The Biography of Naruto Bo Ren: A New Endurance Attack: A Review of the Flashy Endurance Stewing.

  Biography of Naruto: New Endurance Attack is a brand-new attempt of Naruto IP, which is different from the extreme storm series that is good at telling stories and performing effects. Naruto: New Endurance Attack focuses on online PVP. In this game, online battle of 4V4 is the main gameplay. Players compete with other players in different modes by teaming up, thus improving their level and dominating Endurance League. The biggest selling point of this game is the powerful customization system. Players will no longer play the role in the original, but create a unique "ninja" by customizing ninja, equipment and image. This also allows it to distinguish itself from the extreme storm series.

  However, this insurmountable "mountain" is undoubtedly a difficult challenge for "Huo Ying: New Endurance Attack". From the previous preview, the first impression of the game is very profound, and the customized system with strong plasticity in 4V4 online battle has successfully attracted the attention of the original fans. Then, can "Huo Ying: New Endurance Attack" carry forward this IP on the road of the game like the extreme storm series?

Wandering stars
The scene between Naruto and Sasuke is as bad as the scene where Batman’s parents died.

  The story of "Huo Ying: New Endurance Attack" happened after the comic book Endurance World War, when Naruto had become Huo Ying. In order to better prevent future wars, Konoha organized a Endurance World League with other villages. The player is a contestant and comes to Muye Village to participate in the competition. Different from playing the original role in other Huoying games, in Huoying: New Endurance Attack, with the powerful custom system of the game, players can pinch out unique roles. The advantage of not controlling the original role is that players can participate in the battle in their own capacity, giving players the greatest sense of participation.

  If you read the original, you will find that although there are many options for each part, most of them actually split the characters’ faces and costumes in the comics for players to choose from. If you don’t like the original role, you can make an identical one according to the role you like.

Wandering stars
From head to toe, clothes to accessories can be customized, and you will often see all kinds of strange and fancy players in the hall.

  The custom system of the game is not limited to the shape of the character, but can be reflected in the "avatar system" of the game. You can understand this system as a profession. Players decide their own role attack methods according to four basic types. Of course, you can switch at any time in the subsequent battles.

  Avatars are mainly divided into attack, defense, shooting and healing. In fact, you can put them in the right place with other basic occupations that are common in online games. Attack is good at melee output, shooting is good at remote output, and most skills of defense are defensive. The more you play an auxiliary role in the team, the more you are a wet nurse, which can support your teammates. Each battle consists of a team of four players. Although theoretically speaking, it is reasonable to output one T and one wet nurse according to the matching of occupations, in fact, in this game, attack and shooting have a great advantage in the battle, and teams like 4 attacks, 2 attacks and 2 shots often appear, while Shouheyue rarely sees them play because of their low attack power.

Wandering stars
The skills of the characters are all familiar moves in the original, and they can be combined at will according to different occupations.

  Each class has two main skills and an arcane meaning, and the weapons it can carry are also different according to different classes. It should be noted that the professional customization system is very powerful. As long as the players upgrade their level, the obtained ninja skills can be matched at will. You can either let the characters open eight armor-dodgers and put spiral pills, or you can use them together with Deidara’s explosives.

Wandering stars
Players can worship the characters in comics as masters and learn their unique skills by upgrading their level.

  Of course, the system also provides players with a number of characters in comics. If you are tired of using custom characters, it is also a pleasure to use a set character.

Wandering stars
As a random game, there are only 20 characters in comics available to players at present.

  It should be noted that playing needs to be connected to the internet all the time. It is not easy to play smoothly. Besides having a good network environment, the server is often disconnected and stuck, which has become a "threshold" that hinders players’ smooth experience. At the same time, each battle needs to be matched on the basis of a player’s network. If the owner’s network is not good, the other seven people in the room will be stuck and affect the battle, or they will be kicked out of the room to match again. This situation of being kicked out without rhyme or reason appears very often in the game.

Wandering stars
This is probably the most common interface you see when you experience the game.

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The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition was listed as an honorable pet.

  For human beings, love is an endless topic. What is love? Everyone may have different opinions, but there is no denying that true love is a power to make people better.

  Speaking of cars, people subconsciously think of cold steel and hard-core industries. Euler, a new energy car that loves women more, is committed to being a romantic alien in this industrial world and deeply rooted "love" in the brand gene.

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image001

  On August 20th, Euler Auto "Better for Love", together with many online and offline users, witnessed the launch of the 400,000th complete car of Euler, and the latest achievement created by the brand and users, the 2023 Good Cat & Good Cat GT Mulan Edition, was also listed at the same time, with a limited cash benefit of 129,800! On the same day, it coincided with the fifth anniversary of Euler’s founding. Euler, who grew up with users, not only invited users to visit the park, punch cards and interact, but also linked online users with 8 hours of live broadcast activities to witness the important moment of the brand and share a feast of love.

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image002

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image003

  400,000 love, condensed in a moment: Euler’s 400,000 th car rolled off the assembly line.

  Euler has always regarded users as the first driving force for brand growth. Brands talk to global users with love as the world language, and carry forward the power of "more love" with practical actions.

  Because of "more love", it is loved, and Euler Auto has gained the love of more and more users. In this activity, Euler welcomed the 400,000 th vehicle off the assembly line, and connected directly to Great Wall Motor Taizhou Smart Factory to witness this special Euler good cat driving out of the factory with users. Taizhou factory is the eighth largest vehicle production base built by Great Wall Motor in China and the strategic core of East China market, and is regarded as the "intelligent new engine" of Great Wall Motor’s new energy strategy. Relying on such a high-standard production system layout, Euler continues to provide users with high-quality and high-value automobile products. The automobile products under the brand have fully covered the A0-class to B-class market, which not only created a new category of women’s automobiles, but also gave them a new definition from a new perspective, creating more big items with a better life for women to travel.

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image004

  Perhaps, the weight of love can’t be calculated by numbers, but Euler walks with 400,000 gentle forces with sincerity. In order to break the prejudice of cars against female consumers, Euler broke away from convention and became the first car brand in the world to clearly support women, focusing on the women’s car track. To this end, the Euler brand redefined the women’s track with technology and created the world’s first 1080 women’s safety architecture — — Warm technology makes "female car" not only a marketing amulet, but also a technical moat.

  Because of love, Euler saw the bloom of "genius mother"; Because of love, Euler joined hands with women to run the marathon of life; Because of love, Euler is willing to bend over to be the stage … … Euler firmly stands with women and works with users to build a feminine charm culture, witnessing the vitality, elegance, courage and exquisiteness of contemporary women, so that every bloom has strength. In Euler’s user base, the repurchase rate exceeds 26%, the referral rate exceeds 31%, and the proportion of female users exceeds 75%. The brand is deeply recognized and affirmed by the majority of users. At the same time, today’s Euler has already gone abroad, heading for 87 countries and regions around the world, talking to users around the world with love as the world language, and letting the world see the power of tenderness.

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image006

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image007

  As the leader of the new track for women’s cars, Euler has no fear of becoming a "lone warrior" in the industry. The brand was born in wonder, but also grew up in doubt and created new miracles, which made people see that in the world of cars, there are not only hardcore, parameters and competition, but also tenderness, delicacy and love. The 400,000th vehicle rolled off the assembly line, which means that the Euler brand will soon have 40 copies of support from users. There are 8 billion people in the world, and 400,000 of the 8 billion people may be small, but it is the love from users that makes the Euler brand more emboldened and more confident.

  For the sake of love, the 2023 Good Cat & Good Cat GT Mulan Edition was launched with a limited time cash benefit of 20,000 yuan.

  As early as this year’s Shanghai Auto Show, the Euler brand started the recruitment of "Good Cat Co-creation Officer" and received many valuable suggestions from users in the past four months. The newly listed 2023 Euler Good Cat and Euler Good Cat GT Mulan Edition are the latest achievements created by Euler and users, and they are also the witness of Euler’s love with users.

  Relying on the forest ecological R&D system of Great Wall Motor, Good Cat and Good Cat GT are equipped with the high-performance permanent magnet synchronous motor developed by Great Wall Motor, which is stronger, faster and quieter. While continuing the high quality of "Three Good" cats, the performance of the new car has been improved in an all-round way. It can achieve the maximum power of 135kW and the peak torque of 232N·m, and the acceleration of 0-50km/h takes only 3.5s, which is faster, more energetic and more powerful in the middle section, making it easier for both high-speed driving and urban commuting. At the same time, its maximum climbing degree is increased by 9% to 38%, and it can be more comfortable to go uphill and downhill, so it is possible to travel more when unlocking. Combined with user feedback, the new car has achieved better NVH performance, and can have better quietness when sitting in the car, bringing users a more comfortable and pleasant driving experience.

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image008

  In addition, Euler brand pays attention to young people’s love for exquisite camping. Both Good Cat and Good Cat GT are equipped with V2L external discharge function, and the discharge power can reach 3.3 kW. In the wild, it is easy to use coffee machines, induction cookers, even projectors and other plug-in devices to easily meet the electricity demand of a family camping. Imagine that you can sit around with friends and family under the stars, watch a movie, enjoy a concert, or pick up a long-lost electric guitar and "roar" with your companions, from the city to the countryside, from high-rise buildings to castle peak, just by 2 hours’ drive.

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image010

  In order to better give back to users, Euler brand has launched a cash discount of 20,000 yuan and free installation of charging piles for Good Cat and Good Cat GT! The 2023 Euler Good Cat 401km honorable model, the national suggested retail price is 149,800 yuan, and the price is 129,800 yuan after limited time; The 2023 Euler Good Cat 501km honorable model, the national suggested retail price is 165,800 yuan, and the price is 145,800 yuan after limited time; The 2023 Euler Good Cat GT Mulan Edition is a 401km honorable model, with a suggested retail price of 153,800 yuan nationwide and a price of 133,800 yuan after limited time. At the same time, the subscription users of Good Cat Honor can enjoy the external discharge function of V2L worth 2999 yuan for free; The good cat GT with V2L function has come standard, and you can also choose the intelligent assisted driving optional package at a 50% discount price!

The 400,000th complete car of Euler Auto rolled off the assembly line. The 2023 Euler Good Cat & Good Cat GT Mulan Edition comes on the market _fororder_image011

  Users are always Euler’s precious wealth and the source of power to support Euler’s continuous progress. Insisting on joining hands with users and "creating for love" also makes Euler’s products better and better. Better understanding of the user’s product strength upgrade, more people-friendly prices, and greater concessions are the most authentic feedback from Euler to users.

