Measures of China National Intellectual Property Administration Municipality on Marking Patent Identification

the first In order to standardize the marking methods of patent marks and maintain the normal market economic order, these Measures are formulated in accordance with the relevant provisions of the Patent Law of People’s Republic of China (PRC) (hereinafter referred to as the Patent Law) and the Detailed Rules for the Implementation of the Patent Law of People’s Republic of China (PRC).

the second Where a patent mark is marked, it shall be marked in accordance with these Measures.

Article The department in charge of patent work shall be responsible for the supervision and management of the act of marking patent marks within its administrative area.

Article 4 During the validity period of the patent right after the grant of the patent right, the patentee or the licensee who has the right to mark the patent mark with the consent of the patentee may mark the patent mark on the patented product, the product directly obtained according to the patented method, the packaging of the product or the instruction manual of the product.

Article 5 Where a patent mark is marked, the following contents shall be marked:

(a) indicate the categories of patent rights in Chinese, such as China invention patent, China utility model patent and China design patent;

(2) The patent number granted by China National Intellectual Property Administration.

In addition to the above contents, other words and graphic marks may be attached, but the attached words and graphic marks and their marking methods shall not mislead the public.

Article 6 Where the patent mark is marked on the product directly obtained by the patented method, the packaging of the product or the instruction manual of the product, it shall be indicated in Chinese that the product is obtained by the patented method.

Article 7 Where the patent right is marked on the product, the packaging of the product or the manual of the product before it is granted, the category and patent application number of the patent application in China shall be marked in Chinese, and it shall be marked.The words "patent application, not authorized".

Article 8 Where the marking of patent marks does not conform to the provisions of Article 5, Article 6 or Article 7 of these Measures, the administrative department for patent affairs shall order it to make corrections.

Where the improper labeling of patent marks constitutes counterfeiting, the administrative department for patent affairs shall punish it in accordance with the provisions of Article 63 of the Patent Law.

Article 9 China National Intellectual Property Administration is responsible for the interpretation of these measures.

 Article 10 These Measures shall come into force as of May 1, 2012. On May 30, 2003, China National Intellectual Property Administration Decree No.29 issued the Provisions on the Marking Methods of Patent Marks and Patent Numbers, which shall be abolished at the same time.

How to settle the invoice? What are the procedures and precautions for invoice settlement?

In the insurance business, invoice settlement is very important. It is not only a key link in the financial process, but also an important step to protect customers’ rights and interests and the company’s compliance operation. The following will introduce in detail the specific process of invoice settlement in insurance business and matters needing attention.

First of all, before the invoice settlement, we should make full preparations. This includes collecting and sorting out relevant insurance business information, such as insurance contracts, premium payment vouchers, claims records, etc. These materials are the important basis for issuing and settling invoices, and ensuring the integrity and accuracy of the materials is the basis for smooth settlement. At the same time, it is necessary to confirm the authenticity and compliance of the business and avoid invoice problems caused by false business.

The next step is the invoicing process. Generally speaking, insurance companies will issue different types of invoices according to business types and customer needs. Common ones are special VAT invoices and ordinary VAT invoices. When issuing an invoice, you must fill in the invoice information accurately, including customer name, taxpayer identification number, insurance items, amount, tax rate, etc. Any information error may lead to invalid invoices or bring tax risks to customers. In addition, the invoice issuing time is also stipulated, which should usually be issued in time after the premium is received or the claim payment is paid to ensure the timeliness and accuracy of financial data.

After the invoice is issued, it enters the settlement process. The insurance company will deliver the issued invoice to the customer, and the delivery method can be paper invoice mailing or electronic invoice sending. For paper invoices, to ensure the safe and timely delivery in the mailing process, you can choose a reliable courier company and keep the mailing certificate. The electronic invoice should be sent to the effective mailbox designated by the customer and confirmed that the customer has successfully received it. After receiving the invoice, the customer will check and confirm it. If the invoice information is correct, the customer will carry out corresponding financial treatment, such as accounting and deduction. If there is a problem with the invoice, the customer should communicate with the insurance company in time, and the insurance company needs to correct and reissue it in time.

In the whole process of invoice settlement, there are some important matters needing attention. The following is explained in detail through tables:

matters need attention Specific content Compliance Strictly abide by the national tax laws and regulations and the relevant provisions of the insurance industry to ensure that the issuance and settlement of invoices meet the legal requirements. Data security Protect customers’ invoice information and financial data, and prevent information leakage. Communication and coordination Insurance companies should maintain good communication with customers and solve problems in the process of invoice settlement in time. Archive management Keep proper records of invoice issuance and settlement for subsequent inquiry and audit.

In a word, invoice settlement in insurance business needs rigorous process and high sense of responsibility. Insurance companies should ensure that every link is accurate, and customers should actively cooperate to complete the invoice settlement work together to ensure the smooth progress of insurance business.

(Editor: Wang Zhiqiang HF013)

[Disclaimer] This article only represents the author’s own views and has nothing to do with Hexun. Hexun.com is neutral about the statements and opinions in this article, and does not provide any express or implied guarantee for the accuracy, reliability or completeness of the contents. Readers are requested for reference only, and please take full responsibility. Email: news_center@staff.hexun.com.

Gongda Yan: Reflections on Contemporary Calligraphy Culture

  editorial comment/noteThis article is selected from the collection of "2019 China Higher Calligraphy Education Forum". From the artistic creation of contemporary young and middle-aged calligraphers, it comprehensively combs the basic situation and characteristics of the calligraphy world, the existing "common faults" and the remedies for rectification, so as to comprehensively expound the current calligraphy ecology, the aesthetic way of contemporary creation and the promotion of Chinese aesthetic education spirit, and make clear the direction from the philosophical speculation of art to complete the task of creative transformation and innovative development.

  Creativity and gains and losses — — Discussion on the Artistic Creation of the Book Circle at Present

  With the 40 years’ reform and opening-up in China, today’s book world has seen a scene of all-round prosperity, and it has also trained a group of elite talents. They are self-confident, mature and enterprising! In the history of China’s calligraphy, this is undoubtedly a special cultural phenomenon. Young and middle-aged calligraphers in today’s book world have been tempered and become the main force in today’s book world. They are energetic in artistic creation, active in aesthetic thinking, rich in integration orientation, solid in traditional pen and ink, and novel in form creation … … The broad vision and multi-dimensional perspective confirm that they are explorers and practitioners who are heading for the ideal world in today’s noisy and complicated book craze. In a certain sense, it can be said that the artistic practice of this generation of young and middle-aged calligraphers has made today’s China book world richer and more energetic. To sum up, the artistic creation of today’s book world presents four characteristics:

  The first is the call for the return of tradition.Whether it is the study of calligraphy, the study of steles or the integration of steles, the China calligraphy circle has gradually moved towards stability and health in the past forty years. Multi-approach and colorful unity, whether it is the style of two kings, the style of Ming and Qing dynasties, the style of bamboo slips and so on, are all a return to tradition. Returning to tradition is not copying tradition. Many works in previous national exhibitions have shown a strong style of personalized artistic language symbols on the basis of tradition, highlighting the cultural concept of advancing with the times in contemporary art exploration, which is the main theme in today’s life aesthetics.

  The second is the degree of form innovation.Needless to say, the exhibition era needs the diversification and richness of the exhibition forms of calligraphers’ works. With the opening of society and the diversification of aesthetic ideas, the space art of calligraphy has added the fashionable color of plane composition, which is the inevitable aesthetic demand of the public today. Once upon a time, due to the multi-layer effect of social fast food culture and fashion pursuit, fresh, exciting and colorful "surreal" and "ancient relics" filled all kinds of national book fairs, which seemed to have become the established custom of visual effect adjustment in the exhibition hall conduction space … … With the passage of time and the deepening of professional artistic creation, the works of the national exhibition have gradually moved towards simplicity and nature, and returned to the true nature of the natural writing of Chinese characters.

  The third is the strengthening of freehand brushwork poetry.The extension of calligraphy, the pursuit of interest, personalized creation, boldness, agitation, publicity and unrestrained … … It embodies the mainstream style of aesthetic feelings in the current book world. At the same time, with the complementarity, reference and integration in the inheritance of calligraphy, all kinds of freehand brushwork styles with strong personality consciousness are gradually formed. Regular script is integrated into the meaning; Borrowing from seal to grass; The cursive script (big grass) structure is open and closed; The cursive script is interactive and gradual; The effective exploration, the transformation of ideas and the birth of interest have become the remarkable characteristics of young and middle-aged calligraphy creation today.

  The fourth is the improvement of humanistic quality.A gratifying phenomenon is that many authors have gone far beyond the single calligraphy skill training and entered the in-depth study of Chinese traditional poetry. The phenomenon of the author’s self-written poems and the in-depth study of ancient calligraphy theory presented in various exhibitions indicates the comprehensiveness of calligrapher’s cultivation.

  It is true that we must face up to all kinds of problems and tendencies in contemporary exhibition works. This is the "common fault" in China’s calligraphy creation at present. In short, I think there are four aspects that must be paid attention to:

  First, despise brushwork. The calligraphy theories of past dynasties have strict and high standards for using pen and ink. As an internal form of calligraphy, brushwork is the most important. Some works in all kinds of exhibitions in China pay more attention to form than connotation; Pay more attention to interest than line quality. The brushwork is arbitrary and the brush array is mixed. For example, the seal script is out of balance and the loan is improper. According to Liu Xizai’s "A Brief Introduction to Art", reverse entry, astringency and tightness are the keys to writing. When writing seal script, the word "astringent" is often ignored, and the brush is dragged along the stroke, not to mention wrapping the front and turning it around, which goes against the trend. The big grass is to make the degree of transition and the actual situation suitable. If you don’t know how to use a pen, you will often open and close the switch casually, resulting in exaggerated spatial layout. The midline is thin and erratic, and the reality is improper. Confuse the brushwork of big grass and small grass, and get lost in the unconscious state. Ou Yangxun’s "On the Use of Pen" "The experience of using a pen by a husband must be hooked and glued, and the ladder will not be wasted, so there must be a reason. Wandering and pitching, tolerance and airflow. " Dong Qichang’s "Essays on Painting a Zen Room", "Where you send a pen, you must be able to raise it and not let it suppress itself … … If you don’t trust the pen, you will have a master at every turn. The word "turn" and "beam" is a clever tactic for calligraphers. Today’s people are only masters of the pen, and they have never carried a pen. " Liu Xizai’s "An Outline of Art and Books" "The calligrapher is in agreement with the word" press ",but there is no separation. Therefore, it is necessary to lift the pen when it is heavy, and press it when it is light, so as to avoid falling and drifting. " These classic book theories of the ancients,How important it will be to today’s calligraphy art creation! We can see that in the exhibition, some cursive works are full of papers and clouds, full of romantic ideas, and the brushwork is mixed. Even Lian Bi didn’t mention it, so they just dragged their feet. In addition, the "twisting" in the calligraphy style is different from the pen tip. The writing style of small characters is used to write large characters casually, and the linearity of small characters is used to replace the linearity of large characters. This phenomenon is more prominent in many works. It should be said that the art of calligraphy needs form and pays attention to momentum, but it is also based on linear essence.

