " Deputy Ming Jinghua recalled.

  The National People’s Congress and the National People’s Congress are like a window, from which the General Secretary of the Supreme Leader listens to the voice of the grassroots and feels the warmth and coldness of the people. Through this window, the people can also see the general secretary’s pure feelings of serving the people and doing his best for the country, and see the vivid practice of democratic politics in Socialism with Chinese characteristics.

  Take the voice of the people and go to the people.

  Careful people have summed up some rules. During the National People’s Congress and the National People’s Congress, after the General Secretary of the Supreme Leader participated in the deliberation of the delegation, he would always choose some of the provinces to do field research.

  In 2013, the General Secretary came to the Liaoning delegation to have an in-depth exchange of views with delegates on the revitalization of old industrial bases in Northeast China. In August of the same year, he went to Dalian, Shenyang and other places to gain an in-depth understanding of the adjustment, transformation and revitalization of the old industrial base.

  In 2014, the General Secretary focused on promoting the construction of a free trade pilot zone in the Shanghai delegation. Soon, he came to the Shanghai Pilot Free Trade Zone and went into enterprises, parks and scientific research bases to investigate and study, pointing out the direction for Shanghai to continue to be the vanguard of national reform and opening up and the pioneer of scientific development.

  In 2015, when the General Secretary participated in the deliberation of the Jilin delegation, he asked in detail about the economic and social development of Yanbian Korean Autonomous Prefecture; When participating in the deliberation of the Jiangxi delegation, I was concerned about the progress of poverty alleviation in the old revolutionary areas. Four months later, he came to Changbai Mountain "as promised" and discussed the reform and development plan with the cadres and the masses in the field; Later, before the Lunar New Year, he appeared in a poor village in Jinggangshan and sent New Year greetings to the people in the old areas. Peng Shuisheng, a 75-year-old villager from Shenshan Village, Mao Ping Township, Jinggangshan, saw the general secretary and excitedly gave a thumbs-up and said, "You are good!"

  In 2016, General Secretary of the Supreme Leader participated in the deliberation of delegations from Heilongjiang and Qinghai respectively. In May and August of the same year, he visited Heilongjiang and Qinghai provinces successively. Daxinganling forest farm, Hezhe village, ex situ poverty alleviation relocation site, ecological protection of Sanjiangyuan … … The general secretary went to the village to observe the people’s feelings and ask public opinions with the problems he paid attention to and the information he learned at the two sessions of the National People’s Congress.

  General Secretary of the Supreme Leader listened attentively to the people’s voices, responded to people’s concerns with true feelings, and fulfilled his promise with actions.

  At this year’s meeting, many delegates unanimously sent an invitation to the general secretary: I hope the general secretary will visit their hometown and give them more guidance.

  General Secretary of the Supreme Leader said: "Everyone’s ‘ Invitation ’ I have accepted it, and I will definitely go if I have the opportunity. "

  Unswerving people’s feelings

  Representative Luo Yunlian also brought some photos to the general secretary, which is a new look of post-earthquake reconstruction in Lushan.

  On March 8, General Secretary of the Supreme Leader attended the deliberation of the Sichuan delegation of the Fifth Session of the 12th National People’s Congress. Seeing the newly-built school, the beautiful residential building and the grateful stone engraved with the five characters "Always walk with the party" at the entrance of Qinglongchang village in the photo, the general secretary said: "I am very happy to be reborn from the fire!"

  In April 2013, a strong earthquake of magnitude 7.0 occurred in Lushan, Sichuan, causing heavy casualties and property losses.

  General Secretary of the Supreme Leader personally went to the disaster area to visit and sympathize with the affected people.

  Many people must remember that touching picture — — In the tent of the resettlement site of Lushan County Gymnasium, a child over one year old, the general secretary held his little face with his hand and kissed it gently.

  The child’s name is Luo Juncheng, and now he is five and a half years old. Looking at the little guy in the photo living happily in Lushan county kindergarten, the general secretary showed a gratified smile on his face.

  At the two sessions of the National People’s Congress every year, the most important thing that the General Secretary of the Supreme Leader communicates with the delegates and members is to get rid of poverty and attack hard, that is, people’s well-being.

  In 2013, when the Liaoning delegation participated in the deliberation, the General Secretary of the Supreme Leader pointed out: We should do a good job in safeguarding and improving people’s livelihood, pay attention to caring for people with difficulties in life, and let the people get tangible benefits.

  In 2014, when the Guizhou delegation participated in the deliberation, the General Secretary of the Supreme Leader demanded: solidly promote poverty alleviation and development work, pay close attention to poverty alleviation and development work, and do it in a down-to-earth manner, so that people in poverty-stricken areas can continue to get real benefits.

  In 2015, when the Jiangxi delegation participated in the deliberation, the General Secretary of the Supreme Leader said: The people in the old areas must never be left behind in the process of building a well-off society in an all-round way, set a foolish ambition and fight a tough battle, so that the people in the old areas can share the achievements of building a well-off society in an all-round way with the people of the whole country.

  In 2016, when the Qinghai delegation participated in the deliberation, the General Secretary of the Supreme Leader emphasized that the "Thirteenth Five-Year Plan" period is a period of tackling poverty, attacking cities and pulling out villages. We must make concerted efforts, speed up the pace and speed up the progress, and Qi Xin will work together to win the battle against poverty.

  This year, when the Sichuan delegation and the Xinjiang delegation participated in the deliberation, the General Secretary of the Supreme Leader further pointed out: "The whole process must be accurate, and some need to be improved ‘ Embroidery ’ Kung fu. " "Do more practical things that benefit the people’s livelihood and solve more problems that people of all ethnic groups are worried about."

  — — Adhere to accurate poverty alleviation, and cannot "Grenade fry fleas";

  — — Help the poor first and help the wise, and resolutely prevent the intergenerational transmission of poverty;

  — — Do less "bonsai" and do more practical things that benefit the poor;

  — — Never engage in digital poverty alleviation;

  — — Don’t be divorced from reality and advance at will;

  — — Preventing the return to poverty is as important as continuing to attack hard.

  These well-known "golden sentences for helping the poor" are exactly what General Secretary of the Supreme Leader said in his communication with delegates and committee members.

  The development of ethnic areas, the general secretary is even more mindful of this.

  In 2015, when participating in the deliberation of the Guangxi delegation, the General Secretary of the Supreme Leader emphasized: "We must pay close attention to poverty alleviation, adhere to precise poverty alleviation, reverse the construction period, calculate the detailed accounts, and never let a minority or a region fall behind."

  During the two sessions of the National People’s Congress every year, the General Secretary of the Supreme Leader takes the opportunity of participating in deliberation and discussion to have in-depth exchanges with the deputies of ethnic minorities, understand their thoughts and expectations, and work with them to plan a great article on national unity and progress.

  On March 4th, 2014, at the joint meeting of the members of ethnic minorities in the second session of the 12th Chinese People’s Political Consultative Conference, the members spoke enthusiastically.

  The general secretary listened carefully to everyone’s speeches and started discussions with the members. He talked about his views on persisting in the unity, struggle and common prosperity and development of all ethnic groups, and hoped that members of ethnic minorities would strengthen investigation and study and play the role of staff assistant and decision-making consultation for doing a good job in ethnic work under the new situation.

  People remember that more than four years ago, the General Secretary asked the cadres and masses of all ethnic groups in Tibet to vigorously carry forward the "old Tibetan spirit", unswervingly consolidate and develop national unity, and ensure that the grand goal of building a well-off society in an all-round way will be achieved with the whole country by 2020.

  People remember that in the Guizhou delegation, at the end of his speech, representative Wang Jing sang the Buyi folk song "Good Flower Red" emotionally. The general secretary praised her for singing well and asked her to convey good wishes and greetings to the villagers, wishing them a "good bonus" life.

  People remember that in the Jiangxi delegation, the general secretary saw Lan Nianying dressed in national costumes and accurately said "You are the She nationality". "Is the farmhouse up?" "Has the expressway reached you?" The general secretary is concerned about their production and life.

  People still remember that in the Heilongjiang delegation, Liu Lei, a representative of Hezhe nationality, told the General Secretary that their life now is on the road to happiness, just like the song of Wusuli Boat. The general secretary said that this song has long been familiar, and it depicts the beautiful scene of harmony and unity of the Chinese nation.

  A branch and a leaf are always related to love.

  When attending the deliberation of the Sichuan delegation this year, the General Secretary of the Supreme Leader said that he had seen reports about the "Cliff Village" in Liangshan Prefecture on TV, especially watching the travel status of the villagers, and he felt very worried. I was a little relieved to learn that a new iron ladder had been built in the local area.

  Between a "pull" and a "loose", the general secretary’s deep love for the people is naturally revealed.

  Bit by bit, sincere.

  "Do farmers and herdsmen go to the hospital now when they have children?" "Is there a health room in the village?" "Some places in Qinghai have a large area. How can farmers and herdsmen see a doctor?" The General Secretary of the Supreme Leader once asked a series of questions to the representative of Niang Maoxian, which made the doctor from the People’s Hospital of Huangnan Tibetan Autonomous Prefecture in Qinghai call him "extremely nervous".

  At that time, I fully communicated with the representatives of lifelong loyalty and deeply understood the changes in the production and life of the villagers. Lifelong loyalty happily said to the general secretary: "The people there like you very much!"