  From the past to the present, from 0 to 400,000, Euler has been practicing the promise of "more love" with practical actions. Euler brand regards love as a long-term cause and sincerely pays tribute to trust. In the future, Euler will also continue to walk with users, work hard for dreams and career together, and work with thousands of "her" in Qian Qian to love and be better. (Photo: Provided by Great Wall Euler)

Tesla China Model Y" is "worth seeing" another dark horse.

The richness of a car configuration is related to the user’s car experience, so many people are concerned about its configuration today. Not much to say, let’s take a look.

First of all, from the appearance, the front face of Model Y has improved the grade of the whole vehicle and looks very sporty. Coupled with the sharp headlights, the grade of the whole vehicle has been improved. The car is equipped with LED daytime running lights, front fog lights, automatic opening and closing, adaptive far and near light, delayed closing and so on. Come to the side of the car, the car body size is 4750MM*1921MM*1624MM, the car uses sharp lines, giving people a very tough feeling, with large-sized thick-walled tires, giving people a very capable feeling. In terms of the rear end, the overall shape of the rear end echoes the front face, and the taillights give people a very tough feeling, and the shape is avant-garde.

Coming into the Model Y car, the interior of Model Y adopts a simple and generous shape, which highlights the layered effect. The steering wheel of the car is well designed and made of genuine leather, which gives people an impulse to control it. Let’s take a look at the central control, with a 15-inch touch-sensitive LCD central control screen, which makes the interior design quite layered, and the overall design of the central control is remarkable. The dashboard and seats are also eye-catching. The dashboard of this car presents a tough design style and looks very unique. The car adopts leather-like seats, which are wide and thick, improving the riding experience of drivers and passengers.

The Model Y is 357KW, the total torque is 659N.m, and the maximum speed is 250 km/h.

The space performance of the Model Y trunk is OK. If there are large items during the trip, you can put down the rear seats to expand the space. At the same time, the car is equipped with anti-lock braking (ABS), LED daytime running lights, brake assist (EBA/BAS, etc.), braking force distribution (EBD), traction control (ASR/TCS, etc.), main driving airbag, co-pilot airbag, side airbag curtain, front side airbag and other safety configurations.

Do you have the urge to buy a car after reading the whole article? Let me make a summary. This car has been introduced almost before, and I believe many users who buy a car have taken a fancy to its comfort and practicality.

Ten Questions about Pfizer COVID-19 Vaccine

This article comes from WeChat WeChat official account:CC weekly (id: cancer-weekly), Author: Zhang Yujiao (tenured professor of The University of Texas MD Anderson Cancer Center), original title: "Exclusive | These five groups of people cannot be vaccinated! Chinese scholars analyze the top ten problems of Pfizer vaccine, with the title from vision china.

Core summary

1. On the 10th local time, the US Food and Drug Administration(FDA)With 17 votes in favor, 4 votes against and 1 abstention, COVID-19 Vaccine Group decided thatThe benefits of using Pfizer /BioNTech COVID-19 vaccine in adults aged 16 and over outweigh the known risks, and the COVID-19 Vaccine Team of FDA recommended that Pfizer’s COVID-19 vaccine be approved.This means that the last obstacle has been cleared before the COVID-19 vaccine goes on the market in the United States.

2. The vaccination effect of tumor patients receiving chemotherapy and radiotherapy and patients undergoing bone marrow and organ transplantation needs to be studied. People who have been infected should also be vaccinated, but it is not recommended for pregnant women to be vaccinated. Patients with a history of severe allergies should also be carefully vaccinated.

3. At present, it can only be concluded that COVID-19 vaccine is valid for more than half a year.As for how long, we have to wait for the data to speak. According to the current state(Including the titer and maintenance of antibodies in early studies)It may be a year or so, I hope it will be longer.

4. The extent to which COVID-19 vaccine can reduce the chance of spreading virus after vaccination needs further study. Therefore,After vaccination, you need to wash your hands, wear a mask and be socially isolated.

On December 8th, the world’s first Pfizer COVID-19 mRNA vaccine was inoculated in the UK after the third phase clinical study confirmed its effectiveness. The 90-year-old lady told the media at the vaccination site with a strong British accent: "This is the best thing that has happened to me, both effective and free!" . The second vaccinator is an 80-year-old man. His name is William Shakespeare, and he has the same name as the great British writer.

On the same day, after three weeks of investigation, FDA issued a review statement: Pfizer vaccine has no safety concerns, and the effective rate can reach 52% after the first vaccination, and the effective rate will rise to 95% after the second vaccination, and the vaccine can significantly reduce the number of critically ill patients. FDA(US Food and Drug Administration)Decided to submit it to the expert Committee on vaccine efficiency and safety outside the FDA for public hearing, and the whole hearing will be broadcast live on national television.

By 30 FDA independent committees on vaccine efficiency and safety(composed of vaccine experts, doctors and representatives of the public)The hearing will be held from 9: 00 am to 5: 45 pm on December 10, US Eastern Time and December 11, Beijing Time.(Tubing, live broadcast by Twitter). Members of the Committee reviewed tens of thousands of pages of information in advance. After a heated debate, 17 votes in favor and 4 votes against the emergency use of Pfizer mRNA COVID-19 vaccine for adults over 16 years old.

At the hearing, Pfizer released detailed data for the first time. People over 16 years old, including those over 55 years old, have chronic diseases.(including heart and lung disease, cancer history)Those who have a history of HIV, HBV infection but have been controlled are all enrolled in the third phase of the study.

About side effectsMild to moderate discomfort at the inoculation site is very common. Moderate systemic reaction is about 18%, and serious side effects are less than 5%. The research is still going on, and the FDA requires Pfizer to submit updated information to the FDA in January until two years later.

About efficiency95% of the total protection efficiency occurred 7 days after the second inoculation. The protection efficiency of people of all ages and races is above 93%. It has a good protective effect on the history of basic diseases, including cancer.

At the hearing, the safety hazards such as patients with obvious immune deficiency, patients with severe allergic reactions, pregnant women and children were discussed. At the same time, the possibility of transforming mRNA into DNA and reducing the possibility of human-to-human transmission are discussed, and suggestions for future research are put forward, including further research on asymptomatic infected people.

The most controversial issue is whether teenagers aged 16 and 17 can be vaccinated, because there are only more than 100 people in this group in the study.. Some members are opposed to vaccinating teenagers aged 16-17, which is the main reason for voting against it. However, the FDA insists that because many 16-and 17-year-old children in the United States have started working in supermarkets, it is more dangerous.

On December 17th, another mRNA vaccine(Moderna Modena)An FDA hearing will also be held and approval is expected.

After nearly a year of long suffering, people finally saw the dawn. The British media said that "we are vaccinated with hope". However, in the face of more than 1.5 million lives lost around the world, we can’t help but sigh "too late". However, it is worrying that more than 37% of the American people are not willing to be vaccinated at present. They questioned"So soon? Is it safe? !”

Take the United States as an example. Up to now, more than 15 million people in the United States have been infected with COVID-19, and nearly 300,000 people have lost their lives. The second wave of epidemic has just broken out in autumn and winter. Recently, there are 200,000 new cases and more than 2,500 deaths in the United States, far exceeding the first wave in July this year! At this exponential growth rate, if there is no vaccine and effective social isolation, the probability of each American being infected in 2021 will exceed 50%! Each of us should ask ourselves, should we be vaccinated, infected naturally, or locked up at home?The answer is obvious, we have no choice!

At present, nearly one million people have been vaccinated with four vaccines in China. However, the side effects of Pfizer vaccine, such as severe allergy, and whether some immunocompromised people, such as children, cancer patients, organ transplants, pregnant women and AIDS, can be vaccinated, and who can be vaccinated, have also become consistent issues and choices faced by China and the United States. However, the problems encountered in the vaccination of Pfizer vaccine and Modana vaccine in the United States and the United Kingdom will also serve as a reference for the China vaccine that will be widely vaccinated in the future.

First, who will be vaccinated first? What is the final goal?

According to the discussion results of CDC on November 30th, the order of COVID-19 vaccination is as follows:

First batch(From 15 December): frontline medical staff(20 million)And the elderly in nursing homes(millions).

So far, Pfizer will provide 40 million doses of vaccine before the end of the year; Moderna will provide 20 million doses before the end of the year.

Second batch(From January next year)Social necessities, including police, postmen, firefighters, dieters, school teachers, cleaners, food processors, etc.(nearly 90 million). Old people over 65 years old(fifty million).

The third batch: ordinary people(From March next year)It is estimated that more than 100 million people.

The fourth batch: young people and children under the age of 16(From May next year): tens of millions.

MD Anderson medical staff were among the first to be vaccinated. The hospital has subdivided the first batch of personnel:

At present, the Texas government has announced the distribution number of the first batch of Pfizer vaccines in major hospitals. MD Anderson Hospital will receive nearly 5,000 doses of COVID-19 vaccine on the 14th.(two doses for one person), should be able to supply all the clinical medical staff of 1a with vaccination.(The hospital has nearly 1,000 full-time doctors, more than 20,000 full-time employees, and nearly 30,000 people for further study.).

Goal:Strive to reach 70% vaccination rate after June next year, and promote group immunization.(95% effective rate x70% vaccination rate =66.5% immunization rate). In other words, we should stick to wearing masks and social isolation until the end of June next year.(Biden asked people to hold on at least until the end of April). Clear goals, but a long way to go! What should developing countries do if developed countries plan like this?

Figure/COVID-19 vaccine samples developed by Pfizer and BioNTech.

Second, should cancer and other patients with immunodeficiency, or people with severe allergies be vaccinated?

Should cancer and other patients with immunodeficiency, or people with severe allergies be vaccinated? At present, in the third phase of clinical research, tumor patients receiving chemotherapy and radiotherapy, or patients with bone marrow and organ transplantation, HIV, etc., are not allowed to participate in the study because of potential immunosuppression. Therefore, the effect of these patients after vaccination is still a research problem. Related research is being prepared.Generally speaking, if radiotherapy and chemotherapy have stopped for more than one year, cancer patients can consider vaccination.

In addition, two cases of obvious allergic reactions occurred in the population vaccinated in the first week in Britain. Therefore,Experts warn patients with a history of severe allergies to be carefully vaccinated.

3. Should children and pregnant women be vaccinated?

In the current clinical study, neither pregnant women nor children under 12 years old were enrolled. Therefore,Vaccination for pregnant women is not recommended at present. As for teenagers and children(under 16 years old)No further data on safety and effectiveness will be available until May next year.

Fourth, should people who have been infected with COVID-19 be vaccinated?