  Second, the ink is single. As the ancient saying goes, "Calligraphy is only difficult to reach with charm", and its key lies in the richness and variability of pen and ink. At present, there are many people who neglect to use ink in calligraphy, especially in the creation of seal script, and the ink is generally too solid, and even the ink method has not changed throughout. "Where there is power in the dark, there is not enough time in the white" is the critical remark made by Mr. Huang Binhong when he first met Lin Sanzhi at the age of 32. The method of using ink is thick, light, moist, thirsty and white. Its main point is that "with dryness, it will be moist, and it will be dry" (Sun Guoting’s Book Spectrum). With dryness, it will be moist, and with concentration, it will show its strength. In the brushwork, it will show ink colors and ink tones and enhance the artistic expression of calligraphy. I am eager to live, but I am eager to be gorgeous. I am eager to take risks, and I know how to keep black. At present, many calligraphers’ ideas have not broken through the barriers of epigraphy in the Qing Dynasty, and they have inherited the habit of using ink in the Qing Dynasty, and they are not good at and dare not use thirsty ink. "Dry front, namely thirsty pen. The calligrapher’s double pipe has the word "dry pen", which is totally different. If you are thirsty, you will not be moist, and if you are dry, you will die. " (Liang Tongshu’s "On the Book of Polo Temple") The way to thirst for ink is to use water. "The cleverness of operation lies in one heart", the thirsty pen uses less ink, the astringent pen is retrograde, and it is vigorous and vigorous, writing out the white silk in the stippling. In the application of thirsty ink, it is often inseparable from astringent pen. The pen is awkward, the mistake is difficult, and there is something left in the line. Cai Yong’s "Nine Potential" said, "The astringent potential lies in the tight method of fighting.The ancients said, "If you support a water boat, you will try your best to stay where you are.". Mr. Lin Sanzhi put it well in Talking about Art — — "Huai Su can seek a pen without ink, and write embellish in dry pen, and the bones and muscles are among them." "The monument depends on the blank space" and "seek cleanliness in chaos, and distinguish between black and white". He also said: "The most difficult thing to change from rigidity to softness in the Book Score is to write insect-eaten lines, and the strokes are like insects." Hiding the show in the sky is really pale. Our era today is neither in the Qing Dynasty nor in the Tang Dynasty. I thought today was an era of freehand brushwork and fiction. Zhuangzi’s "emptiness", "quietness" and "clearness" and Laozi’s "striving for emptiness, keeping quietness and fidelity" also require us to realize today that a good work must emphasize emptiness, not reality.

  Third, the gas cell drops. Calligraphy is most bookish. The ancients often warned future generations with the words "calligraphy and painting should be viewed as rhyme" and "the calligrapher’s pen is precious". "Vivid charm" is the first of Sheikh’s "six laws". Guo Ruoxu commented in the Northern Song Dynasty that "the six laws are refined, and it is not easy to last forever". Qi and rhyme have always been the philosophical speculation of China’s calligraphy art and the main theme of his calligraphy creation. At present, the problem is to oppose charm and form, pay attention to stippling skills and ignore breath rhyme. Or the form is exaggerated too much, or the artistic realm is degraded by pursuing the superficial interest of pen and ink too much. We can see that many works in various exhibitions emphasize publicity, lose purity, blindly pursue individual style and ignore the artistic character of the works. As a result, the book is familiar and the weather is weak. Zhao Huanguang commented in "Cold Mountain Broom Talk" that "the article is based on the system and the sound is the tone; The style of writing is the case, and the front is the tone. If it is not ancient, it will be vulgar, and if it is not rhymed, it will be wild. " This just proves that all literature and art take Qi as the most important. "The ancient quality of this article also, the base quality and your article. Writing is easy to change, which is in line with deep feelings. Those who are qualitative are like classics, and those who are literate are like weft. If Zhong and Zhang are branches and two kings are Chinese leaves, beauty is beautiful … …” (Zhang Huaiguan’s "Six-body Calligraphy Theory") Pen and ink skills are rooted in subjective feelings. Pen and ink is the mind of writing people, although it comes from the hand, it is rooted in the heart.The ancients commented "… … I am full of meanness, and I am at ease. I feel sorry for my feelings. How can I rush to the God of Mu? " Therefore, only when the heart is mellow can the pen be harmonious, and only when the mind is aware can the pen be hot.

  Fourth, the innovation is superficial. "Change" is the basic law of China’s calligraphy development. Today, the survival significance of calligraphy has changed from practical value to artistic function. The original "daily writing" of calligraphy has become "artistic appreciation". Therefore, today’s calligraphy should be based on artistry, not only linear schema, but also the appeal of humanistic spirit. We advocate "natural writing", which means to express a high degree of artistry in accordance with artistic laws and theories, aesthetic elements and laws. Taking Mr. Lin Sanzhi as an example, he stated in "Self-Narration" that his cursive script "takes two kings as the mantle, Huai Su as the ancestor, Wang Juesi as the friend, Zhu Xizhe and Dong Xiangguang as the guests". We can see that Lin Lao’s creation entered the realm of transformation in his later years. Appreciating his cursive works when he was 90 years old, he showed a scene of turning long into short, making a living from maturity, turning a circle into a square, turning a connection into a break, turning complexity into simplicity, and turning reality into emptiness. It can be seen that it is not easy to change the times of calligraphy. It is not a single form change, but a transformation of the essence and the elevation of the spirit. At present, some works in the exhibition show off their skills one-sidedly, learn from the ancient and superficial, and take a superficial approach. "Innovation" is only a superficial visual effect. From writing to painting, we only seek the prominence of personality style, the publicity of modern consciousness, the exaggeration of form and the neglect of essence; Or on the basis of an ancient calligrapher’s style, enlarge the fine brushwork into a large-character paradigm and change the form.As a result, the lines are stiff and wavy, the ink is dignified and there is no real or false care, and the charm of the works is insufficient, which obviously lacks vitality and vitality. I think that the artistic innovation of an era must organically integrate the traditional characteristics, the characteristics of the times and the characteristics of individuality, and rationally verify the aesthetic characteristics of calligraphy art with China’s traditional philosophy, so as to complete the construction of personal artistic style.

  To sum up, the current calligraphy art creation must deal with the triple relationship, namely: the persistence of tradition and the promotion of modernity; Strengthening of skill and poetic expression; The variety of forms and the attention to the essence. The social aesthetics of "the person with strong spirit comes first, and the person with beautiful function comes second" will be strengthened in the life aesthetics in the new period. This is the cultural spirit of "style and feelings are the first, technique is the second", which will be further paid attention to.

  Burst and loss — — Thoughts on the current calligraphy ecology

  In the past 40 years of reform and opening up, China’s calligraphy has experienced a period of exploration and development from traditional study art to public display space; It has experienced a stable and deepening period from the pursuit of artistic visual form to the modern transformation of classic techniques; It also went through the period of cultural thinking when artistic creation thought pursued to the integration of form and content. This course just proves that calligraphy art, like other national arts, is a part of the aesthetics of popular cultural life. With the advancement of reform and opening up, the art of calligraphy is constantly evolving and improving with the evolution of social ecology and the demands of people’s spiritual world.

  Forty years of "calligraphy craze" has contributed to the mass calligraphy movement that has never been seen before in the history of China, reflecting the mass psychology and aesthetic pursuit carried by contemporary culture since the reform and opening up, and expressing the "road map" that the mainstream culture of contemporary calligraphy will inevitably advance. This has painted an extremely splendid page for the contemporary culture of China! However, it goes without saying that in the period of social transformation with rapid economic development and great changes in people’s life forms, our nation did not construct the cultural ideal of the times in advance or at the same time, resulting in the alienation of social value judgment and behavior orientation into the standard of "time is money", while the ultimate direction of cultural value and cultural creation fell to the price index.

  It should be noted that the 40-year contemporary "calligraphy craze" has undoubtedly brought about the prosperity of mass culture and the inheritance of national lifestyle, but also brought about the diversity of values and the search for leisure interests. It is manifested in the shift of some national cultural positions of calligraphy, the subversion of traditional artistic value system and the lack of aesthetic judgment standards.

  Over the years, there are also various unsatisfactory places in contemporary book circles: impetuous mentality, flashy art, grandiose form, superficial comments and superficial communication. The artistic fashion is clamoring, the creative spirit is mediocre, the classic calligraphy is alienated, and the core values are stolen … … In the pervasion of the utilitarian consumer market, which is characterized by diverse social patterns but so homogeneous, the poverty of philosophy, the lack of culture, the pallor of thoughts and the danger of the traditional lifeline being connected and broken are approaching us at all times … … All kinds of phenomena embodied in artistic creation, such as the supremacy of form, the phenomenon of "ugly books", the expansion of customs and the aphasia of criticism, give the majority of calligraphers a wake-up call and reflection!

  Then, the fundamental reason why calligraphy spreads these phenomena is the imbalance of social and cultural ecology.

  Since the reform and opening up, contemporary calligraphy has entered an unprecedented artistic and historical transition period from inheritance to innovation, and also faced a secular generalization period of social and cultural ecological crisis and loss of humanistic spirit under the vigorous development of market economy. When we look back at the colorful history of contemporary calligraphy today, we can’t help sighing for the promotion of the two levels, with mixed feelings. The collision of various artistic trends of thought and the dispute of schools have made calligraphers of all walks of life step into the wrestling field of artistic innovation and change with great energy, and explore and analyze the track of the evolution and development of wave after wave of calligraphy style … … Such a noisy book world is rich and varied, vivid and vulgar. East and west, conservative and innovative, all kinds of ideas meet and collide with each other. In the vanity fair of social and economic transformation, impetuousness and shallowness, eagerness and urgency often make people feel confused and helpless in the interweaving of multicultural ideas! People can’t help questioning again and again: Have we lost our introspection and awe about tradition, and lost our responsibility and prospect about the times?

  It is true that from the historical point of view, the forty-year "calligraphy craze" has provided such rich dramatic changes and intriguing cultural thinking for contemporary social art. Isn’t this the joy and loss anxiety of a win-win situation with social development in the "natural growth period" of today’s book world?

  "Lost anxiety" is unavoidable! On September 30th, 2009, China’s calligraphy China seal cutting was successfully applied for, and the national calligraphy craze rose again, which is undoubtedly a good thing. "National Calligraphy" has brought great impetus and prosperity to the study, communication, popularization and dissemination of traditional calligraphy art, won a broad social space for calligraphy as the inheritance of the Chinese people’s lifestyle for thousands of years, and demonstrated the spiritual appeal of mass life aesthetics for the return of traditional culture.

  However, we can’t help but seriously reflect on the essence and trend of this "socialization" from the many works of "national calligraphy" exhibition, dissemination and even transaction — — The first is the generalization of artistic ontology. It shows contempt for classics, giving up the basics, vulgarizing and inheriting, crude imitation, deviating from the law of artistic creation, and lacking the spirit of great country craftsmen. Calligraphy exhibition only seeks to publicize the prosperous landscape in the noisy downtown. The manufacturability replaces the purity of traditional natural writing. The second is the generalization of creative mentality. People are no longer calm and indifferent, but they are used to competing to express themselves in the heat wave of calligraphy display, auctioning "achievements", packaging and dressing up, and publicizing their individuality. Impetuousness and urgency, superficial fame and small profits … … In the traditional sense, the aesthetic of elegance and quietness has been eliminated by socialization. The third is the generalization of cultural values. Art speaks by height. We need width, but we need depth and height more. The "prosperity" of virtual fire’s national calligraphy can only bring us profound lessons! History does not allow to confuse calligraphy with non-calligraphy in the generalization of social art.