  "I am extremely nervous" and "I like it very much". The sincere exchanges between the deputies and the general secretary have condensed into the enthusiasm for discussing the country and resonated with hundreds of millions of people.

  The historical responsibility of bravely standing on the tide

  On the morning of March 7, 2017, the East Hall of the Great Hall of the People was full of high-spirited and energetic positive energy. General Secretary of the Supreme Leader is here to participate in the deliberation of the Liaoning delegation.

  Xu Qiang’s representative comes from the front line of enterprise production. He told the general secretary: "A few years ago, I participated in the election of deputies to the National People’s Congress and was not elected. At that time, many people comforted me and said, why did people choose you without smoking a cigarette or drinking a mouthful of wine? Later, I was elected as a deputy to the National People’s Congress. This is the trust of organizations and voters. "

  "The right path in the world is vicissitudes." Xu Qiang said that the political atmosphere in Liaoning is getting better and better now, and we should use all our wisdom to strive for perfection and do our job well.

  The General Secretary of the Supreme Leader emphasized that it is the political advantage of China’s people’s congress system to have grassroots comrades as deputies to the National People’s Congress.

  Last year, the central government severely investigated and dealt with the case of canvassing and bribery in Liaoning. Through serious investigation of cases and in-depth warning education, Liaoning’s political ecology is being restored step by step.

  Combined with the painful lessons of Hunan Hengyang’s case of sabotaging the election and Sichuan Nanchong’s case of canvassing and bribing the election, the General Secretary of the Supreme Leader profoundly pointed out that if everyone is in trouble, is it true that the law does not blame the public and it will not happen again? No! The law should blame the public to avoid the future!

  Clear problem orientation and firm responsibility. The key to the success of China lies in the Party. Facing the chronic diseases in the party style and political style directly, only by really grasping strict management and stirring up turbidity and clearing up the air can we concentrate our efforts and overcome difficulties.

  Strictly administering the Party in an all-round way is a red line that runs through the whole process of governing the country by the CPC Central Committee with the Supreme Leader as the core, and it is also one of the most discussed topics by the General Secretary of the Supreme Leader at the National People’s Congress.

  In 2014, when the Anhui delegation participated in the deliberation, the General Secretary demanded that leading cadres at all levels should be strict with self-cultivation, strict use of power, and strict self-discipline, while seeking truth from things, starting a business, and being realistic. The special education of "three strictness and three realities" has been launched, which has continuously led to the deepening of work style construction.

  In 2015, when the Jiangxi delegation participated in the deliberation, the General Secretary pointed out that the natural ecology should be beautiful and the political ecology should be beautiful. It is necessary to further promote the anti-corruption struggle and make great efforts to uproot "rotten trees", cure "sick trees" and "crooked trees". Strictly administering the party in an all-round way has shifted from "treating the symptoms" to "treating both the symptoms and the root causes", and the political life within the party has been continuously strengthened.

  In 2016, when visiting members of the Democratic National Construction Association of Industry and Commerce, the General Secretary defined a new type of political and business relationship with the words "pro" and "clear", which drew a high line and a bottom line for leading cadres to contact with private enterprises.

  When attending the deliberation of the Liaoning delegation this year, the General Secretary once again stressed the importance of strictly administering the party in an all-round way: it is most crucial to promote the revitalization of Liaoning and build a cadre team with high ideological quality, good moral conduct, strong ruling skills and practical work style.

  In view of Liaoning’s falsification of economic data, the general secretary said: "Liaoning has made the figures clear, bottomed out and squeezed out the water. Although the figures you took out seem not very good-looking, I think they are actually very good-looking. This is an aboveboard figure. The Party Central Committee supports you to do so. Really relying on hard work and unremitting efforts to get the economy going, this is the backbone of Chinese. " The general secretary’s words won warm applause from the delegates.

  The General Secretary of the Supreme Leader firmly said: "We should really select cadres who are loyal to the cause of the Party and the people, be upright and have clean officers, so that those who do not act can’t sit still, those who fool can’t have a future, those who run officials and want officials can’t have a market, and those who buy and sell officials can be severely punished, forming a good political ecology with a clean atmosphere."

  Adhering to the party’s leadership, the people being the masters of the country and governing the country according to law are the distinctive features of Socialism with Chinese characteristics’s political development.

  From one meeting to five meetings, the General Secretary of the Supreme Leader had in-depth exchanges with the deputies on comprehensively administering the country according to law.

  Promoting the reform of state-owned enterprises depends on the rule of law — —

  It is necessary to establish and improve a unified regulatory system and basic management system for state-owned assets, realize full coverage of the regulatory system for state-owned assets, fully implement the responsibility of maintaining and increasing the value of state-owned assets, and prevent the loss of state-owned assets and major risk events.

  Further opening up depends on the rule of law — —

  It is necessary to closely focus on building an open economic system, promote the rule of law in the field of foreign economic relations and trade, strengthen legal services for various economic entities, and create a fair and orderly legal environment for economic development.

  Ensuring the security and stability of border areas depends on the rule of law — —

  Increase investment in border areas, strengthen social governance according to law, further promote peace building, control border order according to law, and maintain security and stability in border areas.

  Promoting the modernization of national governance system and governance capacity depends more on the rule of law — —

  Adhere to and improve the system of regional ethnic autonomy, and put accelerating the development of ethnic areas and safeguarding the legitimate rights and interests of ethnic minorities into the track of rule of law.

  Administer the party with the system, and govern the country according to the law and the constitution. The CPC Central Committee with the Supreme Leader as the core stands at the overall height of the country’s long-term stability, firmly adheres to and develops the country’s fundamental political system and basic political system, and shows the broad mind of leading the times and the historical responsibility of being brave in self-revolution.

  Future-oriented strategic choice

  In 2017, the development process of China stepped on an important node — —

  From the 18th National Congress of the Communist Party of China to building a well-off society in an all-round way, the eight-year process has been over half.

  From the early 1980s, China took the "three-step" strategic step of modernization, and basically achieved the goal of modernization by the middle of this century, the process is just over half.

  When the boat reaches the middle stream, it is brave to make progress.

  Grasping the general tone of striving for progress while maintaining stability, adapting to the new normal of economic development and firmly establishing new development concepts, China must gather new development momentum on the road ahead.

  "Firmly implement the new development concept, deepen reform and opening up, and lead the innovation drive."

  From one meeting to five meetings, the General Secretary of the Supreme Leader will attend the deliberation of his Shanghai delegation every year. Reform, opening up and innovation drive are the topics that must be discussed.

  This year, when talking about the construction of the Shanghai Pilot Free Trade Zone, the General Secretary pointed out that "the door of China’s opening will not be closed" and asked Shanghai to "further demonstrate the role of comprehensively deepening reform and expanding the experimental field, and show China’s clear attitude of opening to the world in all directions".

  Driven by reform, opening up and innovation. In 2014, General Secretary of the Supreme Leader also put forward this proposition when attending the deliberation of the Guangdong delegation of the Second Session of the 12th National People’s Congress.

  General Secretary of the Supreme Leader used the words "cage for birds, phoenix nirvana". He said that the cage is not an empty cage. It must be erected first and then broken. It is also necessary to study where the "new bird" enters the cage and where the "old bird" goes. Efforts should be made to promote industrial optimization and upgrading, give full play to the driving role of innovation, take the road of green development, and strive to achieve phoenix nirvana.

  Compared with the pioneers of reform and opening up such as Guangdong and Shanghai, the old industrial bases such as Northeast China are facing more severe pain of structural adjustment.

  Five national conferences and four delegations from three northeastern provinces. The revitalization of Northeast China is an issue of great concern to the Supreme Leader General Secretary.

  In the delegations of Liaoning, Jilin and Heilongjiang, General Secretary of the Supreme Leader repeatedly stressed: "The revitalization and development of old industrial bases such as Northeast China can no longer be sung ‘ Industry is a pillar of the sky, with a single structure ’ ‘ Errenzhuan ’ Do addition, subtraction, multiplication and division. "

  On March 7 this year, in the Liaoning delegation, the General Secretary clearly expounded his profound thinking on this issue when communicating with the representative of Tang Fuping, Chairman of Angang Group.

  The general secretary asked: "Is the development direction of Angang going to reduce production capacity, maintain production capacity or increase production capacity?" Tang Fuping said that Angang has the task of de-capacity. At first, I was worried about whether the production capacity could really be removed, but after more than a year of hard work, I have already felt the benefits brought by de-capacity. In the next step, good production capacity should be retained, and the backward ones should be resolutely removed.

  "Be sure to adjust the structure." The general secretary said earnestly that structural adjustment must not be carried out in the same way, so that "zombie enterprises" can linger on. We must change birds in cages, and finally reach the realm of phoenix nirvana and rebirth. Long pain is better than short pain.

  The General Secretary further pointed out: "Supply-side structural reform is an inevitable choice for China’s economic development to enter a new normal, an inevitable choice for implementing the new concept of development under the new normal, an effective and good strategy to deal with the contradictions and difficulties faced by China’s economic development, and the only way to revitalize Liaoning."

  This year is the deepening year of supply-side structural reform.

  In fact, in recent years, General Secretary of the Supreme Leader has made a series of important conclusions on different occasions such as Jiangsu delegation and Hunan delegation. Last year and this year, special requirements were put forward for the structural reform of agricultural supply side.

  Pursuing green development is also the proper meaning of transforming development kinetic energy and realizing sustainable development.