For people who have been infected,Because the recently reported cases of secondary infection and natural immunity may only last for 3 to 6 months, and the immunity produced by natural infection is weak, they should be vaccinated.

5. How long can immunity last after vaccination?

Since most of the third phase of vaccine research began in July this year, the longest observation time is less than half a year. Therefore, we can only conclude that the validity period is more than half a year at present. As for how long, we have to wait for the data to speak. According to the current state(Including the titer and maintenance of antibodies in early studies)It may be a year or so, I hope it will be longer.

6. After vaccination, will it spread the virus to others? Do you still need to wash your hands, wear a mask and be socially isolated?

At present, the effective rate of mRNA vaccine is 95%, which means that the difference between the number of patients with symptoms accounts for the percentage of the number of patients with symptoms in the control group compared with the random control group that did not receive the vaccine. This is a standard algorithm widely accepted by epidemiology, and it is also a standard index of vaccine listing in the international community, not an invention of a manufacturer. Both Pfizer and Mardner’s vaccine trials rely on patients’ self-reports, and subsequent confirmation tests will only be conducted if there are related symptoms. Therefore, this calculation does not include asymptomatic patients; Secondly, the difference between the two groups in transmission to others has not been detected yet.

Can the vaccine reduce the chance of transmission to others? Scientifically, it should be, but the degree needs further study. Therefore,After the vaccination, it is not necessary to wash your hands, wear masks and be socially isolated. Let’s stick to it for a while and wait for further data.Moreover, the vaccine is not 100% effective, in case you belong to the 5% ineffective population!

Figure/Relevant data of Pfizer vaccine

7. How many times should I be vaccinated? What are the side effects?

Current vaccines all requireInoculate twice. If you only plant it once, the effect will be greatly reduced. Moreover, there must be an interval of three weeks between two times.(Pfizer)Or around.(Mardner). At the same time, the vaccine from the same manufacturer must be vaccinated, even though they are all mRNA vaccines.

As for the side effects, it is a three-point poison. It is an ideal to cure all diseases without side effects; More accurately, it is a fantasy; Be strict, it’s nonsense!

This year, according to the recommendation of CDC in the United States, I have been vaccinated against influenza.(once a year, inactivated vaccine)And herpes zoster vaccine.(Protein vaccine, over 50 years old, administered twice). COVID-19 vaccine is expected to be vaccinated in late December. I don’t have much discomfort after getting the flu vaccine. However, every time I have been vaccinated with herpes zoster vaccine, I have intermittent fever for more than 24 hours, and sometimes fever also causes my whole body to tremble, and my arm is red, swollen and painful for nearly a week. However, I know that these are normal phenomena and belong to mild and moderate side effects.

Based on the available data, most of the side effects of COVID-19 vaccine last for 1-2 days. Common injection site pain, erythema/redness, or fatigue.(Moderna)9.7%, Pfizer(Pfizer)3.8%, fever, chills, muscle aches( Moderna)8.9%, joint pain(Moderna) 5.2%, headache (Moderna)4.5%, Pfizer(Pfizer) 2%。

Long-term side effects need to be followed up in the fourth phase after marketing.

Judging from the information released,MRNA vaccine appears severe(three degrees)The side effect was severe fatigue, accounting for 3.7%. Overall, it is very safe.Mild and moderate discomfort similar to a cold is very common and normal. Please be patient!

Figure/After the first vaccination, patients will get a card to remind them to get the second vaccination on time.

8. Will the new virus mutation affect the effectiveness of the vaccine?

The answer is possible. For example, the mutation rate of influenza virus gene is high, so a new vaccine against influenza in that year should be vaccinated every year. And AIDS has always been because the virus mutates too fast, so far there is no vaccine.

Fortunately, according to the current epidemiological survey, Nature Communications magazine published an article in November this year to study 46,000 cases of COVID-19 virus from different periods around the world, and found that the probability of COVID-19 mutation is relatively low because of its unique proofread inspection mechanism, which is undoubtedly the gospel of the vaccine. At the same time, the mRNA vaccine can be modified according to mutation and then reproduced, which is much easier to operate than the terminal protein vaccine. For example, the gun has been built, just need to modify the structure of the warhead.

9. Why should vaccine storage be at MINUS 70 degrees?

Pfizer vaccine needs to be stored in a freezer at MINUS 70 degrees Celsius for a long time, and it can only be stored in a refrigerator at 2 ~ 7 degrees Celsius for 5 days. Moderna vaccine can be stored for a long time in the freezer at MINUS 20 degrees, and can be stored in the refrigerator at 2 ~ 7 degrees for one month. The reason why RNA is sensitive to temperature is that it is easy to degrade with the increase of temperature. Moderna vaccine is relatively thermotolerant, which may be related to the composition and structure of its lipid carrier. This partly explains that the side effects of Moderna vaccine seem to be a little high.

AstraZeneca’s vaccine is an adenovirus strain, which requires lower temperature and can be stored for half a year at 2 ~ 7 degrees. And is suitable for developing countries.(Note: Freund’s temperature F is used in American charts). However, the comprehensive effective rate of AZ vaccine is about 70%. Subgroup analysis showed that the effective rate of the first low dose group was 90%. However, because this group of people is young.(under 50 years old)And it is not designed in advance. Therefore, it is recognized by the industry as 70% efficient.

Photo/Pfizer is building a "frozen farm" the size of a football field to store vaccines in Kalamazoo, Michigan. Pfizer’s vaccine must be stored below the ultra-low temperature of 70 degrees.

X. Why do Britain and America prefer mRNA vaccine?

On December 2nd, Britain took the lead in approving Pfizer’s vaccine and started vaccination on the 8th. Today, the vaccine has also been approved in the United States, and it is expected to start nationwide vaccination on the 15th. On the 17th of next week, the FDA of the United States is very likely to approve the mRNA vaccine of Moderna, and it is possible to start vaccination on the 22nd. Apart from the fact that these two viruses first completed the phase III clinical randomized study, what factors made the world look at the mRNA vaccine with new eyes?

Thirty years ago, I transferred from tumor immunology research to a brand-new field of tumor gene therapy. At the MD Anderson Cancer Center in the United States, my colleagues and I spent seven years constructing a retrovirus, adenovirus and nanoliposome-mediated anti-cancer gene transformation mode and animal tumor model, which not only contributed to the first patient’s cancer gene therapy in human history, but also made a Nasdaq-listed company. I have published more than a dozen papers myself, won two patents for gene therapy, and obtained a doctorate in tumor biology within four years. After that, I decided to return to the clinical front line and started five years of standardized training for clinical oncology residents.

Retroviruses have the longest gene transformation rate and maintenance time, but unfortunately they will be integrated into the DNA of human hosts. Some scholars are worried about the possibility of cancer. At present, this gene transformation method has been rarely used in cancer treatment.

Adenovirus will not be integrated into human DNA, but it is toxic to cells and will cause immunity to adenovirus vectors. This may explain the side effects of AstraZeneca COVID-19 adenovirus vector vaccine and the change of the initial dose to the effective rate.The high dose of the first vaccination may stimulate a stronger immune response against adenovirus vector, which may affect the results of the second vaccination. Therefore, it is better to use a low dose for the first time).

However, nanotechnology liposome itself has little influence on the immune system, and the general mRNA will not be reverse transcribed and integrated into human DNA, but it will express the protein to be transmitted in human cells for a short time.(For example, COVID-19 spinous protein activates the immune response and then gradually subsides), the best security. However, I used DNA plasmid at that time; Because DNA is much more stable. At that time, everyone knew that RNA extraction and preservation were very difficult, and there was no precedent for successful transformation of mRNA gene.

Gene transfer with COVID-19 spinous protein mRNA as the main body mediated by lipid carrier can avoid errors and potential side effects in the process of DNA transcription, so that spinous protein can be efficiently expressed in human cells in a short time, and the immune response of the body can be activated, which can produce specific antiviral antibodies and immune killer cells more effectively than natural infection. Although the gene expression is short-lived, activated B cells and T cells have their own memories, which can destroy or inhibit the virus for a long time. At the same time, this mRNA will not reverse transcribe into DNA, and will not be integrated into the host DNA, which is safe and reliable.

For decades, the method of mRNA gene transfer has been a dream of scientists. Katalin Kariko, the founding partner of Moderna, the inventor of mRNA technology and a Hungarian-born American scientist, has been on the bench for 40 years, and was originally prepared to set up Moderna to engage in mRNA cancer vaccine. As a result, a Cheng Yaojin COVID-19 was killed halfway.

When scientists in China announced the gene sequence of COVID-19 on January 10th this year.(including spinous process protein)Later, the researchers in the United States and Germany changed hands, but they were unwilling to plant flowers and flowers. Fortunately, this spinous protein was finally proved to be a good immunogen of COVID-19, and COVID-19 mRNA vaccine appeared on the scene. This is an important breakthrough in human science and technology, and it is also the result of the joint efforts of scientists from all over the world.

In contrast, inactivating virus vaccine is a mature method, and this traditional method is adopted in the annual influenza vaccine. Its research and development success rate is high, so it is widely used. However, it is difficult to control the temperature during inactivation, which brings some difficulties to quality control. Therefore, the production capacity is limited. At the same time, the added chemicals will also bring some side effects.

Generally, the effective rate of inactivated influenza vaccine is between 50% and 70%. At present, the early toxicity and antibody positive rate of domestic COVID-19 vaccine with inactivated vaccine as the main body and adenovirus vector have been reported. Volunteers can tolerate mild and moderate side effects, and the antibodies are positive after injection. However, positive antibody does not guarantee that it has sufficient protection. The effective rate must be obtained in the three-phase randomized study with control group. Because the epidemic situation in China is well controlled, the corresponding research must be carried out in other countries with high incidence.

Up to now, the epidemiological efficiency of the strict phase III clinical randomized study of vaccines in China has not been reported, and the world is eagerly awaiting it. I believe the final conclusion will be heard in the near future.The advantages of inactivated vaccine and adenovirus vector vaccine are that they are less affected by temperature, easy to store and transport, and more suitable for developing countries.

Due to the potential advantages of technological innovation and high antigen purification and expression, such as improving vaccine efficiency and productivity and reducing side effects, when the effective rate of mRNA COVID-19 vaccine reached 95%, the industry unanimously hailed this major breakthrough. More importantly, there are almost no seriously ill patients among the vaccinators.

Many people think that this is the arrival of God’s grace! Developed countries such as the United States and Britain have booked the products of these two companies in advance. China’s Fosun Company also signed a cooperation agreement with Pfizer and has completed the first phase of clinical trials. It is expected that the related Phase 2 will be launched in China soon.(Non-random)Clinical research to obtain the approval of China FDA.