  When we look back many years ago, when the situation of "socialization" spread rapidly and competed for beauty, we can see that the readability, amiability, preciousness and appreciation of traditional calligraphy art have gradually moved towards the vulgar, charming, strange and hateful behavior process of performing arts, and calligraphy has gradually moved from the self-cultivation of national culture to the dilemma of social entertainment & HELIP; …

  Therefore, we should stick to the aesthetic bottom line of China’s calligraphy, the reverence and piety of national culture, and the character and integrity of intellectuals in the new era, which requires us to look up to historical classics and safeguard the nobility and dignity of calligraphy culture. We should seek a reasonable fulcrum for the integration of tradition, times and individuality, purify and enhance the "sociality" and aesthetic height of national calligraphy, and carry forward China’s humanistic character of combining beauty and use with knowing and doing.

  Today, when we rationally analyze the social ecology of contemporary calligraphy, we first need to return calligraphy as a national culture to the identification of social value system. There must be a threshold for understanding and expounding the artistic language of calligraphy, and non-calligraphy language cannot be tolerated. Without tradition, just as a nation loses its orthodoxy, its nationality and purity disappear; Without self-discipline, calligraphy language will have no rules of its own, and the art of calligraphy will inevitably be artificially distorted. Therefore, the relationship between calligraphy language and creators is temperature, strength and depth. Only by sticking to the bottom line can we win the height of social and cultural popularization in the times.

  Tolerance and choice — — The aesthetic way of artistic creation in the times

  In the new era, we advocate pluralism and tolerance. So, what is pluralism? Pluralism is not only the free expression of different views, but also the consensus among dissidents, the consensus on social core values, and the unanimous recognition of the rules of the game. Without the recognition of values and rules, pluralism will lead to the chaos and disintegration of the art world.

  The emergence of pan-aestheticization has expanded the diversity of aesthetic forms. The beauty, sublimity and harmony of traditional classical aesthetics have been broken by the "contemporary art" introduced by the west. It dispels the standard of Chinese traditional aesthetics and subverts the cultural standpoint of traditional aesthetics. The works made by reproduction, technology, decoration and craft, with mass media as the main means, are filling the current cultural space and art market and supporting the increasingly secularized popular aesthetics.

  The change of contemporary artistic concept also directly affects the purity and spirituality of traditional calligraphy art. From "contemplation" to "noise", from "aesthetics" to "appreciation of ugliness", from elegance to vulgarity, from simplicity to vulgarity … … This is the shadow of western postmodernism’s attitude towards traditional culture with historical nihilism, which has caused the growth of liberalism in the book world.

  Postmodernism, as an irrational thinking, forces art to extend in the direction of alienating cultural values such as "canceling the subject without aesthetics", which dispels the original aesthetics and sublimity of artistic creation, confuses the differences between eastern and western cultures and blurs the public’s judgment standards on artistic aesthetics. In order to show the form, we deliberately ignore the quality, fade the quality, create novelty, attract the attention of the public with unconventional "arguments" and unconventional behaviors, and form a "landscape". Whether it is painting or even calligraphy, grotesque and disorder are the selling points, ugliness is the appeal, and mainstream values are the criterion, which can not but arouse high vigilance and reflection in the painting and calligraphy circles!

  It is true that we should have a clear and clear appraisal of "ugly books". The "ugly book" we refer to here is a bad phenomenon that breaks away from the noumenon law of calligraphy art creation and the structural norms of Chinese characters, ignores the basic rules of calligraphy art such as brushwork, takes the pen as the body, gathers ink to form, is vulgar and vulgar, and is crazy about "creating new things". The "ugly book" referred to here should be distinguished from the "making risks" and "committing risks" in the artistic creation itself.

  Generally speaking, artistic creation must be pursued from justice to danger, and then restored to justice. Liu Xizai’s "A Brief Introduction to Art" points out: "Learners begin by asking for work without work, and then ask for work without work. Those who don’t work are extremely hardworking." He also pointed out: "Common books are not for beauty, so they are ugly." It should be said that there are certain rules in the form composition and internal quality standard of the high realm of "work seeking not work" in art, and its visual space has a certain degree. "Not working" is not "ugly", but "creating risks".

  There is no doubt that various cultural phenomena are inevitable in the interweaving of diverse and scattered social and cultural trends of thought, and there is no need to be puzzled or surprised, not to mention spreading hype or even infinitely magnifying it into "news events" through mass networks. We need to firmly allow some (or even several) calligraphers to make independent and innovative "artistic experiments" with an inclusive attitude, and the book world needs understanding and dialogue. These (few) calligraphers already have profound experience in traditional pen and ink skills and artistic creation. They have found a new way to prove new ideas and explore the "art of mind". Different people have different opinions, and the wise have different opinions, so they can be tested by practice.

  Obviously, in the current social and cultural transformation in the context of globalization, how to maintain and reshape the identity of China’s calligraphy culture? This requires a choice based on tolerance. The temporality of art criticism has been deposited into three major anxieties, namely, concept anxiety, identity anxiety and reality anxiety. How to make the real "problem consciousness" show clear criticism? How to make theory reveal and guide contemporary artistic creation practice more directly and effectively? How to strengthen the function of literature and art to "educate and change customs" and correct the present situation of entertainment and marginalization of elite culture under the market economy? These are all urgent problems to be solved.

  Today, 40 years after the reform and opening up, it is worthwhile for the calligraphy circle to further understand the cultural connotation of modernization, the traditional cultural complex of China in the process of modernization and the value orientation of China’s cultural development today. Five thousand years of Chinese culture tells us that the "core value" of culture is one of the most important reasons for the continuity of Chinese civilization. This core value is constantly changing, enriching and developing, and forms the core value of the culture of the times in the relative period. Forty years of reform and opening up, its core is to guide the society to establish a leading value, that is, to promote modern humanistic spirit. This requires the calligraphy circle to adhere to the global vision and localization practice. The construction of the aesthetic evaluation system of contemporary calligraphy creation is also the aesthetic basis of the classic works of the birth era. Facing the challenge of consumer culture, we should strive to enhance people’s aesthetic taste and promote the transformation of social aesthetics to elegance. We should consciously lead an aesthetic value judgment scale, summon the return of literary responsibility and lead the promotion of national spirit.

  Cultural consciousness is the requirement of today’s times, which is a kind of aesthetic consciousness and mentality of cultural subject reflected in cultural reflection, cultural creation and cultural practice. As a calligraphy circle, the fundamental purpose of cultural consciousness is to strengthen the independent ability of cultural aesthetics and obtain an independent position to adapt to the cultural choice of the new era. We are in favor of such cultural consciousness — — Under the impact of the wave of globalization, it will never stick to the old ways and cling to the shortcomings, but keep pace with the times, actively fight, select the best and eliminate the bad, and advocate that all countries and nations in the world have symbiotic equal opportunities for culture and art and the tolerance of "beauty of beauty, beauty of beauty, harmony of beauty and harmony of the world". Calligraphy artists in this era especially need ideological nourishment and aesthetic purification. The times need calligraphy artists not to be eager for quick success and instant benefit, but to think about the deep-seated issues of contemporary culture and social aesthetics and the humanistic spirit of the times. Its essence is firstly the humanistic rationality in the contemporary aesthetic orientation and orientation of calligraphy art. As an important duty of aesthetic culture, calligraphy art is not to satisfy people’s recreational function of venting their senses, but to rise to the realm of free life, purify people’s souls and cultivate good daily quality. Therefore, today, every artist in the Republic of China should seriously reflect on his responsibility to society and mainstream culture. This is to rebuild the artistic evaluation and value system with national character and style of the times, and to create works of art with China style and China spirit.This is our strategic choice in the aesthetic way of artistic creation in the era of economic globalization and cultural diversification, which is also the cultural consciousness of contemporary calligraphy art!

  What is the most lacking in the context of contemporary China calligraphy culture? Is to guide the society to establish a dominant value. We must clearly see the aesthetic transformation of contemporary calligraphy art, deepen our understanding of traditional techniques and classics, and expand the composition of artistic forms. This is the innovation that is good at organically integrating the characteristics of tradition, the characteristics of the times and the characteristics of individuality, that is, "bringing forth the old and bringing forth the new".

  We are facing the "new era" of Internet media with such a huge audience and the commercial circle of citizen consumption culture with leisure and ridicule as the basic mode. The reality makes us awake: the most fundamental significance of art lies in the pursuit of non-utilitarian transcendental value. At present, the primary premise of our pursuit of classics is not to compromise the consumption culture of the market and not to succumb to the unequal value system manifested by money!

  Philosophical thinking and activation — — Thoughts on carrying forward the spirit of Chinese aesthetic education

  Every nation in the world has its own writing and culture, which shows the description of its national personality. Chinese characters are the representatives of Chinese national culture, the high materialization of China’s traditional philosophy, and the basic spirit of Chinese culture is condensed at the simplest level. Mr. Lin Yutang said: "In calligraphy, perhaps only in calligraphy can we see the perfection of Chinese’s artistic soul." We say that the artistic image created by Chinese calligraphy is not only the beauty of Wang Xizhi’s visit to Lanting, but also the pain of Yan Zhenqing’s desperate service to the country; Is it the confusion of Su Dongpo’s cold food in Huangzhou, or the combination of Sun Guoting’s books and essays … … It is an aesthetic state of human life and a life image of human philosophy. Calligraphy embodies the humanistic spirit of human self-care and pursues the ultimate realm of oriental aesthetic ideals. In the pursuit of human perfection and respect for people’s own value, calligraphy aesthetic education has led people to find a way.

  The construction of the core value system of contemporary calligraphy must be based on the ontological law of calligraphy culture and the scientific understanding of social development, and leading the aesthetic direction of contemporary calligraphy fundamentally requires philosophical thinking.

  For a long time, human beings have never stopped exploring the essence of beauty to awaken people’s most straightforward memories of world things. As a unique cultural memory of national spirit — — Calligraphy, what do we stick to today? Create what? This is the first question that calligraphers should answer. Regression is not a copy, and the beauty of tradition cannot invariably replace the pulse of today’s times! Artists who cannot enter "creative transformation and innovative development" will eventually become outcasts of the times. We say that philosophy is the "third wisdom" among science, art and philosophy. At present, the "symptomatic treatment" in the book circle needs "philosophical classics", and it needs China’s traditional philosophy to think about the times of contemporary philosophy, which gives birth to "wisdom scheme". This "wisdom" is a theorem and the "third wisdom" to reshape the oriental beauty, which indicates the strategic orientation of the aesthetic spirit of contemporary calligraphy.

  After the evolution of Chinese characters’ calligraphy style, the aesthetics has also entered a period of cultural consciousness. Jin Shangyun, Tang Shangyi, Song Shangyi and Ming and Qing Dynasties are the aesthetic demands and artistic expansion in different historical stages, which are always developed around the core concept of the Chinese nation "the golden mean" in China’s calligraphy. The basic spirit of China’s calligraphy is as stated in the Book of Rites: "A gentleman respects virtue and asks for knowledge, which is broad and subtle, extremely clear and moderate". In view of this, the "golden mean", "moderate" and "extremely bright" have become the core concepts of China’s freehand brushwork spirit. Laozi’s "Tao is natural", Zhuangzi’s "only Tao gathers emptiness", Laozi’s "Xuan Jian" and Zhuangzi’s "Xin Zhai" and "Sit Forgetting" have become the "bulk" of China’s art for thousands of years. This "big book and large quantity" is the guide to pursue the aesthetic realm of calligraphy today. Taking the cursive script as an example, the tradition of taking calligraphy from the works of Wei and Jin dynasties, represented by the "two kings", constantly recombines its genes with the great culture of each period, forming an inexhaustible motive force for the continuous development of calligraphy, and its essence always presents constancy.Whether the style of calligraphy is simple, vigorous, cold, strange and vertical, or simple, elegant, harmonious and indifferent, it makes people understand that calligraphy must be rooted in tradition, and the classic "learning from ancient times" training process of calligraphy inscriptions is actually the tempering process of "people" as a member of society.