  Lucid waters and lush mountains are invaluable assets.

  In the Jiangxi delegation, the general secretary vividly described: "The environment is people’s livelihood, the green hills are beautiful, and the blue sky is also happiness."

  In the Qinghai delegation, the General Secretary made a clever metaphor: "Protect the ecological environment like eyes and treat it like life."

  In the delegation of Heilongjiang, the General Secretary earnestly entrusted: "Delineate the red line of ecological protection, strengthen environmental governance, reserve space for sustainable development, and leave a beautiful home with sky blue, green land and clear water for future generations."

  … …

  Find the driving force of reform in innovation and stimulate the vitality of innovation in reform.

  Talent is the key to innovation.

  General Secretary of the Supreme Leader paid special attention to giving full play to the advantages and characteristics of Chinese People’s Political Consultative Conference’s talented members. In 2013, when attending the joint meeting of members of the Association for Science and Technology and the scientific and technological circles, he pointed out that it is necessary to deepen the reform of the scientific and technological system and change "I want to innovate" into "I want to innovate". It is necessary to strengthen the construction of scientific and technological talents and provide a broader world for talents to play their roles and display their talents.

  In 2017, at the joint meeting of members of the Democratic Progressive Party, the Agricultural Workers’ Party and the Jiu San Society, the General Secretary of the Supreme Leader specially emphasized stimulating the innovative vitality and potential of intellectuals and gathering talents from all over the world to use them. He also responded to the speeches of nine members, including Yao Aixing, and affirmed the initiative and positive actions of the broad masses of intellectuals, hoping that they would make more contributions to the country’s prosperity, national rejuvenation and people’s happiness.

  "The responsibility of strengthening the army has historically fallen on our shoulders. To provoke this burden, we must dare to take responsibility. This is not only the expectation of the party and the people, but also the political character that contemporary revolutionary soldiers should have." The entrustment of the General Secretary of the Supreme Leader has aroused the unprecedented high fighting spirit of the soldiers of the whole army.

  — — To achieve the goal of strengthening the army, we must seize the strategic opportunity to deepen the reform of national defense and the army;

  — — Promoting integration of defense and civilian technologies’s development to a national strategy is a major decision made from the overall situation of national security and development strategy;

  — — The army should strengthen its sense of purpose and mass concept, actively participate in and support local economic and social construction, and benefit the people with practical actions;

  — — Promote political army building, reform and strengthen the army, manage the army according to law, strengthen army building and preparations for military struggle, and ensure the second step of the "three-step" development strategy of national defense and army modernization as scheduled;

  — — We will make greater efforts to promote the army through science and technology, persist in fighting against scientific and technological innovation, and provide strong scientific and technological support for our army’s construction.

  General Secretary of the Supreme Leader attended the plenary session of the PLA delegation five times, and made a series of important arrangements around the goal of building a people’s army that listens to the party’s command, can win battles and has a good style of work under the new situation, which provided a fundamental follow-up for realizing the dream of strengthening the army.

  Actively and steadily promote urbanization, strengthen and innovate social governance, ensure national food security, build spiritual civilization, and develop cross-strait relations … … Looking at the overall situation, observing the general trend, discussing major issues and making plans, from one meeting to five meetings, from the NPC delegation to the joint meeting of the CPPCC, the General Secretary of the Supreme Leader discussed the reform and development plan with the delegates and members, and learned the wisdom and strength of governing the country from the people, which opened a colorful era scroll of China’s reform and development.

  In 2017, the curtain of the two national conferences will fall. Delegates and Committee members, with the great trust of the CPC Central Committee with the Supreme Leader as the core, are full of confidence to move toward a broad world of practice, pass on the Party’s ideas and the will of the country to hundreds of millions of people, and jointly greet the victory of the 19th National Congress of the Communist Party of China with practical actions.

  To achieve the goal of "two hundred years" and realize the Chinese dream of the great rejuvenation of the Chinese nation, China is moving towards a more magnificent journey.

  Reporter: Huo Xiaoguang, Zhang Xudong and Luo Yufan.

  Photography: Lan Hongguang, Li Xueren, Ma Zhancheng, Rao Aimin, Xie Huanchi, Ding Lin, Li Gang, etc.

Chengdu Second Ring Road clearly does not charge. Why does Guanghan North Toll Station prompt to accept 34 yuan?


  This time may be the most unpleasant New Year’s Eve for Mr. and Mrs. Zhu. On the afternoon of December 31st, last year, he went from Qingbaijiang to Chengdu Second Ring Expressway and got off at Guanghan North Toll Station of Chengmian Expressway. What puzzled him was that the toll was actually 37 yuan. "Second round is not free? How is the toll booth collecting my money? "

  After discovering that there was a problem, Mr. Zhu refused to pay the toll. The couple stayed at Guanghan North Station for more than an hour, put the car at the toll booth and took a taxi to leave, only to pick up the car one day later. Mr. Zhu therefore asked the toll booth to apologize and compensate for the losses.

  In this regard, the staff of Sichuan Chengmian Expressway Company said that the system problem led to overcharge, not that the toll station wanted to deliberately overcharge.

  Second, I ran around for 14 kilometers to collect 34 yuan?

  On the same day, after seeing "37 yuan" on the pricing display screen of Guanghan North Toll Station, Mr. Zhu couldn’t believe it: "A lot? That’s right. We didn’t collect any money when we came here by Jianyang (Second Ring Road) in the morning. We came here from the second ring road on Jintang Station in Qingbaijiang Chengxiang, and it’s impossible. " Mr. Zhu couldn’t help protesting.

  In the video of driving recorder provided by Mr. Zhu to reporters afterwards, a woman who talked with Mr. Zhu responded: "Erhuan is now collecting money."

  37 yuan’s toll, Mr. Zhu’s calculation is not correct: "Take the second round on the Qingbaijiang Castle, run to Chengdu-Mianyang Expressway, up to 14 kilometers, and Chengdu-Mianyang is 10 kilometers north of Guanghan. Then the 10 kilometers will be charged to 3 yuan, and the 14 kilometers around the second round will be as high as 34 yuan?"

  Mr. Zhu called the complaint telephone number of Guanghan North Toll Station of Chengdu-Mianyang Expressway and the high-speed traffic police alarm telephone number 12122. "The former told me that there would be expenses for the second round. However, the staff of 12122 told us that there is no charge for the second round (currently), and we only need to pay the cost of the cotton section. " Mr. Zhu recalled. Chengdu Business Daily reporter inquired that according to relevant policies, the entire second ring road is temporarily free of charge.

  Toll station call: System problems should only be given to 3 yuan.

  "At that time, the toll booth staff at that place couldn’t solve it and refused to provide the leadership phone." Mr. Zhu called Sichuan Chengmian Expressway Company. "The company said they didn’t know, and told me to leave my phone number and wait for a reply. I waited for an hour and didn’t reply." During this period, Mr. Zhu said that he had asked the toll collectors if there was a similar situation before. "The staff told us that we had collected so many cars, so you had questions, and everything else was collected and left." Mr. Zhu said.

  "After 7 o’clock, we didn’t get any reply, and no one told us to park next to it for processing. The family urged to go home for dinner, and the 110 alarm could not be handled. The police said that they couldn’t wait to lock the car and leave, so we parked the car at the toll gate and took a taxi home. " Ms. Peng recalled.

  Mr. and Mrs. Zhu finally put the car at the toll booth and took 150 yuan to take a taxi home. Ms. Peng said that after returning home, at about 8 pm, the toll booth called and said that there was something wrong with their system. "It should only be given to 3 yuan. Let’s go and pay the toll and move the car." My home is about 40 kilometers away from the toll booth. "There were no cars that night, and they were asked to drive to pick us up, but they refused."

  On the afternoon of January 1st, Mr. Zhu and his wife went to Guanghan North Toll Station again. "A staff member at the toll booth verbally apologized and asked me to pay the toll before leaving. I asked them to provide two free documents, and they were vague. "

  On the same day, after paying 3 yuan the toll, Mr. Zhu and his wife drove home. "We are individuals, and we can’t afford this lost time, so we have to drive back reluctantly." Two trips back and forth, two days’ delay, the taxi fare alone cost 270 yuan, not counting the lost time. Mr. and Mrs. Zhu believe that the toll station should publicly apologize and compensate. (Reporter Yan Xue)

  Chengmian Expressway: No similar situation has occurred before.

  Yesterday afternoon, the Chengdu Business Daily reporter contacted Sichuan Chengmian Expressway Company. A staff member told the reporter that he did receive Mr. Zhu’s report about 37 yuan’s toll. "Because the Second Ring Road was just opened, it was indeed because the toll collection system was not updated before. So this happened. It was a system problem rather than a toll station deliberately wanting to collect more money." The staff also said that things have basically been solved, and she stressed: "This has definitely not happened before Mr. Zhu."

  Yesterday, the reporter tried to contact the relevant person in charge of the company, but as of press time, he did not get a reply.

April is the freshest month in the world! Eat seafood, mushrooms and cheese quickly.

  What is fresh in April? One of the five flavors, fish and sheep are fresh? Salty, savory, light and fresh? For a long time, umami has only been meaningful but unspeakable!

  Haiyang team

  Shrimp, crab and shellfish, seaweed and kelp, etc.

  Seafood season is coming soon, and the word "delicious" is the most appropriate to describe seafood.