Figure/A nurse and patient in California. In many parts of the United States, the pressure on the health system has been overwhelmed and is on the verge of collapse at any time.

Although American health insurance and the government will pay the cost of vaccination, another difficulty is that more than 37% people in the United States are not at ease with the vaccine and are not prepared to vaccinate immediately. In this regard, three former presidents of the United States, Bush, Clinton and Obama, said that they would vaccinate under the observation of the media at the first time as a platform for vaccine safety.

Because the vaccine is for normal people, it is not a "medicine", not to treat patients, but to prevent diseases. Meanwhile, for COVID-19 vaccine, the population to be vaccinated is billions of healthy people, including children.Therefore, its safety must be much stricter than that of "medicine".Therefore, if time is not pressing, all new vaccines should wait for a long time.(more than 2 years)The data will be finally approved. But in the face of a serious epidemic, this is irrational. The regulations that allow emergency use are designed for this situation.

At present, FDA requires that the last patient should be observed for at least 2 months after entering the Phase III clinical study to ensure that there are no serious acute side effects. Moreover, regulators must strictly control the use of these new vaccines from the beginning. The initial use of these vaccines is limited to those who need them most-doctors, nurses, other health care workers, and the elderly in nursing homes. Regulators also need to continue to closely monitor the side effects of vaccines already on the market.(so-called Phase IV Clinical Study). With the accumulation of data in the first two months of next year, the range of vaccinators will be further expanded.

The development of human society always strives for survival first, and then for improvement and perfection.

When the hopes of the whole world are pinned on the COVID-19 vaccine, the hardest work has just begun. We know that the best antiviral function of the vaccine will not be realized until two weeks after the second vaccination.In other words, for most people, December this year, January and February next year will be the darkest moments in the medical history of the United States since the Spanish influenza pandemic in World War I.

According to Dr. Fauci, director of the Institute of Infectious Diseases of the National Institutes of Health, it is estimated that by March next year, about 500,000 people in the United States will die in COVID-19, surpassing the number of deaths in World War II in the United States.(about 400,000). Regrettably, some people in the United States still refuse to wear masks and social isolation. Up to now, 37% people are skeptical about vaccines, and the epidemic prevention work has a long way to go!

Controversy over vaccines(Inoculation or non-inoculation, domestic or imported)The reason and background are very complicated, and it will not stop for a while. As a scientist and a doctor, I care most about yourself! Vaccinate, not only for others, but also for yourself!


This article comes from WeChat WeChat official account:CC weekly (id: cancer-weekly), Author: Zhang Yujiao (tenured professor of The University of Texas MD Anderson Cancer Center)

Regarding the pledge of 13.4 billion deposits, Evergrande took China Evergrande to court.

With regard to "the deposit of 13.4 billion yuan of Evergrande Property was pledged by relevant banks", the latest progress was made, and Evergrande Property put China Evergrande in the dock.

On November 28th, Evergrande Real Estate announced that about 13.4 billion yuan of deposit pledge of the Group (Evergrande Real Estate and its subsidiaries) was enforced by relevant banks, and jinbi property Co., Ltd., a wholly-owned subsidiary of the Company, had recourse against Shenzhen Qihang Metal Materials Co., Ltd., Guizhou Guangjuyuan Real Estate Development Co., Ltd., Evergrande Real Estate Group Guiyang Real Estate Co., Ltd., Evergrande Real Estate Group Co., Ltd. and China Evergrande Group (the responsible party) for about 2 billion yuan of deposit pledge guarantee enforced by banks in jinbi property.

According to the announcement, Evergrande Property requested the responsible party to repay more than 2 billion yuan, including the original amount of about 1.996 billion yuan and provisional interest of about 152 million yuan. On November 28th, Evergrande Property received a formal notice from the court to accept the case.

Evergrande Property stated in this announcement that according to the analysis of the board of directors and its legal counsel,The lawsuit will not have a significant adverse impact on its daily business operations, and the company will continue to make every effort to recover the relevant deposit pledge.Further announcements will be made in due course on any significant progress in the above litigation or any other actions taken.

The dispute between Evergrande Property and Evergrande was triggered by the huge pledge deposit disclosed in March 2022.

On March 22, 2022, Evergrande Property disclosed that during the audit of the 2021 financial report, the company found that about 13.4 billion yuan of deposits were pledged by third parties and were enforced by relevant banks.

The "13.4 billion yuan deposit pledge" incident has a great impact and a wide range of implications, and it is also one of the important factors that led to the suspension of the Evergrande Department for a long time. Therefore, Evergrande set up an independent investigation committee and appointed experts to investigate the pledge.

According to the independent investigation results of the previous "13.4 billion yuan deposit pledge" incident, during the period from December 28, 2020 to August 2, 2021, six subsidiaries of Evergrande Property (jinbi property, Jinbi Hengying, Jinbi Huafu, Evergrande Hengkang, Jinbi Shijia and Jinbi Hengkang) provided this pledge to a number of third-party companies (as the guaranteed parties) through eight domestic commercial banks in China.

The purpose of this pledge is to continue to use the special financing business to obtain funds for other operational and financial needs of the Group, including paying liabilities and/or payables due at different times in 2021.

It is reported that from September to December, 2021, due to the expiration of the pledge guarantee period, the conditions for the realization of the pledge right were triggered, and the total value of the deposit certificate pledge of the subsidiary company of Evergrande Property, which was enforced by the bank, was 13.4 billion yuan.

According to the previous announcement issued by Evergrande Property, the pledge is divided into three groups, the first group is 2 billion yuan, the second group is 2.7 billion yuan, and the third group is 8.7 billion yuan. What Evergrande Property recovered from China Evergrande this time was the first group of deposits.

The background and reason for the pledge is that in the middle to late December of 2020, based on the capital demand of Evergrande, the Group proposed to launch a special financing business. The specific scheme is to use the subsidiary company to pledge to provide guarantee for the third party to apply for financing from the bank, and the funds obtained from the third party financing will be invested in the Group to pay the liabilities and/or payables in February of 2021.

Further investigation shows that among the directors in the relevant period, Xu Jiayin, Xia Haijun and Pan Darong have access to and hold relevant documents, which may enable them to pay attention to the company’s capital situation. Xu Jiayin used to have documents that might draw his attention to potential financial problems, but he said that he did not review these documents because no one specifically reminded him of them. The consultant of the Independent Investigation Committee noticed that this was consistent with his previous statement that although he would receive many reports, he did not read them, because at the critical time, he was not in charge of the company’s finance and funds, but relied on the senior executives responsible for finance and funds to handle related matters.

The independent investigation also found that some documents related to the pledge guarantee arrangement were signed by Xu Jiayin, involving the cross-border transfer of funds from some domestic subsidiaries of the group to the company and the approval of the use of funds to redeem overseas bonds in advance. The internal approval document signed by Xu Jiayin did not clearly indicate that it was related to Evergrande Property, but only mentioned the internal funds of the Group.

The above funds come from the funds raised by the listing of Evergrande Property. According to the results of the supplementary independent investigation, after the proceeds from the initial public offering of Evergrande Property were remitted, because there was no special account for the proceeds at that time, the proceeds were confused with the self-owned funds of Evergrande Property, which were used for the daily operation of the company, resulting in the failure to find out in time that the relevant funds were used for the pledge guarantee arrangement.

Evergrande Property said that after learning of the pledge, it immediately carried out internal control review, personnel adjustment and other remedial measures, accepted the suggestion of the Independent Investigation Committee, implemented various remedial measures, and continued to carry out recovery work from third parties and Evergrande Group.

Many people in the industry believe that it is difficult for Evergrande Property to recover this sum because China Evergrande is in trouble.In August this year, Evergrande Property stated that it had not yet reached a repayment plan with China Evergrande. Meanwhile, the property management of Evergrande assessed the recoverability of this sum and made full provision for the 13.4 billion yuan receivable.

Compared with the other two listed companies of Evergrande, China Evergrande and Evergrande Automobile, Evergrande Property is one with relatively good fundamentals.

Evergrande mentioned in the newly disclosed resumption guidelines that the company has sufficient assets for business operation. In 2022, the total operating income was about 11.81 billion yuan, gross profit was about 2.72 billion yuan, and net profit was about 1.48 billion yuan.

According to the interim financial report for 2023 released by Evergrande Property, the revenue in the first half of the year was 6.145 billion yuan, an increase of 6.2% compared with 5.788 billion yuan in the same period of 2022, of which the revenue from non-related parties accounted for about 98.9%; The net profit was 790 million yuan and the net interest rate was about 12.9%.

During the reporting period, the contracted management area of Evergrande’s property was about 812 million square meters, and the managed area was about 509 million square meters. In the first half of the year, the contracted area was 15.14 million square meters, of which 93.3% came from third parties.

In terms of accounts receivable, the trade receivable of Evergrande Property during the reporting period was 3.244 billion yuan, an increase of 18.44% compared with 2.739 billion yuan on December 31, 2022; In addition, other receivables except trade receivables increased from about 460 million yuan on December 31, 2022 to about 544 million yuan in the reporting period.

In this regard, Evergrande Property also explained in the interim report that the increase in the company’s accounts receivable was mainly due to the increase in the total income of the group and business expansion, and the increase in the balance of deposits and advances on behalf of owners.

The mid-year report also pointed out that in 2023, the company seriously reflected on the nature of the property industry, no longer blindly pursued rapid scale expansion, bid farewell to extensive growth, and instead pursued high-quality, high-quality and profitable sustainable development.

(This article first appeared in Titanium Media APP, author | Wang Jian)

For more macro research on dry goods, please pay attention to WeChat official account, an international think tank of titanium media.

Perspective on the security risks behind "online celebrity Project" cooking tea around the stove.

  Xinhua News Agency, Shanghai, March 14th Topic: Perspective on the security risks behind the "online celebrity Project" cooking tea around the stove.

  Xinhua News Agency "Xinhua Viewpoint" reporters Dong Xue, Cheng Siqi, and Youzhi

  Three or five friends sat around the fire to make tea, and the tea was fragrant; Paired with freshly baked sweet potatoes, oranges and chestnuts, the atmosphere is full. However, with the popularity of cooking tea around the stove, many people "try early" at home, causing safety problems such as carbon monoxide poisoning.

  Fire experts suggest that it is not recommended to use charcoal fire to cook tea indoors. Insufficient combustion of charcoal will generate carbon monoxide, and excessive concentration will cause life-threatening. Even if it is fully burned, the oxygen content is declining, which is also harmful to health. In addition, it is necessary to guard against fire risks caused by open flames and high temperatures.