  As the aesthetic consciousness of contemporary calligraphy art, perhaps we can put forward such a coordinate system — — Its vertical axis is to look at the future trend of China calligraphy from the combination of tradition and innovation, which is a time axis; Its horizontal axis is to find the aesthetic orientation of calligraphy art in the current globalization context and determine the significance of its existence in the times. This is a spatial axis. This is a cultural reflection on the artistic function of calligraphy, and an accurate grasp and inevitable choice of the law and characteristics of artistic development. It can be seen that the development of contemporary calligraphy will depend on the construction of aesthetic scientific evaluation system of calligraphy creation. The "science" here is not the "science" of natural science, but the "timeliness and appropriateness" in the philosophical sense, that is, the "golden mean" concept. The construction of this artistic standard and evaluation system must be rooted in the fertile soil of Chinese aesthetic spirit.

  The Chinese aesthetic spirit is rooted in the life charm of national philosophy and the poetic tradition of national culture, and has established a Chinese aesthetic system with humanistic care as the core, great beauty as the field of vision, beautiful scenery and high interest as the purpose, focusing on the aesthetic spirit of blending truth, goodness and beauty.

  The present is an era that needs philosophy, needs ideas, and will certainly produce ideas. There has long been a one-way thinking of binary opposition in China’s literary and art circles. In the past, literature and art were subordinate to politics and aesthetic thinking was replaced by political thinking; Now, under the condition of market economy, literature and art are subordinate to economy, and aesthetic thinking is replaced by profit thinking. This one-way thinking of aesthetics is morbid, and it is also manifested in the tendency to go one-sided and extreme in dealing with the cultural relationship between China and the West. As President Xi pointed out, some people respect foreign things, follow foreign things only and take foreign things as beauty, and are keen on de-China, de-ideology, de-value, de-historization and de-mainstreaming, and that set of "has absolutely no future". Similarly, it is useless to hold on to the historical heritage and dare not look far to absorb the excellent elements of world civilization.

  Carrying forward the Chinese aesthetic spirit is a philosophical proposition, which is the foundation of the development direction of contemporary China art. Professor Zhang Shiying from the Department of Philosophy of Peking University put forward the original aesthetic theories of the times, such as "beauty points to the lofty" and "the sanctity of aesthetic feeling", which played a leading role in rectifying the kitsch and utilitarianism of literary and artistic creation in the tide of market economy. From traditional philosophy to contemporary comparative study of Chinese and Western cultures, Mr. Zhang put forward the concept of "the unity of things and everything" to "the connection of all things", which embodies the creative process from culture to life wisdom, connects Chinese and Western cultures, pays attention to reality and adapts to changes. It embodies that the task of aesthetics is to cultivate independent personality and transcendental spirit, and it is the study of "realm".

  To carry forward the Chinese aesthetic spirit, we must grasp the following aspects from the perspective of contemporary philosophy: First, "harmony between man and nature" rather than "separation of subject and object", which is the basic spirit of China’s philosophy. The second is to treat Chinese and western art aesthetics with the thinking of the times of "all things are connected", and to clarify the significance of artistic imagination and emotional experience in aesthetic activities. "The highest task of philosophy is not to know the sameness, but to grasp the similarity." Aesthetics cannot be attached to science and alienated into technology. We must integrate the similarities and differences between Chinese and western cultures, and make sense of them, so as to devote ourselves to the cultural creation of the times. Contemporary aesthetics in China, which is in social transformation, should pay more attention to artistic aesthetic practice and pay attention to metaphysical philosophical ontology. Third, we must deepen our understanding of China’s ancient theory of "hidden show" (image theory) and the aesthetic tradition of implication. Pursue poetry and raise the realm of humanistic spirit. Beauty, in addition to paying attention to perceptual image and form, must also have a deeper connotation, which lies in the value of showing the highest meaning of life. This is the "sacredness" of Heidegger’s "clear realm". Therefore, "the sanctity of beauty" means that the beauty of lofty realm is the support of spiritual beauty, not the beauty of simple things and the beauty of entertaining people’s eyes and ears.

  Carrying forward the guiding significance of Chinese aesthetic spirit in artistic practice: First, advocating both form and spirit, not just the supremacy of form. The cornerstone of Chinese aesthetic spirit is the connection between beauty and truth and goodness, and its core is the view of beauty with truth and goodness. Its ideal is the view of beauty with aloofness and lofty ideals, which advocates the aesthetic dimension with both content and form, and emphasizes the emotion, thought, character and mind of works. The second is to attach importance to the blending of reason and reason, and advocate implication and significance. The true beauty of art is the expression of true feelings and the prominence of personality. The freehand brushwork spirit of Chinese art is often not realistic, but a combination of reality and reality, with a lofty realm. The third is to highlight the beauty of life and carry forward the poetic character. The Chinese aesthetic spirit inherits the source of China’s philosophy, takes life as beauty, regards all things in the world as living beings, and advocates artistic life charm and poetic transcendence. It can be seen that Chinese aesthetic thoughts, theories and spirits have distinct national thinking and national theoretical signs. Chinese aesthetic spirit focuses on freehand brushwork. Beauty lies in the image, which breeds a series of aesthetic elements with national academic characteristics, including emotion, interest, environment, qi, rhyme, taste and taste.

  In a letter to a professor at the Central Academy of Fine Arts, General Secretary of the Supreme Leader proposed to carry forward the spirit of Chinese aesthetic education. This is the root of the development direction of contemporary China art. From aesthetics to aesthetic education, this is a process from the ontological characteristics of things to social communication and development. The ultimate goal of aesthetic education is to make the society and the public enter a lofty spiritual realm, a realm where the public can realize their own meaning and value of life, and a common realm of unremitting struggle for the great rejuvenation of the Chinese nation. This is the social responsibility shouldered by the vast number of literary and artistic workers in New China. The development of aesthetic education in an era is inseparable from the height of beauty spread by literary and artistic works created in this era. Therefore, to carry forward the spirit of Chinese aesthetic education today, we must follow the law of aesthetic education, be influenced by subtle beauty, and experience the fresh aesthetic activities of mass life in the new era, so that the whole people can improve their aesthetic quality, cultivate noble sentiments, shape a beautiful soul, stimulate innovative vitality and realize people’s all-round development.

  Calligraphy art is historical, humanistic and contemporary. Everyone who loves China culture should, as Laozi said, "know what is normal and restore life" and "in the final analysis, be quiet" when facing the ancient writing art, taste of china culture and artistic creation immersed in aesthetic experience, that is, to return to the original state of life, to the normal state, to explore the ontological law of calligraphy art in the historical evolution with a normal heart and a pure thirst for knowledge, and to trace the spiritual essence, humanistic concept and historical contribution of calligraphy art from the source of China culture. We should have a modern humanistic feeling of being grateful for the times, perceiving people’s livelihood, fearing tradition and living faithfully. You know, today’s cultural creation is tomorrow’s historical legacy. In order to achieve this, we must keep the right and change, and pursue the aesthetic character and cultural characteristics of the oriental beauty of China’s calligraphy, which is the ultimate way of calligraphy aesthetic education!

  Chinese traditional art has always advocated "change", which is what we call "innovation" today. "At the time of the meeting, people and books are old" in Book Score shows the importance of keeping the right and bringing forth the new. Change is to bring forth the new according to the law. This "new" is different from the style or genre of books. The "new" is a newborn born from the "ancient" mother, just like the blood relationship between mother and child has always been maintained. Keeping the right and changing is to follow the right path, the right pattern and the right pulse according to the artistic law. It is to restore calligraphy art to culture, seek truth from classics, lead in the direction, accumulate in the contemporary era, express the spiritual outlook and style of the contemporary people with pen and ink, and truly show the spiritual activities of the creators as a "meaningful form".

  Yes, when we are moved by the nearly perfect creative skills of the classics of past dynasties, you will naturally try to explore its formal origin and cultural genes, and gradually touch the background and personality spirit of the calligrapher. Therefore, the change must go beyond the purely technical level and go straight to the artistic spirit level. At this time, the creator will get the creative spirit of incomparable freedom, thus making the work have a deep appeal of aesthetic meaning. Therefore, to keep the integrity and change, it must take the Chinese humanistic concept as the fundamental fulcrum, and it has profound cultural connotation from the technical system to the internal spirit. It is the guide to create collective personality values and modern lifestyles in the new era.

  Socrates, the ancient Greek philosopher, said that "life without thinking is meaningless". Similarly, the so-called "formal innovation" and "artistic experience" that have not been tested by real time thinking and practice must be pale! Because "all human dignity lies in thought", the power of thought comes from that she is the cell of human belief. In the current growth environment of calligraphy art development, we must not ignore the phenomenon that "spiritual confusion" leads to "distortion of authenticity". Today, we inherit the spirit of Chinese aesthetic education, which is to continue the cultural lifeline of calligraphy itself, rather than to decorate the surface social life. Mr. Tsung i Jao’s philosophy of "never grinding one’s mind for ever, flowing freely in one’s heart" is precisely to clarify the philosophy of adapting to the situation and gaining the source of one’s heart. The creative spirit of contemporary calligraphy should not only "steal three points of pear flowers" from traditional classics, but more importantly "borrow a wisp of plum blossom soul". The spirit of China’s contemporary calligraphy aesthetic education is, on the one hand, the spirit of freehand brushwork contained in Chinese traditional philosophy, and on the other hand, it is a moving process of change. Its epochal nature can not only be confined to classical aesthetics, but also can not be derived from western modern aesthetic concepts. It is not a single pursuit of skills and the gradual change of formal beauty, but more from the aesthetic ideal, moral height and cultural value.Its spiritual core is a high degree of integration of advocating truth, goodness and beauty, which is a high degree of "people’s nature" in aesthetics. It should have a sense of national history, rich in national spirituality, national temperament and national language characteristics. It is the essence and soul of the collective aesthetic consciousness of the Chinese nation! A real artist’s aesthetic spirit lies in "integrating the past with me", and its artistic classicality must be the cultural creation of the times. Similarly, to carry forward the spirit of Chinese aesthetic education in the new era is to give full play to the unique advantages of art education, to enhance aesthetic quality in a strong cultural atmosphere, to innovate the vitality of techniques, and to realize the real and all-round development of students’ "sound personality" in the vivid practical experience of study and life.

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  Some thoughts:

  One reflection: Today, with the economic and social transformation, the generalization of social aesthetics of "national calligraphy" calls for the simultaneous construction of aesthetic ideals in China’s calligraphy era. How do we carry out "self-salvation" in our own cultural life and aesthetic pursuit?

  Thinking 2: Restore art to culture and seek truth from classics. Contemporary calligraphy needs the construction of the aesthetic evaluation system of the times and a cultural consciousness based on value inheritance and value innovation.

  Thinking 3: How to revitalize the excellent traditional art in the context of globalization? This requires the persistence of contemporary calligraphy culture and the reshaping of cultural identity.