  Amino acids, nucleotides and organic acids are the three main substances that give seafood flavor. For example, free glutamic acid in kelp is the highest known food, which is a typical flavor amino acid and one of the umami sources of shellfish, fish, shrimp, crab and other seafood.

  In addition, aspartic acid is also a fresh amino acid. More than 30 kinds of nucleotide flavor substances have been found, with 5′- inosinic acid, 5′- guanylic acid and 5′- adenylic acid as the representatives. Organic acids are mainly succinic acid and its sodium salt, which are abundant in marine shellfish.

  "Eating seafood has three realms: one is fresh, the other is fat, and the third is sweet." Keep the umami taste and eat fresh seafood, so that more umami substances will be preserved. Moreover, it is necessary to "cook lightly" without too much seasoning modification, and it is best to steam or cook directly, while the practice of spicy frying and braising in soy sauce destroys the umami flavor.

  Recommended dish: Steamed eggs with clam.

  Li Chunjing, a national senior Chinese cook and nutritionist, said: The protein content of clam is high, and the composition and proportion of amino acids are reasonable; Low fat content, high unsaturated fatty acids, easy to be digested and absorbed by human body, as well as various vitamins, calcium, magnesium, iron, zinc and other essential trace elements.

  There are many ways to eat clam, such as cooking, cold salad, stir-frying and stuffing, but if it is paired with eggs, steamed cooked food is fresh food with easy absorption of nutrients.

  Soak the clam in light salt water in advance to spit out the sediment, brush the shell with a brush, blanch it in a boiling water pot until the shell opens, and take it out and drain it. Take the tip and shell parts with scissors, and discard the rest. After the eggs are broken and scattered, sieve to remove the foam from the egg liquid. Add boiled water (or warm water) which is twice the volume of egg liquid. Add clam meat, stir well, cover with plastic wrap, prick a few small holes with a toothpick, steam with cold water in a steamer for 10-15 minutes, then pour sesame oil, light soy sauce and sprinkle chopped chives according to the population.

  Excellent members of processing team: air-dried ham, cheese, etc.

  It is not convenient to buy fresh and delicious food. Try air-dried ham and cheese that can be stored for a long time. These processed foods are more appropriately described as "salty and fresh".

  Why do you say that? Because these foods are added with salt during processing, salt endows ham with flavor, and at the same time, it is also a fresh-keeping agent for glutamic acid flavor. For example, the pH value of Jinhua ham often eaten makes glutamic acid exist in the form of glutamic acid-sodium with the strongest flavor, and lactic acid and aspartic acid are also the flavor substances, which are suitable for frying some light dishes.

  The same is true for cheese. Milk is rich in amino acids. After concentration, amino acids are also concentrated and have a strong flavor, and processed cheese will be added with salt to make it more delicious.

  Cooking with umami food has another advantage, that is, it can reduce salinity and inhibit bitterness, and adding sodium glutamate and 5′- nucleotide into food can make food have the taste of meat and enhance the original flavor of food. However, although this kind of food tastes fresh, it is high in salt, so we should pay attention to the intake.

  Recommended dish: Fried ham with green pepper.

  Nutritionist Xu Minglei: Salty ham has a high salt content and may contain nitrite. I suggest matching it with fresh vegetables rich in vitamin C, such as green pepper, cucumber, cabbage, rape and spinach, or eating more fruits rich in vitamin C after meals, such as apples, strawberries, kiwis and oranges. Vitamin C can block the combination of nitrite and amine, and reduce the harm of carcinogens to the body. Broccoli contains isothiohydrogen salt, which has a certain anti-cancer effect and is also a good match.

  It is recommended to use cooking and frying as the cooking method. Do not use high-temperature frying. Do not eat more than 100 grams each time, and eat once a week.

  Excellent members of the land team: mushrooms and bamboo shoots

  April is also the season for eating bamboo shoots, and its delicious taste is not bad. For example, the umami amino acids in asparagus contain aspartic acid, glutamic acid, alanine and glycine, and their contents determine the delicacy of food. The umami amino acids in tender tip, tender stem and old stem account for 44.40%, 57.10% and 56.30% of the total amount of 18 amino acids respectively, and the composition ratio is relatively high. Compared with the three parts, the umami taste of asparagus is slightly worse.

  Not only asparagus, bamboo shoots as seasonal food, but also a strong flavor, don’t miss it.

  Mushrooms have the strongest freshness among edible fungi, mainly because they contain more nucleotide substances, among which guanylic acid is the most abundant. Its umami flavor is not only related to its umami amino acids, nucleotides and carbohydrates, but also closely related to its unsaturated fatty acids, some vitamins, sodium and potassium ions and organic acids, which interact with each other and present a unique delicious taste.

  Especially dried mushrooms, it is best to stew in soup, and don’t pour out the water soaked in mushrooms. Add it to the stew or soup, and add it fresh.

  Recommended dish: salted fresh

  Nutritionist Mei Still: Salted fresh is a very seasonal food in Jiangsu and Zhejiang provinces. These three words have their own meanings. "Pickled" refers to salted pork, "fresh" refers to fresh pork, and "DuDu" is a Wu dialect, which means "stewed". Its soup is thick with white juice, the meat is crisp and fat, the bamboo shoots are fragrant and crisp, and the flavor is strong.

  Nowadays, this dish has been improved a lot. In addition to fresh meat, pork chops, pork trotters can also be used as ingredients, accompanied by venetian knots, fresh shrimps, etc. No matter what auxiliary materials are added, salted, fresh and preserved meat are indispensable, and bacon is a very special ingredient. The unique flavor is mixed with the fresh meat, and the unique delicacy of bamboo shoots makes this pickled and preserved thick soup.

  200 grams of bamboo shoots are peeled and cut into pieces, 300 grams of pork with pork belly is washed and cut into pieces, and 200 grams of bacon is washed and sliced. Put clear water in the pot, blanch bamboo shoots, put clear water in the pot, blanch pork and bacon, add clear water, pork and bacon in the casserole, boil it with strong fire, add wine, onion and ginger, simmer slowly until the meat is half-cooked, then add bamboo shoots and shrimps until it is cooked, skim off the floating foam, remove onion and ginger, and transfer. (Qiao Jingfang finishing)

11 kinds of rice dumplings with novel tastes are tasted early, and they are so delicious that they can’t stop.

Author: Monyo in cowhide sauce

Talk a few words

Hello ducks, I am a cowhide sauce that loves life. I am keen to share the pits I stepped on and the weeds I pulled out. I hope my sharing can help the treasures, and I will not get lost!

The Dragon Boat Festival is coming soon. Has everyone eaten zongzi? All my friends who are familiar with me know that I am a real foodie, and I started to eat zongzi before the festival. No, I bought a lot of rice dumplings with novel tastes with the idea of early adopters. Before the Dragon Boat Festival, let’s share the taste and taste of these novel zongzi, and which one is the best.

1 Sanquan Jasmine Longjing Zongzi/Rose Black Tea Zongzi

This is a new Chinese zongzi produced by Sanquan, which has two flavors: jasmine Longjing tea and rose black tea. I bought both models. Let’s try them in turn. The weight of a single package is 200g, and each package contains 4 zongzi, which is equivalent to each zongzi with 50g of zongzi leaves. It belongs to a very mini small zongzi.

Jasmine Longjing zongzi is selected from Hangzhou Longjing and Yunnan Jasmine as the main raw materials. When the leaves of zongzi are opened, you can see that the zongzi has the faint natural green color of Longjing tea, rather than the green and transparent sense of science and technology on the packaging. Jasmine petals can also be seen in glutinous rice, and the stuffing inside is jasmine stuffing, which smells full of flower fragrance and tea fragrance. In one bite, jasmine fragrance, Longjing tea fragrance and zongzi leaf fragrance are mixed together, and the taste is very fresh and the sweetness is just right. It tastes like a dessert without the greasy feeling of traditional zongzi at all.

The raw materials of rose black tea dumplings are black tea and Yunnan roses. When you open the leaves, you can see that the appearance of dumplings is also natural light red and black, and it smells full of tea and roses. Some rose petals can be seen in the rose stuffing inside. The fragrance of roses, zongye and black tea is integrated into one, like a delicate Soviet-style sweet spot, but it is not too sweet, but just right.

2 Wufangzhai Zi Nuo Li Rong Zongzi

Wufangzhai is the representative brand of Jiaxing Zongzi. I believe many friends have eaten his egg yolk pork dumplings, ribs dumplings, big meat dumplings and so on. Not long ago, I just brushed this purple glutinous chestnut dumpling. I haven’t eaten it before. I took advantage of the festive atmosphere this year to taste it. This zongzi belongs to the standard zongzi size, with a single zongzi of 100g.

Zongzi is mainly composed of glutinous rice and purple glutinous rice. It seems that there is a little more glutinous rice, about 1/3 purple glutinous rice and 2/3 glutinous rice. This zongzi looks unremarkable, but it tastes delicious and chewy, and you can taste the mellow zongzi fragrance with one bite.

The addition of chestnut stuffing is also relatively large. This stuffing is very good, just right in sweetness, and it tastes very delicate. It can’t be stopped after eating. It is highly recommended.

3 Miss Black Sesame Walnut Five Black Grains Zongzi

Missing is a brand that started as a black sesame seed. It also introduced five black zongzi with black sesame seeds and walnuts. This zongzi has a pack of 400g, there are five in total, and the weight of a single zongzi is 80g. But from the appearance, it looks similar to the size of the previous tea brown. It should be that this zongzi has more materials and is thicker.