  Closed indoor measurement: it only takes 15 seconds for the carbon monoxide detector to give an alarm.

  A few days ago, a man in Shanghai reported to the police that two of his friends suddenly fell into a coma while eating. After the police arrived at the scene, they found that a charcoal stove for cooking tea was burning in the room, so they immediately took the charcoal stove to the rooftop and opened the window for ventilation. Fortunately, the three people were treated in time and were out of danger.

  Recently, cooking tea around the stove has become a popular item for tea room leisure and family gathering. It is recommended to punch in, share equipment and ingredients, take photos and videos … … There are more than 750,000 notes about cooking tea around the stove in Xiaohongshu, and the popular videos about experiencing cooking tea around the stove in Tik Tok have attracted more than one million praises. According to the data of Tianyancha, nearly 30 enterprises in the name of cooking tea around the stove have been established in China recently, and related trademarks have been registered by many parties.

  Cooking tea around the stove is a beautiful thing, but if it is done in a closed room, it will easily cause carbon monoxide poisoning. "Carbon monoxide is colorless and tasteless, and it is not easy to be detected. If the concentration exceeds 0.05%, it will cause harm to the human body." Chen Yuan, an engineer at the Fire Control Technology Division of the Fire Rescue Detachment in Huangpu District, said, "Mild carbon monoxide poisoning is characterized by severe headache, dizziness, weakness of limbs, nausea, vomiting, mild disturbance of consciousness and lethargy, and patients with coronary heart disease may have angina pectoris. If it is not treated in time, it will be life-threatening. "

  The experiment of cooking tea around the fire in Huangpu District, Shanghai shows that in a closed room of about 60 square meters, only 15 seconds after the firemen lit the charcoal fire, the carbon monoxide detector gave an alarm. At 1 minute and 50 seconds, the concentration of carbon monoxide has exceeded 0.01%.

  Firefighters are doing experiments to detect the concentration of carbon monoxide. Xinhua News Agency reporter Cheng Siqi photo

  Improper operation of cooking tea around the stove has caused many accidents and casualties. During the Spring Festival this year, a mother and son in Yangzhong, Jiangsu Province, used a cast iron charcoal stove to cook tea at home. Because of the cold weather, they closed the doors and windows and died of poisoning. In January this year, a woman in Weifang, Shandong Province was cooking tea around the stove at home. After 3 hours, she felt a little unconscious and accompanied by vomiting. She went to the hospital for examination and found that it was moderate carbon monoxide poisoning.

  Chen Yuan analyzed that compared with oxygen, carbon monoxide binds to hemoglobin in blood faster and dissociates more slowly. Carbon monoxide takes up a lot of hemoglobin, which will make the human body lose the ability to carry and transport oxygen, thus leading to poisoning. In addition, carbon combustion will consume oxygen and accumulate carbon dioxide; When the indoor oxygen content is as low as 10%, it may be life-threatening.

  Fire risk should not be underestimated.

  Due to the problems of open fire, continuous high temperature, uneven quality of ovens and unskilled operation, fire experts also highlighted the fire risk behind cooking tea around the stove.

  — — Produce open flames and high temperatures. "When it is lit, Mars splashes out, especially if you can’t fan the wind. The more fans there are, the more Mars there are. Fortunately, there is nothing easy to burn on the table, otherwise I am really worried about the fire. " Ms. Zhang, a citizen of Beijing, said.

  Gao Yan, supervisor of the comprehensive guidance section of the fire rescue detachment in Putuo District, Shanghai, explained: "On the one hand, the charcoal burning time is too long and the temperature is too high. If you accidentally knock over the stove, it may cause combustible materials to burn. On the other hand, it takes a long time for the charcoal fire to burn out. If you forget to put it out after cooking tea around the stove, it may also cause a fire. "

  — — The quality of the oven is uneven and the operation is unskilled. The reporter noticed that the tools for cooking tea around the stove are very simple: a charcoal fire oven made of cast iron or pottery, a mesh baking tray, a teapot and some charcoal. E-commerce, group buying and other platforms are sold, and the package price ranges from tens of yuan to one or two hundred yuan.

  "It only burned twice, and the chassis burned a hole." In a photo taken by a buyer, the hole in the bottom of the cast iron charcoal oven is clearly visible. A number of interviewees said that the oven they bought was not insulated: "The temperature on the outer surface of the oven was very high, and the first operation was unskilled, which burned the table."

  — — There is an overload of electricity. Some businesses began to use electricity instead of charcoal fire. In the Yijing Xiaoshe Tea Room in Putuo District, Shanghai, the electric oven used by merchants is similar in shape to a pottery oven. After being electrified, the resistance wire is red and hot, and the high temperature on the surface of the oven can be felt by touching it with your hands. "At first, we used charcoal to cook tea around the stove. Later, for safety reasons, we changed to electricity, and the customer’s acceptance was not bad." The person in charge of the store said.

  There are tea rooms that use electricity instead of charcoal. In the picture, the appliance for cooking tea around the stove is an electric stove. Xinhua News Agency reporter Cheng Siqi photo

  Gao Yan suggested that changing carbon to electricity can really avoid carbon monoxide poisoning and other problems, but the fire risk of using this electric furnace still exists. Most of these electric furnaces are high-power electric equipment, which is easy to cause pressure on the circuit. Especially, it is possible for multiple boxes in the teahouse to use multiple electric furnaces at the same time, so it is necessary to prevent fires caused by overload electricity.

  Tea should be cooked well and safely.

  In order to cook tea around the stove safely and comfortably, Chen Yuan suggested that we should start from all aspects and standardize the safe operation at every step.

  First of all, before cooking tea around the stove, you should buy utensils in regular shops and platforms, and you can’t find charcoal burning tools at will.

  Second, try to choose outdoor places with open ventilation such as terraces and rooftops. If it must be carried out indoors, it is necessary to keep the windows open and ventilated, and it is best to use smoke extraction facilities.

  Third, during the cooking process, reasonably adjust the spacing of items, stay away from combustible materials, and put heat insulation pads under the stove. At the same time, prevent children from approaching or touching charcoal burning equipment to prevent accidents such as burns. "Try to avoid baking things with high oil content, otherwise a large number of oil droplets will fall into the charcoal and the flame will soar." Chen Yuan added.

  Finally, the charcoal fire must be extinguished after the tea is cooked around the stove. It is best to take the stove outdoors and add water to cool it, or wait until the charcoal burns out and completely ashes.

  Ms. Ma, a citizen of Shanghai, suggested that the merchants who cook tea around the stove explain the precautions to customers in detail in advance. "Some merchants default that customers understand the procedures for cooking tea around the stove, and do not give necessary safety reminders. Customers can operate whatever they want, which has certain security risks."

  Gao Yan suggested that customers should first understand the safety exits and evacuation passages when entering the tea room, and check the location of fire extinguishers such as fire hydrants. It is suggested that businesses should add fire extinguishing appliances. If electric furnaces are used, businesses should regularly check whether the circuits are aging and whether the electric furnaces are normal, and avoid connecting multiple high-power electrical equipment to the same socket at the same time.

Notice on printing and distributing the implementation plan for standardized training of residents and recruitment of assistant general practitioners in Anhui Province in 2020

Now "The Implementation Plan for the Recruitment of Standardized Resident Training and Assistant General Practitioner Training in Anhui Province in 2020 is issued to you. Please do a good job in the recruitment and implementation according to the actual situation and provide necessary safeguard measures for the training. If there are any problems in the implementation process, please contact the Science and Education Department of our Committee and the Management Center of Provincial Housing and Training Affairs at telephone number:

Shengzhupei affairs management center           0551-62284812     

Provincial Health Commission Science and Education Division           0551-62998587

Technical support of housing and training information management system  0551-62530721

Anhui province health health Committee

June 29, 2020

(Information disclosure form: voluntary disclosure)

 

 

 

Standardized training of residents in Anhui Province in 2020 and

Implementation plan for training and recruiting assistant general practitioners

 

In order to implement the "Implementation Opinions on Establishing a Standardized Training System for Residents in Anhui Province"[2015] No.183), strengthen the management of standardized training for residents/training for assistant general practitioners, ensure the unified, scientific, standardized and orderly training and recruitment, and ensure the quality of training and recruitment. This plan is formulated according to the relevant policy requirements of the state and our province.

First, the recruitment plan

In 2020, the standardized training program for residents in our province enrolled 3386 people, including 3066 people in western medicine and 320 people in Chinese medicine. The training program for assistant general practitioners enrolled 280 people, including 200 in clinical category and 80 in traditional Chinese medicine category.

See Annex 1 for the enrollment plan of standardized resident training/assistant general practitioner training in Anhui Province in 2020, Annex 2 for the enrollment plan of order-oriented medical student training, and Annex 3 for the assignment table of the specialties in short supply in cities and counties directly under the provincial government.

Second, the object of recruitment

Recruiting objects are divided into two types: training objects appointed by the unit (hereinafter referred to as "unit people") and socialized personnel (hereinafter referred to as "social people").

(1)Recruiting target of standardized training for residents

1. Basic conditions (one of the following conditions is enough)

(1) Graduates with bachelor’s degree or above who have been or intend to be engaged in clinical medical work in full-time colleges and universities majoring in medicine (referring to clinical medicine, stomatology, traditional Chinese medicine and integrated traditional Chinese and western medicine, the same below).

(2) Persons who have been engaged in clinical medical work and obtained the qualification of medical practitioners and need to be trained.

2. Application conditions and requirements

(1) applicants must be qualified as medical practitioners or registered as medical practitioners.Case, and has not obtained the certificate of standardized training for residents of junior or no title personnel.

(2) inPostgraduates with professional degrees and scientific degrees are not included in the scope of this recruitment.

(3) The professional categories (clinical, oral and traditional Chinese medicine) applied for should be consistent with the professional categories studied.

(4) The employer must obtain the consent of the appointing unit before applying for the exam, and the information about the training specialty, training base hospital and so on must be consistent with the letter of introduction stamped by the employer. Professional (base) volunteers are limited to 1 and base (hospital) volunteers are limited to 3.

(5) Social people fill in their volunteers according to their own reality, and the number of professional volunteers (bases) is limited to 3, and the number of base volunteers (hospitals) is limited to 3.

(6) In principle, the training objects appointed by primary medical and health institutions are limited to general practice, and the training objects appointed by central township hospitals can also apply for internal medicine.

(7) The 2020 rural order-oriented free medical undergraduate graduates must apply for the standardized training of general practice residents in a unified way.

(B) Assistant General Practitioner Training Recruiters

1. Basic conditions

Full-time graduates of medical majors (referring to clinical medicine and traditional Chinese medicine, the same below) who have been or intend to engage in clinical medical work.