  Looking around the book world, we need to stick to, develop and create a pure home that belongs to the local area and the times. "There is no definite taste in the big chapter, and there is no definite song in the general chapter". There are no two identical leaves in the world, and people can’t stand on the same river. Although there are different artistic styles and schools, there is always only one noumenon spirit of contemporary China calligraphy.

  Today, we can’t forget the original intention of starting to engage in calligraphy creation, research and education because of doubt, haste and competition of material status or fame. Looking at the disappearing back of the predecessors, we will really send out such a call from the bottom of our hearts — — What do we contribute to this era?

  (About the author: Gongda Yan, Professor Tsinghua University. Doctoral tutor, national first-class artist, expert enjoying special allowance from the State Council. Member of the 11th and 12th Chinese People’s Political Consultative Conference, Vice Chairman of the 5th and 6th China Calligraphers Association, Member of the National Academy of Painting of China, Vice Chairman of the National Education Calligraphy and Painting Association and President of the Higher Calligraphy Education Branch. )

Disputes over the sale of used cars are frequent. What does the law say?

  The online trading mode of used cars makes car sources and buyers more concentrated, reduces the circulation cost and facilitates buyers and sellers, but at the same time, disputes over the sale of used cars also occur from time to time, which leads to litigation rights protection.

  The evidence failed to prove that there was something wrong with the used car.

  The claim cannot be supported.

  ■ Case replay

  Zhao took a fancy to a second-hand car on a second-hand car trading platform, and signed the Purchase and Sale Deposit Agreement (that is, the car purchase format contract) with the owner Xu and the platform. The platform also issued the Re-inspection Report before the transfer, which showed that except for some external scratches, the vehicle’s power, steering, transmission, braking and other systems were temporarily normal. After picking up the car, Zhao wanted to transfer the vehicle to Chifeng City, Inner Mongolia, but it didn’t take long for him to get on the expressway to find that there was abnormal noise in the car. In order to prevent danger, he found that the front wheel bearing of the vehicle was cracked and the gearbox could not be upshifted, so he repaired the vehicle and replaced some accessories. In view of the maintenance cost, the after-sales staff of the used car trading platform said that this is not within the after-sales scope and will not be compensated. Zhao appealed to the court, arguing that the platform concealed the quality of the car condition and demanded compensation for maintenance costs of more than 10,000 yuan. After the court heard the case, all Zhao’s claims were not supported because the evidence could not prove the facts.

  ■ Judge’s statement

  The court held that the parties should provide evidence of the facts they claimed. In this case, if Zhao claims that the vehicle involved has quality problems and the vehicle parts need to be repaired or replaced, he should provide evidence to prove it, otherwise he will bear the legal consequences of failing to provide evidence. The Maintenance Order submitted by Zhao did not specify the reasons for repairing and replacing the parts. Therefore, it is impossible to see that the necessary maintenance was carried out because of the damage of the vehicle parts, and it is impossible to see whether the repaired and replaced parts were broken before Zhao picked up the car or were damaged after going on the road. Zhao did not submit the corresponding payment bills to prove that he actually paid the maintenance expenses. Therefore, the court could not support Zhao’s claim.

  When buying and selling second-hand cars, consumers must first confirm the condition of the car before paying the deposit. Before paying all the car purchase expenses, buyers must first confirm the condition and quality of the second-hand car they bought, the purchase period, whether it is an accident vehicle, and whether there are illegal acts that have not been dealt with. Secondly, if there are unreasonable terms in the format contract, such as expanding the transaction risk of one party, consumers have the right to request adjustments and modifications to the terms of the format contract. Finally, it is necessary to confirm the conditions and processes of providing after-sales service for used car trading platforms. If the second-hand car trading platform provides after-sales service for the vehicles purchased by the buyer, the platform is obliged to clearly inform them of the conditions and contents of providing after-sales service, as well as the repair reporting process and contact information, etc. If there are corresponding warranty cards and manuals, they should be issued to the buyer. If the vehicle is within the scope of after-sales service, the buyer shall report to the trading platform for repair according to the corresponding repair reporting channels and procedures.

  Platform fraud car seller

  The format clause was deemed invalid.

  ■ Case replay

  Ms. Zheng spent 90,000 yuan to buy a used car through a used car platform, and the dashboard showed that the mileage of the car was 49,000 kilometers. In addition to signing a car purchase contract, the second-hand car platform also provides an unsigned Second-hand Car Inspection Report as an annex to the contract. When Ms. Zheng sent the vehicle to the 4S shop for testing, she found that the actual mileage of the vehicle had reached 98,000 kilometers six months ago. She believes that there is fraud in the platform and appealed to the court, demanding that the other party pay 100,000 yuan in compensation. The second-hand car platform believes that it is only an intermediary company, and the sales contract signed with the plaintiff Ms. Zheng is entrusted by the actual seller. Moreover, in the test report, it is clearly stated that "the mileage indicated in the test report is for reference only, and no commitment is made to the actual mileage." The court held that there was fraud in the second-hand car trading platform, and the clause in the test report issued by it was a format clause and should be considered invalid. The judgment supported all the claims of Ms. Zheng.

  ■ Judge’s statement

  A standard contract refers to a pre-drawn contract for repeated use by the parties without consulting the other party when concluding the contract. According to the law, if the party providing the standard terms has the obligation to prompt and explain, it should draw the attention of the other party to the terms that exempt or limit its liability, and explain them according to the requirements of the other party. The standard terms that exempt the party providing the standard terms from the main obligations and exclude the main rights of the other party are invalid. In this case, the platform unilaterally exempted it from the real responsibility of guaranteeing the mileage of vehicles in the transaction, and did not provide evidence to prove that it had fulfilled its obligation of reminding or explaining, so the format clause was invalid.

  Civil fraud refers to the act of deliberately telling the other party false information or deliberately concealing the true information in the process of establishing, changing and terminating civil rights and obligations, and inducing the other party to make a wrong representation. In this case, the second-hand car platform, as a brokerage company specializing in used motor vehicles, has the professional knowledge and detection ability related to vehicles, should know the important information of the vehicles sold by its company, and has the obligation to inform consumers of the real situation of the vehicles, but it fails to accurately inform consumers, which is a deliberate concealment of the real situation, deceiving and misleading consumers to buy the vehicles involved, which constitutes fraud. According to the provisions of China’s Consumer Protection Law, if a business operator commits fraud in providing goods or services, it shall increase the compensation for the losses it has suffered according to the requirements of consumers, and the amount of compensation shall be three times the price of the goods purchased by consumers or the cost of receiving services.

  Buying a car has been delayed.

  You have to pay for your actions

  ■ Case replay

  The plaintiff Ding received a phone call from a used car salesman, saying that someone wanted to buy a Buick Excelle that he hung on the Internet. After many discussions, the final transaction price is 17,000 yuan, provided that the buyer Liu bears the violation of the vehicle. Subsequently, Ding should drive the car to a store. After checking the car, Liu decided to buy it. During the transfer procedures between the two parties, Liu drove the car away privately. Ding appealed to the court and asked Liu to assist in the transfer procedures. The used car trading platform and Liu compensated for the loss of 4,500 yuan. After trial, the court ruled that Liu assisted Ding in handling the vehicle transfer procedures and compensated the other party for a loss of 1,500 yuan.

  ■ Judge’s statement

  In this case, both parties have clearly agreed that both parties shall go through the transfer formalities within 3 working days after the signing of the contract and the full payment of the transaction vehicle price. It is the obligation of both parties to handle the transfer of vehicles, and since the vehicles involved and related procedures have been delivered to Liu, Liu, as the buyer, should assist Ding to handle the transfer procedures. Because the vehicles involved in the case were not handled in violation of regulations, Ding was at fault in causing the dispute in this case. He said that there was no evidence to support the violation at that time, so the court decided on the proportion of its loss. The second-hand car trading platform only acted as an intermediary to facilitate Liu and Ding to reach a sales contract relationship, and had fulfilled their due contractual obligations. Ding asked him to bear the liability for breach of contract, which was unfounded in the law and the court did not support it.

  What the judge needs to remind here is that both buyers and sellers of used cars and platforms should strictly abide by the contract, otherwise they will have to pay for their actions. In this case, the two parties have not gone through the transfer formalities, and Ding will hand over all the formalities of the vehicle and the car keys to the other party. He also bears certain responsibilities for the occurrence of the dispute and should bear the corresponding legal consequences.

  (Author: Haidian District People’s Court, Beijing)

Cross-border innovation of time-honored brands: how to "pair" moon cakes and coke?

  Xinmin Evening News (Reporter Zhang Yuyun) The cross-border innovation of Shencheng time-honored brand has made new moves. This afternoon, two century-old brands, Xinghualou and Coca-Cola, released a co-branded mooncake gift box, which made mooncake, a traditional food in China, an "international norm", and Coca-Cola also added oriental elements.

  In 1851, Xinghualou was born, and Coca-Cola Company was founded in 1886. Two time-honored brands over 300 years old cooperated for the first time across the border, so that moon cakes and Coke formed CP. What kind of sparks would it collide?

  Three joint gift boxes

  The reporter saw at the press conference that Xinghualou and Coca-Cola brought three joint gift boxes. Xinghualou fiber moon cake and Coca-Cola fiber+soda are the protagonists, and both take dietary fiber as a common health selling point. Among them, fiber+soda has 5 grams of dietary fiber per can, which can meet 30% of the fiber demand of human body every day; The fiber moon cake developed by Xinghualou was jointly developed by the team led by the fifth generation moon cake inheritor of Xinghualou. The dietary fiber content was as high as 6%, and its filling ratio was adjusted countless times.

  There are three joint gift boxes, and the collector’s edition gift box draws old Shanghai figures on the outer box, with a limited sale of 5000 boxes. On the high-end version of the gift box, Chang ‘e comes leisurely in Xiangyun, while the selling version of the gift box is painted with elegant peony flowers, all of which are classic patterns of Xinghualou moon cakes, but its background color is bold to choose crystal white to interpret the moonlight color.

  Online celebrity live broadcast "with goods"

  Chen Zhe, general manager of Xinghualou Group, said that before the Mid-Autumn Festival last year, 500 boxes of mooncakes in Xinghualou were airlifted to the American market and won the favor of local overseas Chinese. This year, Xinghualou will continue to expand the Mid-Autumn Festival market in the United States. This time, we jointly launched a joint gift box with Coca-Cola, which kicked off the cross-border cooperation between Xinghualou and famous brands — — In the future, Xinghualou may cooperate with automobile brands and cultural brands, and expand overseas markets to Australia and other places. In the peak season of moon cake sales, that is, in late August, Xinghualou also plans to cooperate with online celebrities to broadcast "bringing goods" live.

  While the white rabbit and Meijiajing launched butterscotch lipstick, they sold the white rabbit milk tea with Happy Lemon. Want Want and Nature Hall cooperated on the mask; LU ZHOU LAO JIAO CO.,LTD and Smell Library launched perfume; Liushen produced a cocktail … … Cross-border innovation of time-honored brands has become a trend, and it is also an "incubator" for online celebrity products and hot topics. Behind it is the efforts of the old brands to compete for strength and develop in the direction of youthfulness and fashion.

About COVID-19 and other respiratory infectious diseases! Shenyang CDC released the latest reminder!

In February, although it is already in beginning of spring, the cold air is still active frequently, and it is chilly in spring, cold at first, and the temperature difference between day and night is large, so it is necessary to continue to pay attention to cold protection and warmth. At the same time, during the Spring Festival holiday, activities such as visiting relatives and friends, going out for a trip, gathering for dinner and other people’s mobility increased significantly, which led to an increase in the risk of disease transmission.