This zongzi looks completely purple. Besides glutinous rice, there are black rice, black kidney beans, black wheat, black quinoa and walnut kernels. It smells like grains mixed with zongzi leaves and tastes chewy.

The black sesame filling in the middle is the taste of his black sesame paste, which is very sweet but not too sweet. With the taste of miscellaneous grains, it goes straight to the taste buds on the tip of the tongue and can’t stop eating it if you are slapped.

40,000 Shouzhai Panda Bangbangzong

This kind of zongzi is different from ordinary zongzi wrapped in leaves. It is wrapped in a bamboo tube, with beautiful outer packaging and the shape of a national treasure, which is very eye-catching.

Each zongzi occupies a bamboo tube, and the weight given is relatively sufficient. A single zongzi is 180g, which belongs to the big zongzi. A packet of zongzi has four flavors, namely, milk yellow preserved fruit flavor, blood glutinous rice and taro paste flavor, eight-treasure bean paste flavor and yellow rice and jujube flavor.

Zongzi can be put into a bamboo tube and sealed with zongzi leaves, which should make the taste of zongzi more layered, with bamboo fragrance on one side and zongzi leaves on the other.

I presented four long chopsticks and a bamboo stick. I want to poke them out when I eat them. This design is quite interesting.

Of the four flavors, the rice dumplings with the taste of bloody glutinous rice and taro mud are the best. The taro mud is chewy and delicious with the fresh bamboo fragrance. It is simply not too delicious. It is highly recommended. The taste of Babao bean paste is similar to that of traditional zongzi. There is not much added Babao rice, which has little effect on the taste. What can be felt on the tip of the tongue is more the natural fragrance of zongzi and bamboo.

The taste and taste of rice dumplings with milk yellow preserved fruit are not bad. The preserved fruit is filled with a lot of stuffing, which tastes sweet and soft. Sweetheart lovers should like this taste. The rice dumplings with the flavor of yellow rice and candied dates are very similar to the traditional candied dates in taste and taste, but such a big rice dumpling with only one candied date is a bit not full of flavor, and it tastes more like the taste of alkaline rice dumplings, which I personally feel is average.

5 wonderful durian ice dumplings/mango ice dumplings

This kind of ice-covered zongzi has two flavors, mango and durian. It’s called zongzi, but it’s actually not a traditional zongzi. Just like the ice-covered moon cake, it’s ready to eat without cooking, so it’s very convenient to eat. Of course, it should be better if it’s iced.

Let’s take a look at the mango ice dumplings first. Its skin is transparent, and you can directly see the mango stuffing inside. When eaten alone, it is tasteless, but it is chewy. How can I put it? This taste is not bad.

The mango stuffing inside is rich in flavor, waxy and slightly sweet, but it is barely acceptable to eat with tasteless ice skin. This kind of stuffing is a bit like Zanba, and friends who like sweets should like it.

Durian ice dumplings are basically the same in appearance except for different fillings, and they are also wrapped with very chewy ice skin.

Personally, the taste and mouthfeel of durian stuffing are better than mango stuffing, and the taste is fuller. If you eat durian in one bite, you can try it boldly.

6 Sam stock black truffle cloud leg dumplings

The last finale is Sam’s soup with black truffles and cloud-legged zongzi. This zongzi is mainly flavored with soup with black truffles. It belongs to salty zongzi, with a single weight of 110g.

At first glance, the materials used in this zongzi are absolutely solid, including pork belly, lotus seeds, ham, egg yolk, black truffles and some fungi. It feels like a zongzi that integrates many delicacies. The addition of broth and black truffles makes this zongzi smell very fragrant, which makes people want to eat it right away.

It tastes very layered, and it combines the flavors of various delicacies. It smells so fragrant that there are no friends. I want to eat a second bite after eating one, and I can’t stop. If you like salty meat zongzi, try this zongzi, and it will definitely satisfy your appetite.

summary

These are the novel dumplings I shared this time. No matter whether they are sweet or salty, the taste is not bad. If you are tired of eating traditional dumplings, you can buy some and try them, and maybe you can explore a new world of your taste buds. What other novel flavors of zongzi have you eaten? Welcome to share in the comment area.

This article comes from what is worth buying website (www.smzdm.com).

The comedy animation "League of Bad Guys" burst into laughter and Awkwafina joined the dubbing.


1905 movie network news A few days ago, the animated comedy film released its first preview, and DreamWorks’ much-anticipated brand-new animated IP unveiled its mystery! The film is based on the best-selling comics in the world. The senior animator of the series first directed the tube, the ace producer made a heavy effort, and the dubbing stars were shining. The Emmy winners of the Golden Globe Awards gathered to give a voice! This film is scheduled to be released in North America on April 22nd, 2022.


The League of Bad Guys is adapted from the popular comic book of the same name. Its original work has been published in 16 million copies worldwide and has been on the authoritative bestseller list for more than 120 weeks. This time, it is re-presented in the form of a movie, and the "bad guy style" is about to sweep the big screen. In the notice released today, five "bad guys" who commit all kinds of evils — — The handsome pickpocket "Big Bad Wolf", the well-informed safe thief "Greedy Snake", the calm and calm camouflage master "Beautiful Belly Shark", the irritable thug "Piranha" and the glib hacker expert "Hacker Spider" appeared on the scene. They are the most notorious "bad guys alliance" and have committed numerous robberies over the years. However, as the world’s most wanted gang, it decided to become a model citizen? Is this a deception or a sincere repentance? An unexpected and hilarious hilarious adventure was staged, which can be said to be full of expectations.


It is worth mentioning that the behind-the-scenes lineup of this film is very strong. Director Pierre Perifil is famous in the industry for his participation in the animation production of Kung Fu Panda series films. In addition, he also served as an animator for Shrek 4 and other films. In 2019, the animated short film "Rabbit Ear Bag Beaver" directed by him was shortlisted in the top 10 best animated short films of Oscar. Damon Ross and Rebecca huntly, the gold medal producers of DreamWorks, are escorting the film. They have been engaged in the development and production of many animations such as The Boss Baby’s Magic Hair Elf, which can be described as rich experience. In addition, the dubbing lineup of this film is also worth looking forward to. Many powerful actors, such as Oscar for Best Supporting Actor, Golden Globe Award for Best Actress in Movies-Musical Comedy, and Emmy Award for Best Supporting Actress in Comedy Series, poured their hearts out. They have different styles, but they cooperated seamlessly. The regrouping of the "Bad League" will surely bring a wonderful story of ups and downs, laughter and tears.


In addition, as a brand-new IP of DreamWorks, this film is not limited to the original, but has been re-created on the basis of inheriting the iconic elements in the book, as director Pierre Perifil said: "We have built a new story, but we are still faithful to the characters and related experiences in the original." Impressively, in the preview, the cool racing scene and the fierce action drama can be described as very eye-catching. In order to create the most distinctive picture, the film draws a lot of inspiration from animated films from different countries, and combines the action scene with the humorous interest in character design and animation style, and finally presents a happy and charming effect. The director bluntly said: "Our action scenes in this movie are very special, and you will never forget them!"


In 2022, "League of Bad Guys" will be released with laughter, so stay tuned!


The cards are full! Xiaomi became a partner of CCTV’s "All-ecological Strategy for People and Cars"

It is reported that Xiaomi has reached a strategic cooperation with the Central Radio and Television General Station and has become a strategic partner of CCTV’s "People, Cars, Home and Ecology", which is the first such cooperation in China.

In addition, Xiaomi was awarded the title of "CCTV Brand Power Project" by CCTV, becoming the second technology enterprise after Huawei.

Previously, CCTV News reported many times on Xiaomi’s scientific and technological innovations, including Xiaomi’s OS, the manned space launch of Shenzhou 16 and the construction of the first large domestic cruise ship.

Xiaomi 澎湃 OS is an operating system focusing on cross-end interconnection and artificial intelligence implantation, which is "the whole ecology of people, cars and homes". Its cross-layer "HyperConnec" breaks the barrier between devices and realizes unified connection protocol and real-time communication.

澎湃 OS also supports cross-end Zhilian, which enables devices to work seamlessly through dynamic real-time networking and integration of device centers. Xiaomi SU7 will be equipped with 澎湃 OS to realize seamless linkage between cars and mobile phones.

In addition, Xiaomi Mijia equipment can also get on the bus without feeling, realize seamless management and use on the big screen of the car, and create an intelligent travel experience of the Internet of Everything.

The 2022 "Praise China" online comment contest was officially launched.

Wechat picture _20220428103600.jpg

  Red Net News April 28th(Reporter Wang Heng He Qing Photography Li Changhong Xu Shijie Li Saifeng) The new era calls for new actions and a new journey to write a new chapter. In order to welcome the 20th Party Congress, on the morning of April 28th, the 2022 "Praise China" online comment contest with the theme of "New Era, New Journey and New Youth" was officially launched in Changsha, Hunan Province, and entries were collected for the whole country.