2. Application conditions and requirements

(1)Applicants must beJunior or non-professional personnel.

(2)Enter oneself for an examination professional category (clinical, Chinese medicine) should be consistent with the professional category.

(3) The employer must obtain the consent of the appointing unit before applying for the exam, and a letter of introduction issued by the employer for agreeing to apply for the exam is required for qualification examination.

(4)twentytwentyThe rural order-oriented free medical college graduates must be in units.Enter oneself for an examination in person modeAttend assistant general practitioner training.

Third, the recruitment process

The recruitment work is carried out in accordance with the procedures of online registration, qualification examination, examination admission and publicity registration.

(1) Examination registration

This exam adopts online registration, and the applicants log on to the information management system platform of resident training in Anhui Province (http://220.178.116.78:9889/)To register, the registration start and end time is8: 00 on July 6th, 2020-17:30 on July 10th.

(2) Qualification examination

From July 6 to July 11, 2020, the applicants went to the first volunteer base hospital for on-site qualification examination.

From July 13 to July 16, 2020, the Provincial Health and Wellness Committee organized relevant personnel to review the qualifications of those who passed the preliminary qualification examination of each base hospital, and determined those who took the examination.

At the time of on-site qualification examination, applicants are required to provide the following materials:

1. A printed and signed Registration Form for Admission Examination for Standardized Training of Residents/Training of Assistant General Practitioners in Anhui Province in 2020 (printed directly from the platform after registration);

2. One original and one copy of the ID card;

3. One original and one copy of the certificate of bachelor degree or above, or one original and one copy of the qualification certificate of medical practitioner.

4. Letter of introduction from the unit (provided by the unit).

(3) Print the admission ticket

From 8: 00 on July 20, 2020 to 17:30 on July 24, 2020, qualified personnel logged on the platform of Anhui resident training information management system to print the admission ticket.

(4) Examination admission

The examination method is a comprehensive written medical examination, with unified proposition and marking in the whole province. The examination categories are divided into five categories: clinical medicine, stomatology, traditional Chinese medicine, clinical assistant general practice and traditional Chinese medicine assistant general practice. Examination time:From 9: 00 am to 11: 30 am on July 25, 2020, see the admission ticket for the examination place.

followThe principle of "openness, fairness, merit-based admission and two-way selection", according to the examination results of candidates, according to the voluntary priority to determine the admission training targets. If the base hospital or the corresponding major fails to complete the enrollment plan, it will be transferred from the staff who obey the transfer; Accommodation and training transfer admission gives priority to meeting the urgent and scarce professional needs of general practice, pediatrics, psychiatry, obstetrics and gynecology.

(five) publicity report

After the recruitment, the Provincial Health and Wellness Committee will publicize the results of the recruitment to the public in a timely manner.

After receiving the official list of admission personnel, the training base shall inform the trainees of the registration time and related requirements in time. The training time starts from the date of training, and serves as the basis for enjoying relevant financial subsidies. The training object appointed by the unit shall be signed by the appointing unit, the training base and the training object (Annex4 or Annex 6), the trainees must return to their original units after the training, and the training base shall not retain the trainees appointed by the units; The training base signs a training agreement (Annex 5 or Annex 7) with the trainees who are recruited for the society, and the files are placed in the talent exchange center designated by the training base. After the training, the trainees choose their own jobs. Those who can’t report on time must have justified reasons and relevant certificates, and ask for leave from the training base hospital, and postpone the corresponding training time after reporting; Those who fail to report for a week without reason will be disqualified from the training and will be deemed to have withdrawn from the training on their own.

Fourth, requirements

(a) forImplement the State Council’s deployment of novel coronavirus epidemic prevention and control and the requirements of the provincial party Committee and the provincial government to ensure thatDuring the examination, the life safety and physical health of the majority of candidates and examination staff are ensured, and the examination and assessment work is carried out smoothly. All localities and units should strictly follow the implementation of the COVID-19 epidemic prevention and control work plan during the standardized training and examination of residents (see Annex8)。

(two) municipalities and counties directly under the jurisdiction of the Health and Health Committee should strengthen leadership and raise awareness, and do a good job in the publicity and guidance of standardized training policies for residents; Supervise the medical institutions within the jurisdiction to actively mobilize and send qualified personnel to sign up for the training, and ensure that in accordance with the relevant provisions of the state and our province’s health science and education secret [[2015] No.183 requires the implementation of relevant treatment for trainees. It is necessary to actively select personnel from medical institutions at all levels to participate in the standardized training of general practitioners/assistant general practitioners, focus on the construction of general practitioners, and at the same time take into account the selection of training in pediatrics, obstetrics and gynecology, etc.Ensure the completion of the recruitment task of the shortage of majors.Formulate a tilt policySupport personnel who meet the training requirements in underdeveloped areas and poverty-stricken counties such as Dabie Mountain Revolutionary Old District and northern Anhui to participate in the training. Strengthen the pairWork supervisor of subordinate base,Do a good job in the implementation of recruitment and training.

(2) Medical institutions at all levels should mobilize qualified personnel to actively register, and the appointed units should determine the future professional positions of the dispatched personnel before registering. The letter of introduction should specify the corresponding training majors, and individuals and units may not apply for adjustment of training majors unless due to force majeure. After the training, the appointed unit will carry out its post in strict accordance with the training specialty determined by the letter of introduction. Establish and improve the relevant systems, strengthen the management of the training objects sent by the unit, and do a good job of communication and communication during training; Formulate corresponding incentive policies and safeguard measures, timely pay or distribute the post salary, salary scale salary, social insurance, housing accumulation fund and corresponding welfare that the dispatched unit should bear according to the regulations, and ensure the implementation of the treatment stipulated in the policy during the training period.

(III) Each training base shall, in accordance with the requirements, formulate its own recruitment brochure, publicize the characteristics, characteristics and advantages of the base, clarify the base treatment of trainees, formulate preferential policies for applicants with major shortage and social people, improve the enrollment rate and admission rate of major shortage and the proportion of students with social people, and strive to complete various recruitment plans. Carefully review the registration qualifications, make early preparations for new students to enter the base, and ensure that the registration and pre-job training are successfully completed within the prescribed time limit; Sign the training agreement in time to ensure that all kinds of subsidies are paid in place during the training of the trainees. The completion of the recruitment plan of each training base, especially the completion of the tasks of the shortage of majors such as general practice, will serve as an important basis for the dynamic management of training bases, financial subsidies, striving for Excellence and the allocation of enrollment places in the next year.

(four) improve the integrity system of standardized training for residents, and will be informed of dishonest behavior. Once verified, the applicants who practise fraud in the training and recruitment work will be disqualified from registration and training, andWithin 3 years (2 years for assistant general practitioners), you may not enroll in standardized training for residents or enter standardized training for residents in other forms (such as applying for professional degree graduate students, etc.); For the admitted trainees (subject to the public list), if they fail to report for duty or quit the training after reporting for duty due to personal and non-force majeure reasons, they shall not sign up for standardized training for residents within 3 years (2 years for assistant general practitioners) or enter the standardized training for residents in other forms (such as applying for professional degree graduate students). If the unit person withdraws from the training due to the reasons of the unit, it will be included in the target assessment of the city or unit, and will be linked to the performance appraisal of public hospitals. For the training base that violates discipline and discipline in the recruitment and training work, informed criticism will be given until its base qualification is cancelled, depending on the seriousness of the case.

 

Attachment:1. Standardized training for residents in Anhui Province in 2020/Assistant General Practitioner

Training enrollment schedule

2.2020 order-oriented medical student training enrollment schedule

3.2020 Assignment Table for Specialties in Shortage in Cities

4. Standardized Training Agreement for Residents in Anhui Province (unit)

5. Standardized training agreement for residents in Anhui Province (social person)

6. Anhui Assistant General Practitioner Training Agreement (unit)

7. Anhui Assistant General Practitioner Training Agreement (social person)

8. COVID-19 epidemic situation during standardized training and examination for residents.Prevention and control work plan

Attachment 1-1: Allocation Table of Anhui Resident Standardized Training Enrollment Plan in 2020. xlsx
Attachment 1-2: Anhui Assistant General Practitioner Training Enrollment Schedule in 2020. xls
Attachment 2: 2020 Order-Oriented Student Training Enrollment Schedule. xlsx
Attachment 3: Assignment Table for Major Selection in Shortage in Cities in 2020. xlsx
Attachment 4: Standardized Training Agreement for Residents in Anhui Province (unit). doc
Attachment 5: Standardized Training Agreement for Residents in Anhui Province (social person). doc
Attachment 6: Anhui Assistant General Practitioner Training Agreement (unit). doc
Attachment 7: Anhui Assistant General Practitioner Training Agreement (social person). doc
Attachment 8: Work Plan for Epidemic Prevention and Control in COVID-19 during the Standardized Training and Examination for Residents. doc

Multinational pharmaceutical companies absorb high-ranking children: Feng Yuxiang’s grandson Ren Huirui’s top management

Multinational pharmaceutical companies absorb high-ranking children: Feng Yuxiang's grandson Ren Huirui's top management

  In the crazy process of multinational pharmaceutical companies in China, grey means frequently appear. The GlaxoSmithKline case is just the tip of the iceberg. What are the criteria for multinational pharmaceutical companies to choose executives in China? What kind of deep background do they have?

  After four senior executives of GlaxoSmithKline were detained, AstraZeneca, Sanofi, Lilly and other giants were also investigated by relevant departments, and the bribery scandal of multinational pharmaceutical giants intensified.

  Multinational pharmaceutical companies have been operating in China for 30 years. Facing the huge market in China, the development and expansion of multinational pharmaceutical companies in China is more like a long-planned war. From the initial joint venture, to merger and acquisition, sole proprietorship, setting up factories and R&D centers in China, even the executives in China have changed from foreigners to local elites.

  From tourism to immigration, from interviews to papers, the "grey marketing techniques" of pharmaceutical companies have also exposed the tip of the iceberg.

  How do multinational pharmaceutical companies operate in China, and what are the arrangements for the establishment of various functional departments? How can multinational pharmaceutical companies penetrate into China step by step by relying on their strong economic strength and powerful government lobbying ability? What is the background of executives of multinational pharmaceutical companies?

  Department secrets

  The outbreak of GSK’s China Wo case presented a roadmap for a foreign company to promote drugs by illegal means in China. Zhao Hongyan, director of the legal department, liang hong, vice president and general manager of enterprise operation, Huang Hong, general manager of business development enterprise operation, and Zhang Guowei, president and director of human resources department, who are known as "GSK China Troika", were investigated by the public security department. Why did GSK executives in China collectively fall?