Shenyang CDC reminds residents to focus on the prevention and control of respiratory infectious diseases such as COVID-19, influenza, avian influenza, chickenpox and scarlet fever, viral diarrhea caused by norovirus and rotavirus, zoonotic infectious diseases caused by brucellosis in contact with infected cattle and sheep, and pay attention to the rational use of braziers, coal stoves and gas water heaters to guard against carbon monoxide poisoning.

Covid-19 infection

Shenyang still maintains a low epidemic level.

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The reported cases of Covid-19 infection in Shenyang increased compared with last month, but it remained at a low epidemic level. Among the local cases, the JN.1 mutant strain from Covid-19 has become the dominant epidemic strain, which is affected by factors such as cross-regional mobility and increased crowd aggregation around the Spring Festival. February coincides with the Spring Festival, and the mobility and clustering of people have increased. It is expected that the epidemic situation in COVID-19 will gradually increase, and it is necessary to prevent the outbreak from rebounding and clustering.

Health tips

(1) Strengthen personal health management. Pay close attention to your family and your own health every day. When you have symptoms such as fever, dry cough, fatigue, sore throat, decreased sense of smell, diarrhea, etc., avoid going to school or work with illness, and go to a fever clinic in a nearby hospital as appropriate. Wear a mask all the way to the hospital and try to avoid taking public transport.

(2) It is suggested that the elderly aged 60 and above or those aged 18-59 with serious basic patients, people with low immune function and people with high risk of infection should be given priority to Covid-19 vaccine containing XBB mutant antigen. People who have completed the basic immunization of COVID-19 vaccine (2 doses or more) or who have been infected with Covid-19 and meet the vaccination conditions can be vaccinated.

(3) Wear masks scientifically according to the Guidelines for the Prevention of Respiratory Infectious Diseases (2023 Edition). Other countermeasures can refer to the flu.

flu

A variety of respiratory diseases alternate or co-epidemic.

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The epidemic period of influenza began in October, and in the future, influenza virus will remain the most important pathogen of respiratory diseases. In February, the city will continue to present a trend of alternating or common epidemics of various respiratory diseases. Due to the continuous low temperature and large population movement during the Spring Festival, the data of influenza-like cases will continue to maintain a high level.

Health tips

(1) Encourage the elderly aged 65 and above, patients with basic diseases, children aged 6 months to 5 years, pregnant women, medical staff and other key groups to be vaccinated with influenza vaccine. Do a good job of personal protection and try to go to crowded places as little as possible.

(2) All kinds of crowded institutions and units should do a good job in the prevention and control of influenza, such as ventilation and disinfection, especially in places where air conditioners are turned on for a long time, windows are closed, and regional ventilation is poor.

(3) Open the window regularly for ventilation several times every day to keep the indoor air fresh. During the peak epidemic period, people should avoid going to crowded places. If there are related symptoms, they should seek medical advice in time, stay at home as much as possible, and go to work without illness to reduce the spread of the disease.

highly pathogenic avian influenza (HPAI)

Zhejiang reported H10N5 human avian influenza epidemic.

three

At present, it is the high incidence season of bird-to-bird epidemic during the migration of wild birds, and some areas in the south have closed the live poultry market. The H10N5 human avian influenza epidemic reported in Zhejiang has sounded the alarm. Experts believe that the whole gene analysis of the virus shows that H10N5 virus is avian in origin and does not have the ability to infect people effectively. This epidemic is an sporadic case of cross-species transmission from bird to human, and the risk of human infection is low, and no human-to-human transmission has occurred.

Health tips

(1) The public should avoid contact with sick and dead birds in daily life and try to avoid direct contact with live birds.

(2) Pay attention to food hygiene, improve self-protection awareness, wear a mask and seek medical attention as soon as possible if you have fever and respiratory symptoms.

(3) In the process of fever treatment, it is necessary to explain to the doctor the contact history of the patient’s wild animals and poultry, and never ignore the risk of human infection with avian influenza.

Infectious diarrhea

Risk increases, pay attention to personal protection

four

During the Spring Festival, people have more dinners and gatherings, frequent contacts, increased chances of contact with intestinal pathogens, and increased risk of viral diarrhea. Therefore, we should do a good job in protection and pay attention to personal hygiene and food hygiene and safety.

Health tips

(1) Pay attention to the safety of drinking water: Do not drink raw water, well water or non-standard sterilized water, but drink boiled water or bottled water.

(2) Pay attention to food safety: keep the environment, hands and food clean when preparing food; Separate raw and cooked foods to avoid cross-contamination; Raw fruits and vegetables should be washed; Food is cooked thoroughly to kill microorganisms; Both hot and cold food should be kept at a safe temperature. Choose a restaurant or restaurant with regular and good sanitary conditions to eat, and do not eat spoiled and stale food; Take-away food should be washed or cooked in advance on vehicles and during travel, and kept raw and cooked separately, and should not be stored for too long.

(3) Maintain hand hygiene: Regular hand washing is the most important and effective preventive measure to avoid enterovirus infection. Wash your hands carefully with soap and water for at least 20 seconds.

(4) Regular disinfection: infant bottles, toys, classroom floors, door handles, desks and chairs, teaching AIDS, school buses and other standardized disinfection.

(5) Protection: Wear gloves when cleaning vomit, feces and diapers, and then wash your hands thoroughly.

(6) Seek medical attention early: If symptoms such as nausea, vomiting and diarrhea appear, seek medical attention at the first time, and do not go to work or go to school with illness.

Original title: "About COVID-19 and other respiratory infectious diseases! Shenyang CDC released the latest reminder! 》

Read the original text

852,800 imported interior luxury.

Chinese has a soft spot for big cars. A car with large volume and space can not only bring a strong atmosphere, but also bring a comfortable ride environment to consumers. There are many choices of cars now, as we said today. Now let’s follow Xiaobian to see what it has done.

Let’s take a look at the appearance of the Audi RS 5 first. The front of the Audi RS 5 is relatively handsome, and the grille uses a three-piece shape, which looks simple and generous. Headlights are very delicate and pretty, but the shape is quite young and fashionable. The car is equipped with LED daytime running lights, automatic opening and closing, adaptive far and near light, automatic steering, delayed closing, rain and fog mode and so on. Come to the side of the car, the car body size is 4717MM*1866MM*1371MM, the car uses sharp lines, the car side looks very soft, with large-sized thick-walled tires, the overall visual effect is very solid. In the rear design, the Audi RS 5 rear line is individual, the taillights look very hard-core, and with the unique exhaust pipe, it is still relatively avant-garde in general.

Sitting in the car, the interior style is very simple, and the overall design of the gas field is still in place. The car looks very good outside the steering wheel. It is made of genuine leather and has an atmospheric shape. Take a look at the central control. The car is equipped with a touch-sensitive LCD central control screen, which makes the interior design quite layered and meets the aesthetic standards of most consumers. Let Xiaobian introduce the dashboard and seats. The car is equipped with a clean and refreshing dashboard, which is very eye-catching. The car uses leather seats, equipped with functions such as electric adjustment of auxiliary seat, electric adjustment of seat with memory, and seat proportion tilting, which has good support and comfort.

Audi RS 5 is matched with an automatic manual transmission (AT) gearbox, with an acceleration time of 3.9s seconds per 100 kilometers. The power performance is good and it is completely OK for daily use.

Audi RS 5 space performs well, and the leg head space is quite comfortable, bringing a better ride experience. In addition, the car is equipped with fatigue warning, anti-lock braking (ABS), LED daytime running lights, brake assist (EBA/BAS, etc.), brake force distribution (EBD) main driver airbag, co-pilot airbag, side airbag curtain, front side airbag and other safety configurations.

After reading this car, I believe you have a general understanding. Such a car with the right price can meet the daily practical needs, and it doesn’t take much thought to maintain it at ordinary times, and the price is good.

The Biography of Naruto Bo Ren: A New Endurance Attack: A Review of the Flashy Endurance Stewing.

  Biography of Naruto: New Endurance Attack is a brand-new attempt of Naruto IP, which is different from the extreme storm series that is good at telling stories and performing effects. Naruto: New Endurance Attack focuses on online PVP. In this game, online battle of 4V4 is the main gameplay. Players compete with other players in different modes by teaming up, thus improving their level and dominating Endurance League. The biggest selling point of this game is the powerful customization system. Players will no longer play the role in the original, but create a unique "ninja" by customizing ninja, equipment and image. This also allows it to distinguish itself from the extreme storm series.

  However, this insurmountable "mountain" is undoubtedly a difficult challenge for "Huo Ying: New Endurance Attack". From the previous preview, the first impression of the game is very profound, and the customized system with strong plasticity in 4V4 online battle has successfully attracted the attention of the original fans. Then, can "Huo Ying: New Endurance Attack" carry forward this IP on the road of the game like the extreme storm series?

Wandering stars
The scene between Naruto and Sasuke is as bad as the scene where Batman’s parents died.

  The story of "Huo Ying: New Endurance Attack" happened after the comic book Endurance World War, when Naruto had become Huo Ying. In order to better prevent future wars, Konoha organized a Endurance World League with other villages. The player is a contestant and comes to Muye Village to participate in the competition. Different from playing the original role in other Huoying games, in Huoying: New Endurance Attack, with the powerful custom system of the game, players can pinch out unique roles. The advantage of not controlling the original role is that players can participate in the battle in their own capacity, giving players the greatest sense of participation.

  If you read the original, you will find that although there are many options for each part, most of them actually split the characters’ faces and costumes in the comics for players to choose from. If you don’t like the original role, you can make an identical one according to the role you like.

Wandering stars
From head to toe, clothes to accessories can be customized, and you will often see all kinds of strange and fancy players in the hall.

  The custom system of the game is not limited to the shape of the character, but can be reflected in the "avatar system" of the game. You can understand this system as a profession. Players decide their own role attack methods according to four basic types. Of course, you can switch at any time in the subsequent battles.

  Avatars are mainly divided into attack, defense, shooting and healing. In fact, you can put them in the right place with other basic occupations that are common in online games. Attack is good at melee output, shooting is good at remote output, and most skills of defense are defensive. The more you play an auxiliary role in the team, the more you are a wet nurse, which can support your teammates. Each battle consists of a team of four players. Although theoretically speaking, it is reasonable to output one T and one wet nurse according to the matching of occupations, in fact, in this game, attack and shooting have a great advantage in the battle, and teams like 4 attacks, 2 attacks and 2 shots often appear, while Shouheyue rarely sees them play because of their low attack power.

Wandering stars
The skills of the characters are all familiar moves in the original, and they can be combined at will according to different occupations.

  Each class has two main skills and an arcane meaning, and the weapons it can carry are also different according to different classes. It should be noted that the professional customization system is very powerful. As long as the players upgrade their level, the obtained ninja skills can be matched at will. You can either let the characters open eight armor-dodgers and put spiral pills, or you can use them together with Deidara’s explosives.

Wandering stars
Players can worship the characters in comics as masters and learn their unique skills by upgrading their level.

  Of course, the system also provides players with a number of characters in comics. If you are tired of using custom characters, it is also a pleasure to use a set character.

Wandering stars
As a random game, there are only 20 characters in comics available to players at present.