  The event was jointly sponsored by the Network Communication Bureau of the Central Network Information Office, the Network Social Work Bureau of the Central Network Information Office, the Ideological and Political Work Department of the Ministry of Education, and the Propaganda Department of the Communist Youth League Central Committee. It was hosted by the Network Information Office of Hunan Provincial Party Committee and implemented by Hunan Hongwang New Media Group. The purpose of the activity is to further promote the high-quality development of online comments, vigorously carry forward the main theme of the times, spread the positive energy of the network, lead the majority of netizens to share the same fate with the motherland, and further unite the majestic power of unity and forge ahead, so as to create a good online public opinion atmosphere for the party’s twentieth victory.

  Yang Haodong, member of the Standing Committee of Hunan Provincial Party Committee and Minister of Propaganda Department of Hunan Provincial Party Committee, announced the official launch of the contest.

  According to the organizer of the contest, online comments are an important part of Internet content construction, which is related to the clear cyberspace. It is necessary to strengthen ideological guidance and guide the public opinion to the ballast stone; Focus on rallying people’s hearts and draw concentric circles of struggle and forge ahead; Sharpen patriotic feelings and sublimate the new "sound" state of patriotic expression; Adhere to integrity and innovation, and create a new hotspot for creative expression. It is necessary to inspire and guide young people with great achievements in the new era, and give play to the communication advantages of new media to attract and unite young people. It is expected that netizens will actively participate in the contest, eulogize the times and cheer for the people.

  The contest welcomes the participation of the vast number of online commentators, especially young authors, and looks forward to launching a large number of masterpieces and discovering and cultivating more outstanding online commentators.

  The collection scope of the contest works includes online commentary works that meet the requirements of the contest collection and have not been publicly released, and online commentary works that have been publicly released on various websites and platforms in China from August 1, 2021 to June 30, 2022. Individuals can participate in the competition independently, or they can be recommended by party and government organs, enterprises and institutions, media websites and social organizations. After the collection of works, expert judges will be organized to carry out multiple rounds of evaluation, and 100 outstanding works, 300 finalists and 30 outstanding organizational units will be selected from the entries.

  At the launching ceremony, responsible comrades of the Network Communication Bureau of the Central Network Information Office, the Department of Ideological and Political Work of the Ministry of Education, and representatives of relevant experts and commentators delivered speeches by video. Responsible comrades of relevant departments in Hunan Province and representatives from the media attended the launching ceremony.

  According to the activity arrangement, April 28th to June 30th, 2022 is the time for collecting works, and the contestants and units can submit their works through official channels such as official website (https://hpzg.rednet.cn).

  [News link]

  New era, new journey, new youth

  2022 "Praise China" Online Comment Contest Solicitation Announcement

  In order to effectively promote the high-quality development of online reviews, vigorously carry forward the main theme of the times, spread the positive energy of the network, and more unite the majestic power of forging ahead, the 2022 "Praise China" online review contest was officially launched, and now the entries are collected for the whole country.

  I. Theme of the event

  New era, new journey, new youth

  Second, the organization

  Organizers: Network Communication Bureau of the Central Network Information Office, Network Social Work Bureau of the Central Network Information Office, Ideological and Political Work Department of the Ministry of Education, and Propaganda Department of the Communist Youth League Central Committee.

  Organizer: Network Information Office of Hunan Provincial Party Committee

  Executive unit: Hunan Hongwang New Media Group

  Third, the direction of collection

  Guided by the Supreme Leader’s Socialism with Chinese characteristics Thought in the new era, around the historic achievements and changes in the development of the party and the country in the new era, combined with the reform and innovation practices in various industries and fields in various places and the great changes in people’s production and life, we face up to concerns and make rational comments, and deeply explain the great advantages of the party’s leadership and the Socialism with Chinese characteristics system through empathetic perspectives, profound and unique thinking and warm strokes. Vividly interpret the theoretical logic and practical logic behind extraordinary achievements and happy life, and vividly present the surging weather of the motherland’s galloping development and the prosperous times of Chinese children.

  Fourth, the collection time

  April 28th to June 30th, 2022.

  V. Scope of solicitation

  1. Publicly released works: online review works that were publicly released on various websites and platforms in China from August 1, 2021 to June 30, 2022 and met the requirements of the contest collection.

  2. Unpublished works: online commentary works that meet the requirements of the contest and have not been publicly released.

  Sixth, the collection method

  The declared works include three categories: text comments, video comments and comic comments, which were collected online through the contest in official website (https://hpzg.rednet.cn).

  1. Self-declaration: individuals can declare and upload their own works through online collection channels, and the number of works in the same category should not exceed 3.

  2. Organization declaration: Party and government organs, enterprises and institutions, media websites, social organizations, etc. can declare and upload works by organizing recommendation through online collection channels, and each unit recommends no more than 20 works. When submitting, you need to attach a scanned copy of the organization recommendation letter stamped with the official seal of the unit.

  VII. Solicitation requirements

  1. Correct orientation, profound conception, clear viewpoint, rigorous logic, fluent expression and seeking truth from facts;

  2. Innovative discourse forms and presentation forms, which are suitable for network communication and have strong appeal and communication power;

  3. For literary works, it is required that the long review articles should not exceed 3,000 words and the short review articles should not exceed 1,200 words; Video works require ordinary video to be within 8 minutes, short video to be within 3 minutes, and the format is MP4 and MOV, not exceeding 800 m; Random review works require cartoons to express opinions, pictures with short text explanations, etc., in JPG; format;

  4. All works must be copyright-free, and the contestants agree to authorize the organizers of the competition to use the rights of reproduction, information network dissemination, adaptation and assembly of the entries.

  Eight, award setting

  1. 100 outstanding works (including about 60 works of words, 30 works of videos and 10 works of random comments);

  2. 300 short-listed works (including 180 works of words, 90 works of videos and 30 works of random reviews);

  3. 30 outstanding organizational units.

  IX. Activity Flow

  1. Start the solicitation. The 2022 "Praise China" online comment contest was launched in the whole network, and the channels for submitting works were opened for online collection.

  2. Qualification review. Take a combination of technology and labor to remove works that do not meet the requirements of applying for qualification, and form a preliminary evaluation list.

  3. Preliminary evaluation. According to the evaluation rules, the Preliminary Evaluation Committee selected 1000 works to form a re-evaluation list.

  4. Re-evaluation. The Re-evaluation Committee selected 300 works according to the evaluation rules, and after verifying the authenticity of the declared information, a final evaluation list and a shortlist of works were formed.

  5. Final evaluation. The final evaluation committee selected 100 outstanding works and 30 outstanding organizational units according to the evaluation rules, and publicized them through the contest in official website.

  6. Release the results. Hold the release ceremony of the results of the 2022 "Praise China" online comment contest.

  The right to interpret the activities of this contest belongs to the organizer.

Ten Questions about Pfizer COVID-19 Vaccine

This article comes from WeChat WeChat official account:CC weekly (id: cancer-weekly), Author: Zhang Yujiao (tenured professor of The University of Texas MD Anderson Cancer Center), original title: "Exclusive | These five groups of people cannot be vaccinated! Chinese scholars analyze the top ten problems of Pfizer vaccine, with the title from vision china.

Core summary

1. On the 10th local time, the US Food and Drug Administration(FDA)With 17 votes in favor, 4 votes against and 1 abstention, COVID-19 Vaccine Group decided thatThe benefits of using Pfizer /BioNTech COVID-19 vaccine in adults aged 16 and over outweigh the known risks, and the COVID-19 Vaccine Team of FDA recommended that Pfizer’s COVID-19 vaccine be approved.This means that the last obstacle has been cleared before the COVID-19 vaccine goes on the market in the United States.

2. The vaccination effect of tumor patients receiving chemotherapy and radiotherapy and patients undergoing bone marrow and organ transplantation needs to be studied. People who have been infected should also be vaccinated, but it is not recommended for pregnant women to be vaccinated. Patients with a history of severe allergies should also be carefully vaccinated.

3. At present, it can only be concluded that COVID-19 vaccine is valid for more than half a year.As for how long, we have to wait for the data to speak. According to the current state(Including the titer and maintenance of antibodies in early studies)It may be a year or so, I hope it will be longer.

4. The extent to which COVID-19 vaccine can reduce the chance of spreading virus after vaccination needs further study. Therefore,After vaccination, you need to wash your hands, wear a mask and be socially isolated.

On December 8th, the world’s first Pfizer COVID-19 mRNA vaccine was inoculated in the UK after the third phase clinical study confirmed its effectiveness. The 90-year-old lady told the media at the vaccination site with a strong British accent: "This is the best thing that has happened to me, both effective and free!" . The second vaccinator is an 80-year-old man. His name is William Shakespeare, and he has the same name as the great British writer.

On the same day, after three weeks of investigation, FDA issued a review statement: Pfizer vaccine has no safety concerns, and the effective rate can reach 52% after the first vaccination, and the effective rate will rise to 95% after the second vaccination, and the vaccine can significantly reduce the number of critically ill patients. FDA(US Food and Drug Administration)Decided to submit it to the expert Committee on vaccine efficiency and safety outside the FDA for public hearing, and the whole hearing will be broadcast live on national television.

By 30 FDA independent committees on vaccine efficiency and safety(composed of vaccine experts, doctors and representatives of the public)The hearing will be held from 9: 00 am to 5: 45 pm on December 10, US Eastern Time and December 11, Beijing Time.(Tubing, live broadcast by Twitter). Members of the Committee reviewed tens of thousands of pages of information in advance. After a heated debate, 17 votes in favor and 4 votes against the emergency use of Pfizer mRNA COVID-19 vaccine for adults over 16 years old.