  The reporter found that there is a very clear division of labor among mainstream European and American pharmaceutical foreign companies. The medical management of multinational pharmaceutical companies in China has been covered with political color.

  A deputy general manager of a domestic pharmaceutical company told reporters, "Every multinational pharmaceutical company has different ways to play. The national market layout of multinational pharmaceutical companies in China is basically where the government relations built by the enterprises themselves extend. Considering the operation and security of multinational pharmaceutical companies in China, one of the main tasks of government relations management is short-term arrangement, medium-term plan and long-term plan, and there is a special annual budget for the expansion and maintenance of government relations. "

  "Simply relying on market operation is not enough to maintain the production and development of enterprises. For example, the bidding management of provinces, the selection of essential drugs, the addition of medical insurance catalogues, and the new GMP standards will all be controlled and influenced by relevant national policies. Therefore, on the first day of investment in China, multinational pharmaceutical companies in Europe and the United States regard influencing government-related decision-making departments as their most important task. " A staff member of a medical association told reporters.

  Pharmaceutical enterprises build their own government relations network nationwide, on the one hand, relying on the government relations department of the company, on the other hand, giving full play to the personal connections and business capabilities of resident marketers, and on the other hand, relying on the commercial customers of pharmaceutical enterprises.

  An industry insider who did not want to be named said, "Multinational pharmaceutical companies are even more aware of the layout of approval power before and after the reform than government officials, and their familiarity with policies, laws and regulations is much higher than that of domestic pharmaceutical companies."

  There are 11 departments in China headquarters of GSK. The four departments involved in this case are Legal Affairs, Human Resources, Business Development and Enterprise Operation. What is the department setup and division of responsibilities of multinational pharmaceutical companies in China?

  The Ministry of Government Affairs is mainly responsible for developing and carrying out related work with National Medical Products Administration, the National Development and Reform Commission, the Price Bureau, the industrial and commercial departments, the Ministry of Justice and other government functional departments, and establishing and maintaining good communication and contact with relevant units and departments. For example, be responsible for the company’s product declaration and selection in the national or local basic medical insurance drug list, and ensure that the company’s products are selected in the trade name list or synonym library in relevant regions; Responsible for the bidding and winning of the company’s products in relevant regions of the country, improve market access, and ensure that the company’s products have good channel environment and policy environment support.

  The Ministry of Public Affairs is mainly responsible for the work in the media and public propaganda. Publicize the public through some influential media or propaganda tools, such as newspapers, magazines, radio and television, and shape public opinion, thus affecting the decision-making of government departments or legislatures. In addition, carry out social welfare projects advocated by the government to shape the positive image of enterprises. Some common problems are provided to the legislature or decision-making body as experts and scholars or as alliance groups through industry associations, industry media, academic groups, etc.

  Medical registration department, mainly dealing with new drugs on the market and National Medical Products Administration. Get more guidance and help from the national level, improve the efficiency of pharmaceutical companies in research and development, registration and approval of new drugs, and obtain policy support for existing products.

  Business development department, mainly dealing with local pharmaceutical wholesale companies and price departments. Provide accurate and continuous information, trends and related policy analysis for internal departments of the company; Drafting opinions and supporting materials to provide reference and necessary support for other internal departments to negotiate with the official; Ensure the stability of the price system of pharmaceutical products.

  The legal department is mainly responsible for dealing with the legal troubles that the company may face. Based on the long-term research on the policy and market of pharmaceutical industry, it provides policy judgments for pharmaceutical companies in their business decisions. Because multinational pharmaceutical companies are familiar with the laws of China, they directly contact legislators or government officials with decision-making power through formal meetings or other means, such as cooperating with the government to present the company’s position and views on behalf of the company, provide relevant information and share practical experience, so as to influence the decision-making of the government or legislative departments.

Insist on "Three Possessments": Give Full Play to the Special Functions of Newspaper Layout —— An Analysis of the Innovation of Military Newspaper Layout from the Winning and Selected Works of China N

Absrtact: Layout is the "face" of a newspaper, which plays an irreplaceable role in content dissemination. Focusing on giving full play to the special functions of military newspaper layout in the all-media era, this paper, based on the practice of news arrangement and the dissemination of selected works of China News Prize in recent years, explores the methods and paths of military newspaper layout innovation from three aspects: creating "visual storm", expanding multi-form information and highlighting media personality characteristics.

Keywords: China Prize for Journalism; News arrangement; Layout innovation; Military newspaper

The layout is the "face" of the newspaper, the visual presentation of the content, with special functions such as reading guidance, guidance, signs, etc. It is the exhibition place of newspaper ideas and plays an irreplaceable role in content dissemination. For military newspapers, it is their duty and mission to innovate the way of expression and communication based on content construction, carefully prepare the layout and hold the position of public opinion. Innovation is the first driving force to lead development, and innovation is the spiritual characteristic of the supreme leader’s cultural thought. When inspecting the People’s Liberation Army newspaper, President Xi clearly pointed out that content innovation, form innovation and means innovation are all important for news media, but content innovation is fundamental.

In the all-media era, content innovation needs the service guarantee of formal innovation. Focusing on giving full play to the special functions of military newspaper layout in the all-media era, this paper, based on the practice of news arrangement and the dissemination of selected works of China News Prize in recent years, explores the methods and paths of military newspaper layout innovation from three aspects: creating "visual storm", expanding multi-form information and highlighting media personality characteristics.

First, powerful: create a "visual storm" to attract more attention.

A good news layout is the unity of politics, news, ideology and artistry.

(A) highlight the weight, highlighting the political nature

?Turn it into a sharp ideological weapon and exert great power.

(B) outstanding attitude, reflecting the orientation

On February 2, 2016, the first edition of the People’s Liberation Army Daily won the second prize of the 27th China News Award. This edition focuses on the establishment of a war zone, an important event of national defense and military reform, and records this important historical moment with strong layout language and pictures. The layout highlights the key points, strengthens the transmission of important information and the visual impact of the layout, and highlights the style of big newspapers. Coincidentally, the August 5, 2022 edition of the People’s Liberation Army Daily, because of its clear stand, highlighted the weight and strength of the news and caused strong repercussions inside and outside the military. At that time, Pelosi, then Speaker of the United States Congress, insisted on visiting Taiwan, China despite China’s obstruction, and our army successfully held a joint combat training in the sea and airspace around Taiwan Island. The People’s Liberation Army Daily reported on the training in a run-through layout. The layout of the layout is concise, and the core facts are highlighted, which fully shows that our army is fully determined and capable of maintaining the motherland’s reunification and defending national sovereignty and territorial integrity. Practice shows that layout language is the natural expression of media’s position, viewpoint, emotion and aesthetic vision. As the mouthpiece of the Party, in the face of hot topics and sensitive issues, the mainstream media of the army should focus on making the layout an effective increment of content combat effectiveness, dare to speak out, speak out in time and be good at speaking out; It is necessary to make the news that should be done bigger and bigger, promote the supply of high-quality content, and ensure that the layout is coordinated in one go; Let the layout language have enough impact, clarify the facts and guide public opinion.

(3) Highlight emotions and increase appeal.

On July 31st, 2017, Edition A6 of Jinan Daily won the third prize of the 28th China News Award for newspaper layout. It stands out from its unique perspective in the competition of the same topic layout reflecting the 90th anniversary military parade. This page makes a fuss about the change of the detail that "the angle of military parade salute is raised from the original 15 degrees to 30 degrees", and the headline "It’s not just pride to hold your head up 30 degrees" has a strong emotional color; Carefully selected banner photos showing the heroic spirit of the two soldiers make the finishing point, which echoes and sets off the title. This layout not only brings visual shock to the audience, but also fully shows the heroic feelings of the Chinese nation standing tall among the nations of the world, which arouses empathy among the audience. It can be seen that the layout has language, attitude and emotion. Newspaper layout is a highly political business and political work. On the one hand, the mainstream media of the army should keep up with the changes of the world, the times and the history, establish a global vision, lead public opinion and guide the work; On the other hand, it is necessary to adapt to the new aesthetic changes of the audience in the all-media era, and make good use of layout language such as words, lines and colors to convey layout information and emotions more accurately and effectively, so as to enhance the reading experience of the audience.

Second, useful: multi-form information expansion, so that content presentation rushed out of the "first scene."

In the era of all-media, for newspapers, we should not only insist on the content as king, but also expand the form and service to make the layout "informative", "useful" and "powerful".

(A diagram, visual expression to achieve easy-to-read and interesting reading.

In the era of all-media, readers’ reading methods tend to be fast, fragmented and visual. Pictures and illustrations have become the most important and dynamic elements in newspaper layout because they are more intuitive and impactful than words in information transmission. In recent years, many of the winning pages of the China Prize for Journalism have enhanced their expressive power by adding data, charts and other elements. For example, the award-winning page of the 33rd China Prize for Journalism and the 5-8 edition of Jiangxi Daily on October 27th, 2022 are special commemorative pages to commemorate the 95th anniversary of the founding of Jinggangshan Revolutionary Base. With the help of the large-scale sculpture of "Jinggang Red Flag", the layout highlights the visual effect, and skillfully strings together important nodes such as "Wenjia City’s decision-making", "Sanwan adaptation" and "getting rid of poverty" in the form of a timeline, so that readers can visually feel the past struggle, current self-confidence and future expectations. Practice has proved that in the all-media era, a picture is worth a thousand words, and the mainstream media of the military should be good at using pictures to speak on the layout, so as to meet the aesthetic requirements of the audience in the era of reading pictures and make the news more readable and enjoyable; We should be good at arranging the relevant data in the news visually by means of charts, so that the boring and difficult data can be seen at a glance and arouse readers’ interest in reading; It is necessary to make it clear that the chart not only has the function of beautifying and activating the layout, but also is an independent and effective form of news reporting, strengthen the awareness of secondary processing, and help the transmission of its deep value through integrated refining and innovative presentation.

(2) Continuous version, carrying more content to create more space.