  It should be noted that playing needs to be connected to the internet all the time. It is not easy to play smoothly. Besides having a good network environment, the server is often disconnected and stuck, which has become a "threshold" that hinders players’ smooth experience. At the same time, each battle needs to be matched on the basis of a player’s network. If the owner’s network is not good, the other seven people in the room will be stuck and affect the battle, or they will be kicked out of the room to match again. This situation of being kicked out without rhyme or reason appears very often in the game.

Wandering stars
This is probably the most common interface you see when you experience the game.

For more information, please pay attention to:

Ten Questions about Pfizer COVID-19 Vaccine

This article comes from WeChat WeChat official account:CC weekly (id: cancer-weekly), Author: Zhang Yujiao (tenured professor of The University of Texas MD Anderson Cancer Center), original title: "Exclusive | These five groups of people cannot be vaccinated! Chinese scholars analyze the top ten problems of Pfizer vaccine, with the title from vision china.

Core summary

1. On the 10th local time, the US Food and Drug Administration(FDA)With 17 votes in favor, 4 votes against and 1 abstention, COVID-19 Vaccine Group decided thatThe benefits of using Pfizer /BioNTech COVID-19 vaccine in adults aged 16 and over outweigh the known risks, and the COVID-19 Vaccine Team of FDA recommended that Pfizer’s COVID-19 vaccine be approved.This means that the last obstacle has been cleared before the COVID-19 vaccine goes on the market in the United States.

2. The vaccination effect of tumor patients receiving chemotherapy and radiotherapy and patients undergoing bone marrow and organ transplantation needs to be studied. People who have been infected should also be vaccinated, but it is not recommended for pregnant women to be vaccinated. Patients with a history of severe allergies should also be carefully vaccinated.

3. At present, it can only be concluded that COVID-19 vaccine is valid for more than half a year.As for how long, we have to wait for the data to speak. According to the current state(Including the titer and maintenance of antibodies in early studies)It may be a year or so, I hope it will be longer.

4. The extent to which COVID-19 vaccine can reduce the chance of spreading virus after vaccination needs further study. Therefore,After vaccination, you need to wash your hands, wear a mask and be socially isolated.

On December 8th, the world’s first Pfizer COVID-19 mRNA vaccine was inoculated in the UK after the third phase clinical study confirmed its effectiveness. The 90-year-old lady told the media at the vaccination site with a strong British accent: "This is the best thing that has happened to me, both effective and free!" . The second vaccinator is an 80-year-old man. His name is William Shakespeare, and he has the same name as the great British writer.

On the same day, after three weeks of investigation, FDA issued a review statement: Pfizer vaccine has no safety concerns, and the effective rate can reach 52% after the first vaccination, and the effective rate will rise to 95% after the second vaccination, and the vaccine can significantly reduce the number of critically ill patients. FDA(US Food and Drug Administration)Decided to submit it to the expert Committee on vaccine efficiency and safety outside the FDA for public hearing, and the whole hearing will be broadcast live on national television.

By 30 FDA independent committees on vaccine efficiency and safety(composed of vaccine experts, doctors and representatives of the public)The hearing will be held from 9: 00 am to 5: 45 pm on December 10, US Eastern Time and December 11, Beijing Time.(Tubing, live broadcast by Twitter). Members of the Committee reviewed tens of thousands of pages of information in advance. After a heated debate, 17 votes in favor and 4 votes against the emergency use of Pfizer mRNA COVID-19 vaccine for adults over 16 years old.

At the hearing, Pfizer released detailed data for the first time. People over 16 years old, including those over 55 years old, have chronic diseases.(including heart and lung disease, cancer history)Those who have a history of HIV, HBV infection but have been controlled are all enrolled in the third phase of the study.

About side effectsMild to moderate discomfort at the inoculation site is very common. Moderate systemic reaction is about 18%, and serious side effects are less than 5%. The research is still going on, and the FDA requires Pfizer to submit updated information to the FDA in January until two years later.

About efficiency95% of the total protection efficiency occurred 7 days after the second inoculation. The protection efficiency of people of all ages and races is above 93%. It has a good protective effect on the history of basic diseases, including cancer.

At the hearing, the safety hazards such as patients with obvious immune deficiency, patients with severe allergic reactions, pregnant women and children were discussed. At the same time, the possibility of transforming mRNA into DNA and reducing the possibility of human-to-human transmission are discussed, and suggestions for future research are put forward, including further research on asymptomatic infected people.

The most controversial issue is whether teenagers aged 16 and 17 can be vaccinated, because there are only more than 100 people in this group in the study.. Some members are opposed to vaccinating teenagers aged 16-17, which is the main reason for voting against it. However, the FDA insists that because many 16-and 17-year-old children in the United States have started working in supermarkets, it is more dangerous.

On December 17th, another mRNA vaccine(Moderna Modena)An FDA hearing will also be held and approval is expected.

After nearly a year of long suffering, people finally saw the dawn. The British media said that "we are vaccinated with hope". However, in the face of more than 1.5 million lives lost around the world, we can’t help but sigh "too late". However, it is worrying that more than 37% of the American people are not willing to be vaccinated at present. They questioned"So soon? Is it safe? !”

Take the United States as an example. Up to now, more than 15 million people in the United States have been infected with COVID-19, and nearly 300,000 people have lost their lives. The second wave of epidemic has just broken out in autumn and winter. Recently, there are 200,000 new cases and more than 2,500 deaths in the United States, far exceeding the first wave in July this year! At this exponential growth rate, if there is no vaccine and effective social isolation, the probability of each American being infected in 2021 will exceed 50%! Each of us should ask ourselves, should we be vaccinated, infected naturally, or locked up at home?The answer is obvious, we have no choice!

At present, nearly one million people have been vaccinated with four vaccines in China. However, the side effects of Pfizer vaccine, such as severe allergy, and whether some immunocompromised people, such as children, cancer patients, organ transplants, pregnant women and AIDS, can be vaccinated, and who can be vaccinated, have also become consistent issues and choices faced by China and the United States. However, the problems encountered in the vaccination of Pfizer vaccine and Modana vaccine in the United States and the United Kingdom will also serve as a reference for the China vaccine that will be widely vaccinated in the future.

First, who will be vaccinated first? What is the final goal?

According to the discussion results of CDC on November 30th, the order of COVID-19 vaccination is as follows:

First batch(From 15 December): frontline medical staff(20 million)And the elderly in nursing homes(millions).

So far, Pfizer will provide 40 million doses of vaccine before the end of the year; Moderna will provide 20 million doses before the end of the year.

Second batch(From January next year)Social necessities, including police, postmen, firefighters, dieters, school teachers, cleaners, food processors, etc.(nearly 90 million). Old people over 65 years old(fifty million).

The third batch: ordinary people(From March next year)It is estimated that more than 100 million people.

The fourth batch: young people and children under the age of 16(From May next year): tens of millions.

MD Anderson medical staff were among the first to be vaccinated. The hospital has subdivided the first batch of personnel:

At present, the Texas government has announced the distribution number of the first batch of Pfizer vaccines in major hospitals. MD Anderson Hospital will receive nearly 5,000 doses of COVID-19 vaccine on the 14th.(two doses for one person), should be able to supply all the clinical medical staff of 1a with vaccination.(The hospital has nearly 1,000 full-time doctors, more than 20,000 full-time employees, and nearly 30,000 people for further study.).

Goal:Strive to reach 70% vaccination rate after June next year, and promote group immunization.(95% effective rate x70% vaccination rate =66.5% immunization rate). In other words, we should stick to wearing masks and social isolation until the end of June next year.(Biden asked people to hold on at least until the end of April). Clear goals, but a long way to go! What should developing countries do if developed countries plan like this?

Figure/COVID-19 vaccine samples developed by Pfizer and BioNTech.

Second, should cancer and other patients with immunodeficiency, or people with severe allergies be vaccinated?

Should cancer and other patients with immunodeficiency, or people with severe allergies be vaccinated? At present, in the third phase of clinical research, tumor patients receiving chemotherapy and radiotherapy, or patients with bone marrow and organ transplantation, HIV, etc., are not allowed to participate in the study because of potential immunosuppression. Therefore, the effect of these patients after vaccination is still a research problem. Related research is being prepared.Generally speaking, if radiotherapy and chemotherapy have stopped for more than one year, cancer patients can consider vaccination.

In addition, two cases of obvious allergic reactions occurred in the population vaccinated in the first week in Britain. Therefore,Experts warn patients with a history of severe allergies to be carefully vaccinated.

3. Should children and pregnant women be vaccinated?

In the current clinical study, neither pregnant women nor children under 12 years old were enrolled. Therefore,Vaccination for pregnant women is not recommended at present. As for teenagers and children(under 16 years old)No further data on safety and effectiveness will be available until May next year.

Fourth, should people who have been infected with COVID-19 be vaccinated?

For people who have been infected,Because the recently reported cases of secondary infection and natural immunity may only last for 3 to 6 months, and the immunity produced by natural infection is weak, they should be vaccinated.

5. How long can immunity last after vaccination?

Since most of the third phase of vaccine research began in July this year, the longest observation time is less than half a year. Therefore, we can only conclude that the validity period is more than half a year at present. As for how long, we have to wait for the data to speak. According to the current state(Including the titer and maintenance of antibodies in early studies)It may be a year or so, I hope it will be longer.

6. After vaccination, will it spread the virus to others? Do you still need to wash your hands, wear a mask and be socially isolated?

At present, the effective rate of mRNA vaccine is 95%, which means that the difference between the number of patients with symptoms accounts for the percentage of the number of patients with symptoms in the control group compared with the random control group that did not receive the vaccine. This is a standard algorithm widely accepted by epidemiology, and it is also a standard index of vaccine listing in the international community, not an invention of a manufacturer. Both Pfizer and Mardner’s vaccine trials rely on patients’ self-reports, and subsequent confirmation tests will only be conducted if there are related symptoms. Therefore, this calculation does not include asymptomatic patients; Secondly, the difference between the two groups in transmission to others has not been detected yet.

Can the vaccine reduce the chance of transmission to others? Scientifically, it should be, but the degree needs further study. Therefore,After the vaccination, it is not necessary to wash your hands, wear masks and be socially isolated. Let’s stick to it for a while and wait for further data.Moreover, the vaccine is not 100% effective, in case you belong to the 5% ineffective population!

Figure/Relevant data of Pfizer vaccine

7. How many times should I be vaccinated? What are the side effects?

Current vaccines all requireInoculate twice. If you only plant it once, the effect will be greatly reduced. Moreover, there must be an interval of three weeks between two times.(Pfizer)Or around.(Mardner). At the same time, the vaccine from the same manufacturer must be vaccinated, even though they are all mRNA vaccines.

As for the side effects, it is a three-point poison. It is an ideal to cure all diseases without side effects; More accurately, it is a fantasy; Be strict, it’s nonsense!

This year, according to the recommendation of CDC in the United States, I have been vaccinated against influenza.(once a year, inactivated vaccine)And herpes zoster vaccine.(Protein vaccine, over 50 years old, administered twice). COVID-19 vaccine is expected to be vaccinated in late December. I don’t have much discomfort after getting the flu vaccine. However, every time I have been vaccinated with herpes zoster vaccine, I have intermittent fever for more than 24 hours, and sometimes fever also causes my whole body to tremble, and my arm is red, swollen and painful for nearly a week. However, I know that these are normal phenomena and belong to mild and moderate side effects.