At the hearing, Pfizer released detailed data for the first time. People over 16 years old, including those over 55 years old, have chronic diseases.(including heart and lung disease, cancer history)Those who have a history of HIV, HBV infection but have been controlled are all enrolled in the third phase of the study.

About side effectsMild to moderate discomfort at the inoculation site is very common. Moderate systemic reaction is about 18%, and serious side effects are less than 5%. The research is still going on, and the FDA requires Pfizer to submit updated information to the FDA in January until two years later.

About efficiency95% of the total protection efficiency occurred 7 days after the second inoculation. The protection efficiency of people of all ages and races is above 93%. It has a good protective effect on the history of basic diseases, including cancer.

At the hearing, the safety hazards such as patients with obvious immune deficiency, patients with severe allergic reactions, pregnant women and children were discussed. At the same time, the possibility of transforming mRNA into DNA and reducing the possibility of human-to-human transmission are discussed, and suggestions for future research are put forward, including further research on asymptomatic infected people.

The most controversial issue is whether teenagers aged 16 and 17 can be vaccinated, because there are only more than 100 people in this group in the study.. Some members are opposed to vaccinating teenagers aged 16-17, which is the main reason for voting against it. However, the FDA insists that because many 16-and 17-year-old children in the United States have started working in supermarkets, it is more dangerous.

On December 17th, another mRNA vaccine(Moderna Modena)An FDA hearing will also be held and approval is expected.

After nearly a year of long suffering, people finally saw the dawn. The British media said that "we are vaccinated with hope". However, in the face of more than 1.5 million lives lost around the world, we can’t help but sigh "too late". However, it is worrying that more than 37% of the American people are not willing to be vaccinated at present. They questioned"So soon? Is it safe? !”

Take the United States as an example. Up to now, more than 15 million people in the United States have been infected with COVID-19, and nearly 300,000 people have lost their lives. The second wave of epidemic has just broken out in autumn and winter. Recently, there are 200,000 new cases and more than 2,500 deaths in the United States, far exceeding the first wave in July this year! At this exponential growth rate, if there is no vaccine and effective social isolation, the probability of each American being infected in 2021 will exceed 50%! Each of us should ask ourselves, should we be vaccinated, infected naturally, or locked up at home?The answer is obvious, we have no choice!

At present, nearly one million people have been vaccinated with four vaccines in China. However, the side effects of Pfizer vaccine, such as severe allergy, and whether some immunocompromised people, such as children, cancer patients, organ transplants, pregnant women and AIDS, can be vaccinated, and who can be vaccinated, have also become consistent issues and choices faced by China and the United States. However, the problems encountered in the vaccination of Pfizer vaccine and Modana vaccine in the United States and the United Kingdom will also serve as a reference for the China vaccine that will be widely vaccinated in the future.

First, who will be vaccinated first? What is the final goal?

According to the discussion results of CDC on November 30th, the order of COVID-19 vaccination is as follows:

First batch(From 15 December): frontline medical staff(20 million)And the elderly in nursing homes(millions).

So far, Pfizer will provide 40 million doses of vaccine before the end of the year; Moderna will provide 20 million doses before the end of the year.

Second batch(From January next year)Social necessities, including police, postmen, firefighters, dieters, school teachers, cleaners, food processors, etc.(nearly 90 million). Old people over 65 years old(fifty million).

The third batch: ordinary people(From March next year)It is estimated that more than 100 million people.

The fourth batch: young people and children under the age of 16(From May next year): tens of millions.

MD Anderson medical staff were among the first to be vaccinated. The hospital has subdivided the first batch of personnel:

At present, the Texas government has announced the distribution number of the first batch of Pfizer vaccines in major hospitals. MD Anderson Hospital will receive nearly 5,000 doses of COVID-19 vaccine on the 14th.(two doses for one person), should be able to supply all the clinical medical staff of 1a with vaccination.(The hospital has nearly 1,000 full-time doctors, more than 20,000 full-time employees, and nearly 30,000 people for further study.).

Goal:Strive to reach 70% vaccination rate after June next year, and promote group immunization.(95% effective rate x70% vaccination rate =66.5% immunization rate). In other words, we should stick to wearing masks and social isolation until the end of June next year.(Biden asked people to hold on at least until the end of April). Clear goals, but a long way to go! What should developing countries do if developed countries plan like this?

Figure/COVID-19 vaccine samples developed by Pfizer and BioNTech.

Second, should cancer and other patients with immunodeficiency, or people with severe allergies be vaccinated?

Should cancer and other patients with immunodeficiency, or people with severe allergies be vaccinated? At present, in the third phase of clinical research, tumor patients receiving chemotherapy and radiotherapy, or patients with bone marrow and organ transplantation, HIV, etc., are not allowed to participate in the study because of potential immunosuppression. Therefore, the effect of these patients after vaccination is still a research problem. Related research is being prepared.Generally speaking, if radiotherapy and chemotherapy have stopped for more than one year, cancer patients can consider vaccination.

In addition, two cases of obvious allergic reactions occurred in the population vaccinated in the first week in Britain. Therefore,Experts warn patients with a history of severe allergies to be carefully vaccinated.

3. Should children and pregnant women be vaccinated?

In the current clinical study, neither pregnant women nor children under 12 years old were enrolled. Therefore,Vaccination for pregnant women is not recommended at present. As for teenagers and children(under 16 years old)No further data on safety and effectiveness will be available until May next year.

Fourth, should people who have been infected with COVID-19 be vaccinated?

For people who have been infected,Because the recently reported cases of secondary infection and natural immunity may only last for 3 to 6 months, and the immunity produced by natural infection is weak, they should be vaccinated.

5. How long can immunity last after vaccination?

Since most of the third phase of vaccine research began in July this year, the longest observation time is less than half a year. Therefore, we can only conclude that the validity period is more than half a year at present. As for how long, we have to wait for the data to speak. According to the current state(Including the titer and maintenance of antibodies in early studies)It may be a year or so, I hope it will be longer.

6. After vaccination, will it spread the virus to others? Do you still need to wash your hands, wear a mask and be socially isolated?

At present, the effective rate of mRNA vaccine is 95%, which means that the difference between the number of patients with symptoms accounts for the percentage of the number of patients with symptoms in the control group compared with the random control group that did not receive the vaccine. This is a standard algorithm widely accepted by epidemiology, and it is also a standard index of vaccine listing in the international community, not an invention of a manufacturer. Both Pfizer and Mardner’s vaccine trials rely on patients’ self-reports, and subsequent confirmation tests will only be conducted if there are related symptoms. Therefore, this calculation does not include asymptomatic patients; Secondly, the difference between the two groups in transmission to others has not been detected yet.

Can the vaccine reduce the chance of transmission to others? Scientifically, it should be, but the degree needs further study. Therefore,After the vaccination, it is not necessary to wash your hands, wear masks and be socially isolated. Let’s stick to it for a while and wait for further data.Moreover, the vaccine is not 100% effective, in case you belong to the 5% ineffective population!

Figure/Relevant data of Pfizer vaccine

7. How many times should I be vaccinated? What are the side effects?

Current vaccines all requireInoculate twice. If you only plant it once, the effect will be greatly reduced. Moreover, there must be an interval of three weeks between two times.(Pfizer)Or around.(Mardner). At the same time, the vaccine from the same manufacturer must be vaccinated, even though they are all mRNA vaccines.

As for the side effects, it is a three-point poison. It is an ideal to cure all diseases without side effects; More accurately, it is a fantasy; Be strict, it’s nonsense!

This year, according to the recommendation of CDC in the United States, I have been vaccinated against influenza.(once a year, inactivated vaccine)And herpes zoster vaccine.(Protein vaccine, over 50 years old, administered twice). COVID-19 vaccine is expected to be vaccinated in late December. I don’t have much discomfort after getting the flu vaccine. However, every time I have been vaccinated with herpes zoster vaccine, I have intermittent fever for more than 24 hours, and sometimes fever also causes my whole body to tremble, and my arm is red, swollen and painful for nearly a week. However, I know that these are normal phenomena and belong to mild and moderate side effects.

Based on the available data, most of the side effects of COVID-19 vaccine last for 1-2 days. Common injection site pain, erythema/redness, or fatigue.(Moderna)9.7%, Pfizer(Pfizer)3.8%, fever, chills, muscle aches( Moderna)8.9%, joint pain(Moderna) 5.2%, headache (Moderna)4.5%, Pfizer(Pfizer) 2%。

Long-term side effects need to be followed up in the fourth phase after marketing.

Judging from the information released,MRNA vaccine appears severe(three degrees)The side effect was severe fatigue, accounting for 3.7%. Overall, it is very safe.Mild and moderate discomfort similar to a cold is very common and normal. Please be patient!

Figure/After the first vaccination, patients will get a card to remind them to get the second vaccination on time.

8. Will the new virus mutation affect the effectiveness of the vaccine?

The answer is possible. For example, the mutation rate of influenza virus gene is high, so a new vaccine against influenza in that year should be vaccinated every year. And AIDS has always been because the virus mutates too fast, so far there is no vaccine.

Fortunately, according to the current epidemiological survey, Nature Communications magazine published an article in November this year to study 46,000 cases of COVID-19 virus from different periods around the world, and found that the probability of COVID-19 mutation is relatively low because of its unique proofread inspection mechanism, which is undoubtedly the gospel of the vaccine. At the same time, the mRNA vaccine can be modified according to mutation and then reproduced, which is much easier to operate than the terminal protein vaccine. For example, the gun has been built, just need to modify the structure of the warhead.