Of the six pages won in the 33rd China Prize for Journalism, five are consecutive pages. According to the data, in the past five years, 32 pages of the China Prize for Journalism have won awards, of which the single edition accounts for less than 25%. Continuous edition (all-page edition and cross-page edition) has become an important choice for newspapers to improve their communication power and influence. Take the award-winning page of the 32nd China Prize for Journalism and the 10-11 edition of the People’s Liberation Army Daily on July 1, 2021 as an example. This edition presents several classic moments of the People’s Army in the century since the founding of the Party in hand-painted form, with a clear theme and lofty ideas, which extends the sense of historical depth and makes readers feel refreshed. It can be seen that compared with ordinary single edition, continuous edition breaks the convention, makes the vision more impactful, can carry more content, and can better reflect the editing concept, thus producing a strong effect, so it has become the best choice for many newspapers. Some experts believe that this is also a useful exploration for newspapers to take the high-quality route and improve the quality and efficiency of communication in the all-media era. This enlightens us that in the all-media era, military newspapers should not only face the "fast" challenge brought by new media, but also give full play to their own strengths and work hard on the word "deep". We should focus on major themes, in-depth reports, elaborate designs around grand narratives; Change from "information paper" to "attitude paper"; Change from "design paper" to "collection paper".

(C) media integration, so that the layout "move up" and "live up"

In the all-media era, the layout language is more diverse. It is also an effective way to attract and retain the audience’s attention by making the layout "move" and "live" through the linkage of newspapers and networks. For example, in the winning pages of the 30th China Prize for Journalism and the 6-7 edition of Science and Technology Daily on October 1, 2019, when reporting the scientific and technological achievements made in the 70 years since the founding of New China, a QR code was added to the pages, and after scanning, the video of "70 years condensed into 24 hours" distributed synchronously by the newspaper can be watched. This innovation enriches the connotation of the layout and embodies the idea of media integration. For another example, the Liberation Army Daily, published on August 5, 2022, embeds the two-dimensional code of the video of the training site in the layout, which makes the news information richer and more comprehensive and meets the needs of the audience. It can be seen that in the all-media era, it is far from enough for newspapers to hold their ground in the flood of information. It is also necessary to expand information through media integration, broaden their horizons to below the appearance of news facts and outside the scene, and explore and explore more vital and inspiring three-dimensional pages.

Third, interesting: highlight the characteristics of media personality and enhance user stickiness.

Layout is an important part of the newspaper’s personality and style, which always plays the role of influencing readers and guiding public opinion.

(A) minor issues, tell a living story with details.

The second prize of the news layout of the 31st China News Award and the T7 edition of Xinhua Daily on April 14th, 2020, Thanks to You, the mountains and rivers are safe-paying tribute to the "epidemic" hero of Jiangsu’s aid to Hubei War, still seem to be a layout with special communication value. At that time, in order to welcome the triumph of the last batch of medical workers from Jiangsu who assisted Hubei, Xinhua Daily specially planned to launch a special tribute issue. As the cover of the special issue, this edition is carefully designed to outline the image of a well-armed medical worker with the names of 2,813 medical workers from Jiangsu who aid Hubei. Each name is regarded as a "point" in the picture, and they are connected in series by a "curve", and finally they converge into a meaningful "face" image. This treatment is meaningful: the success of the "epidemic" depends on specific people, and each person has a different story, thus achieving good communication results. Storytelling is the most effective communication. On the one hand, the mainstream media of the military should insist that content is king and continuously enhance their ability to provide content; On the other hand, we should pursue the harmony between content and form, strive to achieve the unity of form and spirit, and tell vivid stories with details; In particular, we should pay attention to digging points, cutting hot spots, falling points skillfully and tearing points, so that positive energy can generate large flow and good sound can become the strongest sound.

(2) Make the past serve the present, and the national wind ignites the new wind.

The prize-winning page of the 31st China Prize for Journalism and the 6-7 edition of Zhejiang Daily on November 23rd, 2020 were published at the opening of the "Light of the Internet" Expo in 2020. This edition takes the traditional "window" in China as the theme, and combines the unique "window lattice" element of Wuzhen water town with the new mission and new requirements of "important window" in Zhejiang. Through the image of "window" on the page, we can see the street view of Wuzhen and the Light Expo of the Internet, which makes the page have a sense of historical depth of blending ancient and modern, attracting people’s attention. After two years, on November 1st, 2022, the 6-7 edition of the newspaper won the 33rd China Prize for Journalism again with its strong national style and ingenious ideas. On this page, which shows the arduous course and great pioneering work of China’s space dream, the editor skillfully connects Su Shi’s words and images of "Palace Que in the Sky" with China Space Station across time and space, combining ancient and modern, and combining dreams with reality. Especially in the lower left corner of the layout, Su Shi is wearing VR glasses, looking up at the starry sky and singing "When did the bright moon ask the sky about the wine? I wonder what year it is in the palace palace tonight". The unique layout narrative method has injected poetic romance with Chinese style into serious scientific and technological topics, which is unique in many layouts with the same theme and has gained excellent communication effect. This enlightens us that in the all-media era, news content transmission is no longer the only pursuit of newspapers. It is necessary to comprehensively use richer editing methods in reporting, integrating national culture, aesthetic concepts and the value of the times, so that the audience’s reading can be changed from simple information acceptance to reading enjoyment based on understanding.

(C) associated with their own, related to the crowd.

In the all-media era, information is overloaded and attention becomes a scarce resource. Faced with a large amount of information, people will subconsciously pay attention to what is related to them, which is more familiar or interesting. Newspaper layout not only needs to carry forward the main theme and spread positive energy in a way that the audience likes and hears, but also faces the problem of connecting the content and expression form with the antenna and connecting them with the audience’s interests. The exploration of the winning pages of the 32nd China Prize for Journalism and the 2nd edition of People’s Daily on July 19th, 2021 is quite instructive. This edition focuses on the major theme of "achieving the goal of the first century-building a well-off society in an all-round way in China". In the way of presentation, it vividly shows the changes with 16 groups of data that best reflect the people’s sense of gain, happiness and security, and has both visual impact and ideological persuasion, making the boring and difficult data clear at a glance, narrowing the distance with the audience and achieving good communication effects. It can be seen that in the all-media era, the mainstream media of the military should work hard to show their own characteristics and improve the recognition and dissemination of newspaper pages. It is necessary to bring about a new release of narrative energy through the new development of layout means; It is necessary to enrich the new expressive force of two-dimensional space style and enhance the user’s stickiness; It is necessary to build news pages into witnesses of history and make newspapers readable, hidden and enjoyable.

(Author: People’s Liberation Army Newspaper)

Editor in charge: Zhang Heyun

Guangxi Finance Department standardizes the supervision and management of agricultural financing guarantee funds to further improve the efficiency of fund use.

  In order to further standardize the supervision and management of agricultural financing guarantee funds in Guangxi, promote the healthy and sustainable development of agricultural burden system in Guangxi, and improve the efficiency in the use of funds, recently, the Department of Finance of the Autonomous Region and the Department of Agriculture and Rural Affairs of the Autonomous Region issued the Measures for the Management of Business Reward Funds of Guangxi Agricultural Credit Financing Guarantee System (hereinafter referred to as the "Administrative Measures"). The "Administrative Measures" consists of six chapters, which mainly defines the scope of supplementary awards, supplementary awards standards, application and disbursement, system construction, budget performance management and supervision and inspection.

  First, clear the scope of financial support for agricultural compensation awards

  According to the spirit of the documents such as the Notice on the Measures for the Administration of Agriculture-related Transfer Payment Funds, the Notice on Further Improving the National Agricultural Credit Guarantee Work and the Notice on Further Improving the Agricultural Credit Guarantee Work to Help Rural Revitalization, combined with the actual situation of agricultural credit guarantee work in our region, the Finance Department of the Autonomous Region strongly supports the construction of agricultural credit guarantee system in Guangxi. Raise funds to give a supplementary award to Guangxi Agricultural Credit Financing Guarantee Co., Ltd. (hereinafter referred to as Guangxi Agricultural Bank Company) for its policy-oriented agricultural bank business that meets the requirements of "double control", focusing on supporting agricultural production (including agriculture, forestry, animal husbandry and fishery production and farmland construction) and industrial integration projects directly related to agricultural production, highlighting the production support for important agricultural products such as grain and pigs. Focus on supporting agriculture with small scale and low fees. The guarantee scale is limited to a single household’s guaranteed balance of no more than 10 million yuan, the guarantee rate charged to the loan subject of policy-based agricultural undertaking business is no more than 0.8%, and the comprehensive guarantee rate after financial subsidy (the sum of the loan subject and financial subsidy) is no more than 3%. Adhere to the service tenet of strengthening agriculture and benefiting farmers, firmly grasp the positioning of policy-based guarantee, and scientifically and reasonably determine the preferential guarantee rate.

  Two, standardize the use of funds application process

  In order to improve the standardization, accuracy and effectiveness of the application for supplementary awards, the Administrative Measures clearly require Guangxi Agricultural Support Company to submit an application for supplementary awards for agricultural support in the previous year to the Finance Department of the autonomous region and other departments according to the completion of the policy guarantee business in the previous year before the end of January each year. The Department of Finance of the Autonomous Region shall summarize and preliminarily examine the application funds, and submit them to the steering committee of agricultural credit financing guarantee in the whole region for deliberation, and allocate and use the supplementary award funds for the guarantee business issued by the central government in accordance with the relevant provisions of the centralized treasury payment system, constantly standardize the procedures for fund application and use, improve the efficiency in the use of funds, promote financial integration in the whole region, and help realize high-quality and efficient agriculture, livable and suitable rural areas, and rich farmers.

  Third, improve the construction of agricultural credit guarantee system

  The Department of Finance of the Autonomous Region encourages Guangxi Nongdan Company to carry out business cooperation with the pilot institutions of agricultural credit guarantee in cities and counties, and includes the cooperative business that meets the conditions of supplementary award policy into the scope of support of supplementary award policy, establishes and improves the agricultural credit guarantee system led by Guangxi Nongdan Company and supported by the agricultural institutions in cities and counties, constantly improves the construction of agricultural credit guarantee system in the whole region, promotes the coordinated development of all institutions of agricultural credit guarantee system, promotes farmers’ income and wealth, and injects "flowing water from the source" into the implementation of rural revitalization strategy.

  Fourth, strengthen performance management and supervision and inspection

  The Department of Finance of the Autonomous Region, together with the Department of Agriculture and Rural Affairs of the Autonomous Region and other departments, will further strengthen the whole process budget performance management of supplementary award funds for guarantee business, strictly evaluate the performance of supplementary award funds, effectively use and manage supplementary award funds, and continuously improve the scientific, refined and professional management level of fund budget performance. Strengthen the supervision and inspection of the audit and supervision of the use of supplementary award funds for guarantee business, prevent financial risks, improve the efficiency of the use of supplementary award funds for guarantee business to benefit farmers and enterprises, give full play to the leverage of financial funds to support agriculture, incite financial living water to promote agricultural development in Guangxi, and help Guangxi’s agricultural industry upgrade.