Based on the available data, most of the side effects of COVID-19 vaccine last for 1-2 days. Common injection site pain, erythema/redness, or fatigue.(Moderna)9.7%, Pfizer(Pfizer)3.8%, fever, chills, muscle aches( Moderna)8.9%, joint pain(Moderna) 5.2%, headache (Moderna)4.5%, Pfizer(Pfizer) 2%。

Long-term side effects need to be followed up in the fourth phase after marketing.

Judging from the information released,MRNA vaccine appears severe(three degrees)The side effect was severe fatigue, accounting for 3.7%. Overall, it is very safe.Mild and moderate discomfort similar to a cold is very common and normal. Please be patient!

Figure/After the first vaccination, patients will get a card to remind them to get the second vaccination on time.

8. Will the new virus mutation affect the effectiveness of the vaccine?

The answer is possible. For example, the mutation rate of influenza virus gene is high, so a new vaccine against influenza in that year should be vaccinated every year. And AIDS has always been because the virus mutates too fast, so far there is no vaccine.

Fortunately, according to the current epidemiological survey, Nature Communications magazine published an article in November this year to study 46,000 cases of COVID-19 virus from different periods around the world, and found that the probability of COVID-19 mutation is relatively low because of its unique proofread inspection mechanism, which is undoubtedly the gospel of the vaccine. At the same time, the mRNA vaccine can be modified according to mutation and then reproduced, which is much easier to operate than the terminal protein vaccine. For example, the gun has been built, just need to modify the structure of the warhead.

9. Why should vaccine storage be at MINUS 70 degrees?

Pfizer vaccine needs to be stored in a freezer at MINUS 70 degrees Celsius for a long time, and it can only be stored in a refrigerator at 2 ~ 7 degrees Celsius for 5 days. Moderna vaccine can be stored for a long time in the freezer at MINUS 20 degrees, and can be stored in the refrigerator at 2 ~ 7 degrees for one month. The reason why RNA is sensitive to temperature is that it is easy to degrade with the increase of temperature. Moderna vaccine is relatively thermotolerant, which may be related to the composition and structure of its lipid carrier. This partly explains that the side effects of Moderna vaccine seem to be a little high.

AstraZeneca’s vaccine is an adenovirus strain, which requires lower temperature and can be stored for half a year at 2 ~ 7 degrees. And is suitable for developing countries.(Note: Freund’s temperature F is used in American charts). However, the comprehensive effective rate of AZ vaccine is about 70%. Subgroup analysis showed that the effective rate of the first low dose group was 90%. However, because this group of people is young.(under 50 years old)And it is not designed in advance. Therefore, it is recognized by the industry as 70% efficient.

Photo/Pfizer is building a "frozen farm" the size of a football field to store vaccines in Kalamazoo, Michigan. Pfizer’s vaccine must be stored below the ultra-low temperature of 70 degrees.

X. Why do Britain and America prefer mRNA vaccine?

On December 2nd, Britain took the lead in approving Pfizer’s vaccine and started vaccination on the 8th. Today, the vaccine has also been approved in the United States, and it is expected to start nationwide vaccination on the 15th. On the 17th of next week, the FDA of the United States is very likely to approve the mRNA vaccine of Moderna, and it is possible to start vaccination on the 22nd. Apart from the fact that these two viruses first completed the phase III clinical randomized study, what factors made the world look at the mRNA vaccine with new eyes?

Thirty years ago, I transferred from tumor immunology research to a brand-new field of tumor gene therapy. At the MD Anderson Cancer Center in the United States, my colleagues and I spent seven years constructing a retrovirus, adenovirus and nanoliposome-mediated anti-cancer gene transformation mode and animal tumor model, which not only contributed to the first patient’s cancer gene therapy in human history, but also made a Nasdaq-listed company. I have published more than a dozen papers myself, won two patents for gene therapy, and obtained a doctorate in tumor biology within four years. After that, I decided to return to the clinical front line and started five years of standardized training for clinical oncology residents.

Retroviruses have the longest gene transformation rate and maintenance time, but unfortunately they will be integrated into the DNA of human hosts. Some scholars are worried about the possibility of cancer. At present, this gene transformation method has been rarely used in cancer treatment.

Adenovirus will not be integrated into human DNA, but it is toxic to cells and will cause immunity to adenovirus vectors. This may explain the side effects of AstraZeneca COVID-19 adenovirus vector vaccine and the change of the initial dose to the effective rate.The high dose of the first vaccination may stimulate a stronger immune response against adenovirus vector, which may affect the results of the second vaccination. Therefore, it is better to use a low dose for the first time).

However, nanotechnology liposome itself has little influence on the immune system, and the general mRNA will not be reverse transcribed and integrated into human DNA, but it will express the protein to be transmitted in human cells for a short time.(For example, COVID-19 spinous protein activates the immune response and then gradually subsides), the best security. However, I used DNA plasmid at that time; Because DNA is much more stable. At that time, everyone knew that RNA extraction and preservation were very difficult, and there was no precedent for successful transformation of mRNA gene.

Gene transfer with COVID-19 spinous protein mRNA as the main body mediated by lipid carrier can avoid errors and potential side effects in the process of DNA transcription, so that spinous protein can be efficiently expressed in human cells in a short time, and the immune response of the body can be activated, which can produce specific antiviral antibodies and immune killer cells more effectively than natural infection. Although the gene expression is short-lived, activated B cells and T cells have their own memories, which can destroy or inhibit the virus for a long time. At the same time, this mRNA will not reverse transcribe into DNA, and will not be integrated into the host DNA, which is safe and reliable.

For decades, the method of mRNA gene transfer has been a dream of scientists. Katalin Kariko, the founding partner of Moderna, the inventor of mRNA technology and a Hungarian-born American scientist, has been on the bench for 40 years, and was originally prepared to set up Moderna to engage in mRNA cancer vaccine. As a result, a Cheng Yaojin COVID-19 was killed halfway.

When scientists in China announced the gene sequence of COVID-19 on January 10th this year.(including spinous process protein)Later, the researchers in the United States and Germany changed hands, but they were unwilling to plant flowers and flowers. Fortunately, this spinous protein was finally proved to be a good immunogen of COVID-19, and COVID-19 mRNA vaccine appeared on the scene. This is an important breakthrough in human science and technology, and it is also the result of the joint efforts of scientists from all over the world.

In contrast, inactivating virus vaccine is a mature method, and this traditional method is adopted in the annual influenza vaccine. Its research and development success rate is high, so it is widely used. However, it is difficult to control the temperature during inactivation, which brings some difficulties to quality control. Therefore, the production capacity is limited. At the same time, the added chemicals will also bring some side effects.

Generally, the effective rate of inactivated influenza vaccine is between 50% and 70%. At present, the early toxicity and antibody positive rate of domestic COVID-19 vaccine with inactivated vaccine as the main body and adenovirus vector have been reported. Volunteers can tolerate mild and moderate side effects, and the antibodies are positive after injection. However, positive antibody does not guarantee that it has sufficient protection. The effective rate must be obtained in the three-phase randomized study with control group. Because the epidemic situation in China is well controlled, the corresponding research must be carried out in other countries with high incidence.

Up to now, the epidemiological efficiency of the strict phase III clinical randomized study of vaccines in China has not been reported, and the world is eagerly awaiting it. I believe the final conclusion will be heard in the near future.The advantages of inactivated vaccine and adenovirus vector vaccine are that they are less affected by temperature, easy to store and transport, and more suitable for developing countries.

Due to the potential advantages of technological innovation and high antigen purification and expression, such as improving vaccine efficiency and productivity and reducing side effects, when the effective rate of mRNA COVID-19 vaccine reached 95%, the industry unanimously hailed this major breakthrough. More importantly, there are almost no seriously ill patients among the vaccinators.

Many people think that this is the arrival of God’s grace! Developed countries such as the United States and Britain have booked the products of these two companies in advance. China’s Fosun Company also signed a cooperation agreement with Pfizer and has completed the first phase of clinical trials. It is expected that the related Phase 2 will be launched in China soon.(Non-random)Clinical research to obtain the approval of China FDA.

Figure/A nurse and patient in California. In many parts of the United States, the pressure on the health system has been overwhelmed and is on the verge of collapse at any time.

Although American health insurance and the government will pay the cost of vaccination, another difficulty is that more than 37% people in the United States are not at ease with the vaccine and are not prepared to vaccinate immediately. In this regard, three former presidents of the United States, Bush, Clinton and Obama, said that they would vaccinate under the observation of the media at the first time as a platform for vaccine safety.

Because the vaccine is for normal people, it is not a "medicine", not to treat patients, but to prevent diseases. Meanwhile, for COVID-19 vaccine, the population to be vaccinated is billions of healthy people, including children.Therefore, its safety must be much stricter than that of "medicine".Therefore, if time is not pressing, all new vaccines should wait for a long time.(more than 2 years)The data will be finally approved. But in the face of a serious epidemic, this is irrational. The regulations that allow emergency use are designed for this situation.

At present, FDA requires that the last patient should be observed for at least 2 months after entering the Phase III clinical study to ensure that there are no serious acute side effects. Moreover, regulators must strictly control the use of these new vaccines from the beginning. The initial use of these vaccines is limited to those who need them most-doctors, nurses, other health care workers, and the elderly in nursing homes. Regulators also need to continue to closely monitor the side effects of vaccines already on the market.(so-called Phase IV Clinical Study). With the accumulation of data in the first two months of next year, the range of vaccinators will be further expanded.

The development of human society always strives for survival first, and then for improvement and perfection.

When the hopes of the whole world are pinned on the COVID-19 vaccine, the hardest work has just begun. We know that the best antiviral function of the vaccine will not be realized until two weeks after the second vaccination.In other words, for most people, December this year, January and February next year will be the darkest moments in the medical history of the United States since the Spanish influenza pandemic in World War I.

According to Dr. Fauci, director of the Institute of Infectious Diseases of the National Institutes of Health, it is estimated that by March next year, about 500,000 people in the United States will die in COVID-19, surpassing the number of deaths in World War II in the United States.(about 400,000). Regrettably, some people in the United States still refuse to wear masks and social isolation. Up to now, 37% people are skeptical about vaccines, and the epidemic prevention work has a long way to go!

Controversy over vaccines(Inoculation or non-inoculation, domestic or imported)The reason and background are very complicated, and it will not stop for a while. As a scientist and a doctor, I care most about yourself! Vaccinate, not only for others, but also for yourself!


This article comes from WeChat WeChat official account:CC weekly (id: cancer-weekly), Author: Zhang Yujiao (tenured professor of The University of Texas MD Anderson Cancer Center)

Stephy revealed that he had bought fake brand-name bags and cut his double eyelids when he was a sophomore in micro-plastic surgery.

1905 movie network news Recently, Stephy, who plays Chen Ke in the play, has also been hotly discussed by netizens because of its popularity. In an interview recently, she also recalled all the things that she worked hard alone in Beijing. However, she did not use the word "drifting north", but chose the more kinetic "running north".


Stephy revealed that he had nosebleeds every day when he first came to Beijing, and once suspected that he had leukemia. It was also revealed that it was particularly like having a brand-name bag, but because it was not enough, I could only buy a fake bag. But in the end, through hard work, I bought the same real bag.


In response to the heated discussion about double eyelids, a response from Stephy of honest and frank was cut in Weibo before. She also admitted: "Double eyelids were cut when I was a freshman or a sophomore, that is, the technology was not as natural as it is now." Regarding the netizen’s suggestion to consider the adjustment of double eyelids, Stephy said: "If the makeup painting is good, it doesn’t need plastic surgery to assist, and makeup is particularly powerful. I just want to share my beauty products with you sometime. "