9. Why should vaccine storage be at MINUS 70 degrees?

Pfizer vaccine needs to be stored in a freezer at MINUS 70 degrees Celsius for a long time, and it can only be stored in a refrigerator at 2 ~ 7 degrees Celsius for 5 days. Moderna vaccine can be stored for a long time in the freezer at MINUS 20 degrees, and can be stored in the refrigerator at 2 ~ 7 degrees for one month. The reason why RNA is sensitive to temperature is that it is easy to degrade with the increase of temperature. Moderna vaccine is relatively thermotolerant, which may be related to the composition and structure of its lipid carrier. This partly explains that the side effects of Moderna vaccine seem to be a little high.

AstraZeneca’s vaccine is an adenovirus strain, which requires lower temperature and can be stored for half a year at 2 ~ 7 degrees. And is suitable for developing countries.(Note: Freund’s temperature F is used in American charts). However, the comprehensive effective rate of AZ vaccine is about 70%. Subgroup analysis showed that the effective rate of the first low dose group was 90%. However, because this group of people is young.(under 50 years old)And it is not designed in advance. Therefore, it is recognized by the industry as 70% efficient.

Photo/Pfizer is building a "frozen farm" the size of a football field to store vaccines in Kalamazoo, Michigan. Pfizer’s vaccine must be stored below the ultra-low temperature of 70 degrees.

X. Why do Britain and America prefer mRNA vaccine?

On December 2nd, Britain took the lead in approving Pfizer’s vaccine and started vaccination on the 8th. Today, the vaccine has also been approved in the United States, and it is expected to start nationwide vaccination on the 15th. On the 17th of next week, the FDA of the United States is very likely to approve the mRNA vaccine of Moderna, and it is possible to start vaccination on the 22nd. Apart from the fact that these two viruses first completed the phase III clinical randomized study, what factors made the world look at the mRNA vaccine with new eyes?

Thirty years ago, I transferred from tumor immunology research to a brand-new field of tumor gene therapy. At the MD Anderson Cancer Center in the United States, my colleagues and I spent seven years constructing a retrovirus, adenovirus and nanoliposome-mediated anti-cancer gene transformation mode and animal tumor model, which not only contributed to the first patient’s cancer gene therapy in human history, but also made a Nasdaq-listed company. I have published more than a dozen papers myself, won two patents for gene therapy, and obtained a doctorate in tumor biology within four years. After that, I decided to return to the clinical front line and started five years of standardized training for clinical oncology residents.

Retroviruses have the longest gene transformation rate and maintenance time, but unfortunately they will be integrated into the DNA of human hosts. Some scholars are worried about the possibility of cancer. At present, this gene transformation method has been rarely used in cancer treatment.

Adenovirus will not be integrated into human DNA, but it is toxic to cells and will cause immunity to adenovirus vectors. This may explain the side effects of AstraZeneca COVID-19 adenovirus vector vaccine and the change of the initial dose to the effective rate.The high dose of the first vaccination may stimulate a stronger immune response against adenovirus vector, which may affect the results of the second vaccination. Therefore, it is better to use a low dose for the first time).

However, nanotechnology liposome itself has little influence on the immune system, and the general mRNA will not be reverse transcribed and integrated into human DNA, but it will express the protein to be transmitted in human cells for a short time.(For example, COVID-19 spinous protein activates the immune response and then gradually subsides), the best security. However, I used DNA plasmid at that time; Because DNA is much more stable. At that time, everyone knew that RNA extraction and preservation were very difficult, and there was no precedent for successful transformation of mRNA gene.

Gene transfer with COVID-19 spinous protein mRNA as the main body mediated by lipid carrier can avoid errors and potential side effects in the process of DNA transcription, so that spinous protein can be efficiently expressed in human cells in a short time, and the immune response of the body can be activated, which can produce specific antiviral antibodies and immune killer cells more effectively than natural infection. Although the gene expression is short-lived, activated B cells and T cells have their own memories, which can destroy or inhibit the virus for a long time. At the same time, this mRNA will not reverse transcribe into DNA, and will not be integrated into the host DNA, which is safe and reliable.

For decades, the method of mRNA gene transfer has been a dream of scientists. Katalin Kariko, the founding partner of Moderna, the inventor of mRNA technology and a Hungarian-born American scientist, has been on the bench for 40 years, and was originally prepared to set up Moderna to engage in mRNA cancer vaccine. As a result, a Cheng Yaojin COVID-19 was killed halfway.

When scientists in China announced the gene sequence of COVID-19 on January 10th this year.(including spinous process protein)Later, the researchers in the United States and Germany changed hands, but they were unwilling to plant flowers and flowers. Fortunately, this spinous protein was finally proved to be a good immunogen of COVID-19, and COVID-19 mRNA vaccine appeared on the scene. This is an important breakthrough in human science and technology, and it is also the result of the joint efforts of scientists from all over the world.

In contrast, inactivating virus vaccine is a mature method, and this traditional method is adopted in the annual influenza vaccine. Its research and development success rate is high, so it is widely used. However, it is difficult to control the temperature during inactivation, which brings some difficulties to quality control. Therefore, the production capacity is limited. At the same time, the added chemicals will also bring some side effects.

Generally, the effective rate of inactivated influenza vaccine is between 50% and 70%. At present, the early toxicity and antibody positive rate of domestic COVID-19 vaccine with inactivated vaccine as the main body and adenovirus vector have been reported. Volunteers can tolerate mild and moderate side effects, and the antibodies are positive after injection. However, positive antibody does not guarantee that it has sufficient protection. The effective rate must be obtained in the three-phase randomized study with control group. Because the epidemic situation in China is well controlled, the corresponding research must be carried out in other countries with high incidence.

Up to now, the epidemiological efficiency of the strict phase III clinical randomized study of vaccines in China has not been reported, and the world is eagerly awaiting it. I believe the final conclusion will be heard in the near future.The advantages of inactivated vaccine and adenovirus vector vaccine are that they are less affected by temperature, easy to store and transport, and more suitable for developing countries.

Due to the potential advantages of technological innovation and high antigen purification and expression, such as improving vaccine efficiency and productivity and reducing side effects, when the effective rate of mRNA COVID-19 vaccine reached 95%, the industry unanimously hailed this major breakthrough. More importantly, there are almost no seriously ill patients among the vaccinators.

Many people think that this is the arrival of God’s grace! Developed countries such as the United States and Britain have booked the products of these two companies in advance. China’s Fosun Company also signed a cooperation agreement with Pfizer and has completed the first phase of clinical trials. It is expected that the related Phase 2 will be launched in China soon.(Non-random)Clinical research to obtain the approval of China FDA.

Figure/A nurse and patient in California. In many parts of the United States, the pressure on the health system has been overwhelmed and is on the verge of collapse at any time.

Although American health insurance and the government will pay the cost of vaccination, another difficulty is that more than 37% people in the United States are not at ease with the vaccine and are not prepared to vaccinate immediately. In this regard, three former presidents of the United States, Bush, Clinton and Obama, said that they would vaccinate under the observation of the media at the first time as a platform for vaccine safety.

Because the vaccine is for normal people, it is not a "medicine", not to treat patients, but to prevent diseases. Meanwhile, for COVID-19 vaccine, the population to be vaccinated is billions of healthy people, including children.Therefore, its safety must be much stricter than that of "medicine".Therefore, if time is not pressing, all new vaccines should wait for a long time.(more than 2 years)The data will be finally approved. But in the face of a serious epidemic, this is irrational. The regulations that allow emergency use are designed for this situation.

At present, FDA requires that the last patient should be observed for at least 2 months after entering the Phase III clinical study to ensure that there are no serious acute side effects. Moreover, regulators must strictly control the use of these new vaccines from the beginning. The initial use of these vaccines is limited to those who need them most-doctors, nurses, other health care workers, and the elderly in nursing homes. Regulators also need to continue to closely monitor the side effects of vaccines already on the market.(so-called Phase IV Clinical Study). With the accumulation of data in the first two months of next year, the range of vaccinators will be further expanded.

The development of human society always strives for survival first, and then for improvement and perfection.

When the hopes of the whole world are pinned on the COVID-19 vaccine, the hardest work has just begun. We know that the best antiviral function of the vaccine will not be realized until two weeks after the second vaccination.In other words, for most people, December this year, January and February next year will be the darkest moments in the medical history of the United States since the Spanish influenza pandemic in World War I.

According to Dr. Fauci, director of the Institute of Infectious Diseases of the National Institutes of Health, it is estimated that by March next year, about 500,000 people in the United States will die in COVID-19, surpassing the number of deaths in World War II in the United States.(about 400,000). Regrettably, some people in the United States still refuse to wear masks and social isolation. Up to now, 37% people are skeptical about vaccines, and the epidemic prevention work has a long way to go!

Controversy over vaccines(Inoculation or non-inoculation, domestic or imported)The reason and background are very complicated, and it will not stop for a while. As a scientist and a doctor, I care most about yourself! Vaccinate, not only for others, but also for yourself!


This article comes from WeChat WeChat official account:CC weekly (id: cancer-weekly), Author: Zhang Yujiao (tenured professor of The University of Texas MD Anderson Cancer Center)